octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thomson AB | The level of dietary protein and carbohydrate has a different effect on intestinal uptake of hexoses and lipids in rabbits with an ileal resection than in those with an intact intestinal tract. | 1987 | Can. J. Physiol. Pharmacol. | pmid:3567736 |
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Jandacek RJ et al. | The rapid hydrolysis and efficient absorption of triglycerides with octanoic acid in the 1 and 3 positions and long-chain fatty acid in the 2 position. | 1987 | Am. J. Clin. Nutr. | pmid:3578095 |
Cole SG et al. | Cholesteryl octanoate breath test. Preliminary studies on a new noninvasive test of human pancreatic exocrine function. | 1987 | Gastroenterology | pmid:3678753 |
Cistola DP et al. | Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites. | 1987 | J. Biol. Chem. | pmid:3611099 |
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Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
Reik LM et al. | A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymes. | 1987 | J. Immunol. Methods | pmid:3598193 |
Halestrap AP | The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. | 1987 | Biochem. J. | pmid:3663110 |
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Rösen P et al. | Myocardial performance and metabolism in non-ketotic, diabetic rat hearts: myocardial function and metabolism in vivo and in the isolated perfused heart under the influence of insulin and octanoate. | 1986 Nov-Dec | Basic Res. Cardiol. | pmid:3545178 |
Kuhara T et al. | Identification and quantification of octanoyl glucuronide in the urine of children who ingested medium-chain triglycerides. | 1986 | Biomed. Environ. Mass Spectrom. | pmid:2948585 |
Harris RA et al. | Regulation of branched-chain alpha-ketoacid dehydrogenase complex by covalent modification. | 1986 | Adv. Enzyme Regul. | pmid:3028049 |
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Webb T | Identification of interference affecting the gas-liquid chromatography analysis of valproic acid in quality control material. | 1986 | Pathology | pmid:3097616 |
Whyte RK et al. | Excretion of dicarboxylic and omega-1 hydroxy fatty acids by low birth weight infants fed with medium-chain triglycerides. | 1986 | Pediatr. Res. | pmid:3080726 |
Merrill AR et al. | Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. | 1986 | Biochim. Biophys. Acta | pmid:3081028 |
Veerkamp JH et al. | An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. | 1986 | Biochim. Biophys. Acta | pmid:3081042 |
Fatania HR et al. | Modulation of pyruvate dehydrogenase kinase activity in cultured hepatocytes by glucagon and n-octanoate. | 1986 | Biochem. J. | pmid:3707545 |
Letko G and Halangk W | Effect of improved hydrogen supply on energy state, ureogenesis and gluconeogenesis in isolated hepatocytes. | 1986 | Biomed. Biochim. Acta | pmid:3707550 |
Okita M et al. | Plasma level of branched chain alpha-amino acids following its alpha-keto acid administration to rats. | 1986 | J. Nutr. Sci. Vitaminol. | pmid:3712111 |
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Amendt BA and Rhead WJ | The multiple acyl-coenzyme A dehydrogenation disorders, glutaric aciduria type II and ethylmalonic-adipic aciduria. Mitochondrial fatty acid oxidation, acyl-coenzyme A dehydrogenase, and electron transfer flavoprotein activities in fibroblasts. | 1986 | J. Clin. Invest. | pmid:3722376 |
ChacÃn J et al. | Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. | 1986 | Am. J. Physiol. | pmid:3090895 |