| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Librán-Pérez M et al. | Effects of insulin treatment on the response to oleate and octanoate of food intake and fatty acid-sensing systems in rainbow trout. | 2015 | Domest. Anim. Endocrinol. | pmid:26226227 |
| Kajimoto M et al. | Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26232235 |
| pmid:26253695 | ||||
| Kim SA and Rhee MS | Use of caprylic acid to control pathogens (Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium) in apple juice at mild heat temperature. | 2015 | J. Appl. Microbiol. | pmid:26257401 |
| Wang L et al. | Octanoylated ghrelin attenuates angiogenesis induced by oxLDL in human coronary artery endothelial cells via the GHSR1a-mediated NF-κB pathway. | 2015 | Metab. Clin. Exp. | pmid:26277200 |
| pmid:26280674 | ||||
| Fredrickson J et al. | The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model. | 2015 | J. Assist. Reprod. Genet. | pmid:26342329 |
| Parshintsev J et al. | Desorption atmospheric pressure photoionization high-resolution mass spectrometry: a complementary approach for the chemical analysis of atmospheric aerosols. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26395607 |
| Rosiak J and Olejniczak J | [Polymer materials for biomedical use obtained by radiation methods. IV. The therapeutic system for local release of prostaglandins]. | 1989 | Polim Med | pmid:2641404 |
| Oiso S et al. | Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. | 2015 | J Oleo Sci | pmid:26521811 |
| Constantin J et al. | Octanoate transport in the isolated, perfused rat liver. | 1989 | Braz. J. Med. Biol. Res. | pmid:2667669 |
| Fildes FJ and Oliver JE | Interaction of cortisol-21-palmitate with liposomes examined by differential scanning calorimetry. | 1978 | J. Pharm. Pharmacol. | pmid:26761 |
| Diaz De Rienzo MA et al. | Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26825819 |
| Küster J et al. | Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. | 1989 | Biol. Chem. Hoppe-Seyler | pmid:2692615 |
| Voller B et al. | Dose-escalation study of octanoic acid in patients with essential tremor. | 2016 | J. Clin. Invest. | pmid:26927672 |
| Kubota K et al. | The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. | 2016 | Eur J Pharm Sci | pmid:26965004 |
| pmid:26991359 | ||||
| Zhong Z et al. | Effect of fatty acids on formation, distribution, storage, and release of benzo(a)pyrene phenols and glucuronides in the isolated perfused rat liver. | 1989 | Cancer Res. | pmid:2702643 |
| Zieve L and Dozeman R | Effect of hepatic failure toxins on regenerative enzymes in the liver after injury with galactosamine in the rat. | 1989 | J. Lab. Clin. Med. | pmid:2703758 |
| pmid:27055779 | ||||
| Van Hoogdalem EJ et al. | Rate-controlled rectal absorption enhancement of cefoxitin by co-administration of sodium salicylate or sodium octanoate in healthy volunteers. | 1989 | Br J Clin Pharmacol | pmid:2706190 |
| pmid:27098977 | ||||
| González-Manchón C et al. | Control of hepatic gluconeogenesis: role of fatty acid oxidation. | 1989 | Arch. Biochem. Biophys. | pmid:2712567 |
| pmid:27136899 | ||||
| pmid:27161492 | ||||
| Tsaconas C et al. | Gas chromatographic-mass spectrometric assessment of the pharmacokinetics of amineptine and its main metabolite in volunteers with liver impairment. | 1989 | J. Chromatogr. | pmid:2722999 |
| dos Santos MC et al. | Purification of F(ab')2 anti-snake venom by caprylic acid: a fast method for obtaining IgG fragments with high neutralization activity, purity and yield. | 1989 | Toxicon | pmid:2728022 |
| Sawatani Y et al. | Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. | 2016 | Bioorg. Med. Chem. | pmid:27301681 |
| Lemarié F et al. | Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. | 2016 | Biochim. Biophys. Acta | pmid:27317984 |
| Lockman KA et al. | Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. | 2016 | Lipids Health Dis | pmid:27368608 |
| pmid:27418358 | ||||
| Igawa T et al. | Effect of absorption promoters in intranasal administration of human fibroblast interferon as a powder dosage form in rabbits. | 1989 | Chem. Pharm. Bull. | pmid:2743486 |
| Kateja N et al. | Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR). | 2016 | Biotechnol J | pmid:27447837 |
| Hogan S et al. | Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. | 2016 | Antimicrob. Agents Chemother. | pmid:27458213 |
| Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
| Vauhkonen M and Somerharju P | Parinaroyl and pyrenyl phospholipids as probes for the lipid surface layer of human low density lipoproteins. | 1989 | Biochim. Biophys. Acta | pmid:2765542 |
| Yoshida Y et al. | Reye syndrome: rate of oxidation of fatty acids in leukocytes and serum levels of lipid peroxides. | 1989 | J. Exp. Pathol. | pmid:2769452 |
| Kandula M et al. | Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. | 2016 | Int. Immunopharmacol. | pmid:27716592 |
| Lala AK and Koppaka V | Transverse location of new fluorene based depth dependent fluorescent probes in membranes--quenching studies with 9,10-dibromostearic acid. | 1989 | Photochem. Photobiol. | pmid:2772065 |
| pmid:27742199 | ||||
| Dean HG et al. | HPLC analysis of brain and plasma for octanoic and decanoic acids. | 1989 | Clin. Chem. | pmid:2776322 |
| Ashwood-Smith MJ et al. | The use of Albuminar 5 as a medium supplement in clinical IVF. | 1989 | Hum. Reprod. | pmid:2778056 |
| Singh AK et al. | Effect of fatty acids and their derivatives on mitochondrial structures. | 1989 | J. Exp. Pathol. | pmid:2778551 |
| Zhang K et al. | Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. | 2017 | Appl. Biochem. Biotechnol. | pmid:27832512 |
| Temponi M et al. | Purification of murine IgG monoclonal antibodies by precipitation with caprylic acid: comparison with other methods of purification. | 1989 | Hybridoma | pmid:2784406 |
| Clarke D et al. | Surface attachment of active antimicrobial coatings onto conventional plastic-based laminates and performance assessment of these materials on the storage life of vacuum packaged beef sub-primals. | 2017 | Food Microbiol. | pmid:27889148 |
| Vanheel H et al. | Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. | 2017 | Am. J. Gastroenterol. | pmid:27958284 |
| Saito K et al. | An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | 2017 | Toxicol In Vitro | pmid:27965148 |
| Ganz R et al. | Ammonia-induced swelling of rat cerebral cortical slices: implications for the pathogenesis of brain edema in acute hepatic failure. | 1989 | Metab Brain Dis | pmid:2796874 |
| Makhmudov ES and Akhmerov RN | [Characteristics of the oxidation of the intermediates of carbohydrate and fat metabolism in the liver mitochondria of young rabbits during perinatal development]. | 1989 Jul-Aug | Ontogenez | pmid:2797708 |
| Sulkers EJ et al. | Quantitation of oxidation of medium-chain triglycerides in preterm infants. | 1989 | Pediatr. Res. | pmid:2797943 |
| Nakajima K et al. | Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. | 2016 | Biomed. Res. | pmid:28003581 |
| Das K and Ghosh M | Structured DAG oil ameliorates renal injury in streptozotocin-induced diabetic rats through inhibition of NF-κB and activation of Nrf2 pathway. | 2017 | Food Chem. Toxicol. | pmid:28025123 |
| Andrade López JM et al. | Genetic basis of octanoic acid resistance in Drosophila sechellia: functional analysis of a fine-mapped region. | 2017 | Mol. Ecol. | pmid:28035709 |
| Kristev A et al. | The effect of octanoic fatty acid on the cardiovascular system of the guinea pig. | 1989 | Cor Vasa | pmid:2805707 |
| Pégorier JP et al. | Octanoate metabolism in isolated hepatocytes and mitochondria from fetal, newborn and adult rabbit. Evidence for a high capacity for octanoate esterification in term fetal liver. | 1989 | Eur. J. Biochem. | pmid:2806250 |
| Mitkov D et al. | On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome. | 1989 | Res Exp Med (Berl) | pmid:2813970 |
| Fontaine P et al. | Medium chain length polyhydroxyalkanoates biosynthesis in Pseudomonas putida mt-2 is enhanced by co-metabolism of glycerol/octanoate or fatty acids mixtures. | 2017 | Int. J. Biol. Macromol. | pmid:28174083 |
| Lourenço A et al. | Antimicrobial treatments to control Listeria monocytogenes in queso fresco. | 2017 | Food Microbiol. | pmid:28213034 |
| McDonough KH et al. | Effects of oxygen radicals on substrate oxidation by cardiac myocytes. | 1987 | Biochim. Biophys. Acta | pmid:2822138 |
| Widebäck K | Binding of albumin fragments to surface receptor in A, C, and G streptococci. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:2823527 |
| Baraldi M et al. | An increase in cerebral benzodiazepine receptors induced by a subacute administration of ammonia, mercaptans and short-chain fatty acids in rats. | 1987 | Clin. Sci. | pmid:2826071 |
| Besada-Lombana PB et al. | Engineering Saccharomyces cerevisiae fatty acid composition for increased tolerance to octanoic acid. | 2017 | Biotechnol. Bioeng. | pmid:28294288 |
| Barbee RW et al. | T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. | 1988 | Am. J. Physiol. | pmid:2830793 |
| Köllner S et al. | Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin. | 2017 | Eur J Pharm Biopharm | pmid:28323109 |
| Du J et al. | Molecular basis of P450 OleT: an investigation of substrate binding mechanism and major pathways. | 2017 | J. Comput. Aided Mol. Des. | pmid:28342136 |
| Alva-Murillo N et al. | Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization. | 2017 | Front Cell Infect Microbiol | pmid:28361042 |
| Centeno JA et al. | Recovering traditional raw-milk Tetilla cheese flavour and sensory attributes by using Kocuria varians and Yarrowia lipolytica adjunct cultures. | 2017 | Int. J. Food Microbiol. | pmid:28384620 |
| Connolly E and Nedergaard J | Beta-adrenergic modulation of Ca2+ uptake by isolated brown adipocytes. Possible involvement of mitochondria. | 1988 | J. Biol. Chem. | pmid:2839496 |
| Kawai A et al. | Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions. | 2017 | Biochim Biophys Acta Proteins Proteom | pmid:28473296 |
| Ando Y et al. | Synthesis of acylated SOD derivatives which bind to the biomembrane lipid surface and dismutate extracellular superoxide radicals. | 1988 | FEBS Lett. | pmid:2847946 |
| Goussen C et al. | Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. | 2017 | BioDrugs | pmid:28508264 |
| Hsieh CH et al. | The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. | 2017 | Biochemistry | pmid:28603981 |
| Oberhaensli RD et al. | Effect of norepinephrine on ketogenesis, fatty acid oxidation, and esterification in isolated rat hepatocytes. | 1985 | Diabetes | pmid:2862086 |
| Thomas JD et al. | The carboxylic and amino acid chemoreception niche of Bulinus rohlfsi (Clessin), the snail host of Schistosoma haematobium. | 1985 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2865079 |
| Khabbush A et al. | Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet. | 2017 | Epilepsia | pmid:28682459 |
| Peyser RD et al. | Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. | 2017 | Insect Mol. Biol. | pmid:28703934 |
| Caviglia GP et al. | Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by 13C-octanoic Acid Breath Test. | 2017 | Minerva Med. | pmid:28707862 |
| Forest C et al. | A preadipocyte clonal line from mouse brown adipose tissue. Short- and long-term responses to insulin and beta-adrenergics. | 1987 | Exp. Cell Res. | pmid:2877896 |
| Jadhav A et al. | The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting. | 2017 | J Med Food | pmid:28922057 |
| Ishizawa T et al. | Enhancement of jejunal and colonic absorption of fosfomycin by promoters in the rat. | 1987 | J. Pharm. Pharmacol. | pmid:2892912 |
| Moore KH et al. | Hepatic hydrolysis of octanoyl-CoA and valproyl-CoA in control and valproate-fed animals. | 1988 | Int. J. Biochem. | pmid:2895026 |
| Kato A and Iwata S | In vitro study on corneal permeability to bunazosin. | 1988 | J. Pharmacobio-dyn. | pmid:2898016 |
| Reichmann H et al. | Enzymes of fatty acid beta-oxidation in developing brain. | 1988 | J. Neurochem. | pmid:2899130 |
| Kato A and Iwata S | Corneal permeability to bunazosin in rabbits. | 1988 | J. Pharmacobio-dyn. | pmid:2900888 |
| Kato A and Iwata S | Studies on improved corneal permeability to bunazosin. | 1988 | J. Pharmacobio-dyn. | pmid:2902207 |
| Murtuza MI and Isokawa M | Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. | 2018 | J. Neurochem. | pmid:29063591 |
| Van Hoogdalem EJ et al. | The influence of components on the rectal absorption of cefazolin in rats. | 1988 | J. Pharm. Pharmacol. | pmid:2907567 |
| Brass EP and Garrity MJ | Modulation of prostaglandin E2 catabolism and action by fuel substrates in rat hepatocytes. | 1989 | Biochim. Biophys. Acta | pmid:2912505 |
| Augustin K et al. | Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. | 2018 | Lancet Neurol | pmid:29263011 |
| Rybczynska M and Csordas A | Chain length-dependent interaction of free fatty acids with the erythrocyte membrane. | 1989 | Life Sci. | pmid:2927261 |
| Remy-Heintz N and Bali JP | [Demonstration of glycoprotein antigens associated with stomach tumors]. | 1985 | C. R. Seances Soc. Biol. Fil. | pmid:2935234 |
| Kössler F et al. | Depressive effects of free fatty acids on the development of tension in different muscle types. | 1986 | Biomed. Biochim. Acta | pmid:2938577 |
| Vacchina P et al. | Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. | 2018 | Exp. Parasitol. | pmid:29409741 |
| Kuhara T et al. | Identification and quantification of octanoyl glucuronide in the urine of children who ingested medium-chain triglycerides. | 1986 | Biomed. Environ. Mass Spectrom. | pmid:2948585 |
| Polácek H et al. | Study of cough in anaesthetized cats with experimental pulmonary oedema. | 1986 | Physiol Bohemoslov | pmid:2950532 |
| Carr C and Morrison DC | Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes. | 1985 | Infect. Immun. | pmid:2989182 |
| Lohse MJ et al. | Effects of temperature and membrane phase transitions on ligand binding to alpha 2-receptors of human platelets. | 1986 | Mol. Pharmacol. | pmid:3005830 |
| Ayuso MS et al. | Interrelation between gluconeogenesis and hepatic protein synthesis. | 1986 | Biochim. Biophys. Acta | pmid:3015233 |
| Connolly E et al. | Norepinephrine-induced Na+ influx in brown adipocytes is cyclic AMP-mediated. | 1986 | J. Biol. Chem. | pmid:3021738 |