octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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GEYER RP et al. | Metabolism of emulsified trilaurin (-C1400-) and octanoic acid (-C1400-) by rat tissue slices. | 1949 | J. Biol. Chem. | pmid:18139198 |
CRANDALL DI et al. | Studies of acetoacetate formation with labeled carbon; the conversion of zeta-(C7)-labeled octanoate to acetoacetate. | 1949 | J. Biol. Chem. | pmid:15393802 |
LORBER V et al. | Conversion of octanoic acid to rat liver glycogen, studied with C14, C13-labeled octanoate. | 1949 | J. Biol. Chem. | pmid:15393766 |
VESTLING CS and WILLIAMS JN | The oxidation of octanoate by liver homogenates from leucemic mice. | 1949 | Cancer Res. | pmid:15392816 |
FIELD J and DRYER RL | Effect of sodium caprylate on the thermal stability of the respiratory system in rat brain. | 1947 | Fed. Proc. | pmid:20342637 |
KIPPLE HM et al. | Cardiovascular effects of sodium caprylate in the cat. | 1947 | J. Pharmacol. Exp. Ther. | pmid:20295511 |
ELLIOTT HW et al. | The effect of sodium caprylate on the cardiac output of the isolated frog heart. | 1947 | J. Pharmacol. Exp. Ther. | pmid:20281335 |
KEENEY EL | Sodium caprylate; a new and effective treatment for moniliasis of the skin and mucous membranes. | 1946 | Bull Johns Hopkins Hosp | pmid:20984783 |
VESTLING CS and KAUFMAN S | The oxidation of octanoate by normal and leucemic mouse liver homogenates. | 1946 | J. Biol. Chem. | pmid:21001223 |
HALL VE and WALDMAN MS | Toxicity of stabilizers for concentrated human albumin solutions; production of cardiac arrhythmias in cats by sodium salts of caprylic and related fatty acids. | 1946 | J. Pharmacol. Exp. Ther. | pmid:20274545 |
KEENEY EL and AJELLO L | Sodium caprylate; a new and effective treatment for dermatomycosis of the feet. | 1945 | Bull Johns Hopkins Hosp | pmid:21011144 |
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Hu Y et al. | Degradation behavior of poly(epsilon-caprolactone)-b-poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles in aqueous solution. | Biomacromolecules | pmid:15360284 | |
Boushaba R et al. | Kinetics of whole serum and prepurified IgG digestion by pepsin for F(ab')2 manufacture. | Biotechnol. Prog. | pmid:12892479 |