octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

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What functions are associated with octanoic acid?


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What lipids are associated with octanoic acid?

Related references are published most in these journals:

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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Nomura T et al. Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. 1983 Biochim. Biophys. Acta pmid:6317044
Salesse R and Garnier J Adenylate cyclase and membrane fluidity. The repressor hypothesis. 1984 Mol. Cell. Biochem. pmid:6323963
Demol P and Sarles H Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. 1978 J. Physiol. (Lond.) pmid:633115
Zieve L et al. Toxicity of a fatty acid and ammonia: interactions with hypoglycemia and Krebs cycle inhibition. 1983 J. Lab. Clin. Med. pmid:6343534
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
Kochel PJ et al. Effects of noncarbohydrate substrates on protein synthesis in hearts from fed and fasted rats. 1984 J. Mol. Cell. Cardiol. pmid:6374161
Hansford RG Lipid oxidation by heart mitochondria from young adult and senescent rats. 1978 Biochem. J. pmid:637843
Reed WD et al. The effects of insulin and glucagon on ketone-body turnover. 1984 Biochem. J. pmid:6383348
Bijlsma R and Kerver JW The effect of DDT on the polymorphism at the G6pd and Pgd loci in Drosophila melanogaster. 1983 Genetics pmid:6404694
Derr RF and Draves K Methanethiol metabolism in the rat. 1983 Res. Commun. Chem. Pathol. Pharmacol. pmid:6407074
Becker CM and Harris RA Influence of valproic acid on hepatic carbohydrate and lipid metabolism. 1983 Arch. Biochem. Biophys. pmid:6407400
McDonough KH and Spitzer JJ Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. 1983 Proc. Soc. Exp. Biol. Med. pmid:6412237
Nagi MN et al. Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase. 1983 Arch. Biochem. Biophys. pmid:6416174
Hampson RK et al. Regulation of the glycine cleavage system in the isolated perfused rat liver. 1984 J. Biol. Chem. pmid:6420402
Scholz R et al. Influence of fatty acids on energy metabolism. 1. Stimulation of oxygen consumption, ketogenesis and CO2 production following addition of octanoate and oleate in perfused rat liver. 1984 Eur. J. Biochem. pmid:6426957
Meisner H and Neet K Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. 1978 Mol. Pharmacol. pmid:642932
Blumenthal SA Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action. 1984 Biochem. J. pmid:6430273
Duran M et al. The differential diagnosis of dicarboxylic aciduria. 1984 J. Inherit. Metab. Dis. pmid:6434845
Schudt C and Simon A Effects of sodium 2-[5-(4-chlorophenyl)pentyl]-oxirane-2-carboxylate (POCA) on carbohydrate and fatty acid metabolism in liver and muscle. 1984 Biochem. Pharmacol. pmid:6437406
Allen PC Physiological responses of chicken gut tissue to infection with Eimeria acervulina. 1984 Oct-Dec Avian Dis. pmid:6441557
Felix R and Fleisch H Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates. 1981 Biochem. J. pmid:6458286
Buxton DB et al. Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart. 1984 Biochem. J. pmid:6477487
Kim CS et al. L-carnitine: therapeutic strategy for metabolic encephalopathy. 1984 Brain Res. pmid:6478235
Sundqvist KE et al. Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. 1984 Biochim. Biophys. Acta pmid:6487652
Zieve L et al. Brain methanethiol and ammonia concentrations in experimental hepatic coma and coma induced by injections of various combinations of these substances. 1984 J. Lab. Clin. Med. pmid:6491466
Riecken EO [Structural and functional findings in experimental blind loop syndrome]. 1984 Nahrung pmid:6493325
Wagenmakers AJ et al. Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation. 1984 Biochem. J. pmid:6517861
Schönfeld P et al. Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. 1984 Biomed. Biochim. Acta pmid:6525184
Allen PC and Danforth HD The effects of Eimeria acervulina infection on the metabolism of chick duodenal tissue. 1984 Vet. Parasitol. pmid:6538718
Mannaerts GP et al. Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. 1978 Biochim. Biophys. Acta pmid:656451
Herold G et al. Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. 1984 Biochim. Biophys. Acta pmid:6567470
Scholz R et al. The effect of fatty acids on the regulation of pyruvate dehydrogenase in perfused rat liver. 1978 Eur. J. Biochem. pmid:658055
Pösö AR and Mortimore GE Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6589593
Silavin SL et al. Reevaluation of the effects of cytochalasins on steroidogenesis: studies on hamster granulosa cells. 1984 Endocrinology pmid:6592092
Lagercrantz C and Larsson T Comparative studies of the binding of some ligands to human serum albumin non-covalently attached to immobilized Cibacron Blue, or covalently immobilized on Sepharose, by column affinity chromatography. 1983 Biochem. J. pmid:6615442
Martínez Izquierdo JA et al. Fatty acid-glucose interaction in the control of protein synthesis by isolated rat lung cells. 1983 Biochim. Biophys. Acta pmid:6615881
Abidova SS and Ovchinnikov IV [Effect of novodrin on fatty acid oxidation by the myocardial mitochondria of white rats]. 1983 Jul-Aug Farmakol Toksikol pmid:6617836
Spydevold O and Hokland B Release of leucine and isoleucine metabolites by perfused skeletal muscle and liver of rat. 1983 Int. J. Biochem. pmid:6617955
Bryła J and Niedzwiecka A The stimulatory effect of oleate on citrulline formation from carbamoyl phosphate and ornithine in rat-liver mitochondria: the relation to ornithine uptake. 1983 Int. J. Biochem. pmid:6617963
Ferré P et al. Development and regulation of ketogenesis in hepatocytes isolated from newborn rats. 1983 Biochem. J. pmid:6626164
Tangerman A et al. Quantitative determination of C2-C8 volatile fatty acids in human serum by vacuum distillation and gas chromatography. 1983 Clin. Chim. Acta pmid:6627690
Deaciuc IV et al. Studies on the mechanism of action of the hypoglycemic agent, 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). 1983 Biochem. Pharmacol. pmid:6651864
Russo C et al. Re.: Purification of IgG monoclonal antibody by caprylic acid precipitation. 1983 J. Immunol. Methods pmid:6655243
Bauché F et al. Inhibition in vitro of acyl-CoA dehydrogenases by 2-mercaptoacetate in rat liver mitochondria. 1983 Biochem. J. pmid:6661181
Parker WD et al. Effects of octanoate on rat brain and liver mitochondria. 1983 Neurology pmid:6684238
Pappas SC et al. Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. 1984 Gastroenterology pmid:6693016
Yu MW and Finlayson JS Quantitative determination of the stabilizers octanoic acid and N-acetyl-DL-tryptophan in human albumin products. 1984 J Pharm Sci pmid:6694090
Kohlwein SD and Paltauf F Uptake of fatty acids by the yeasts, Saccharomyces uvarum and Saccharomycopsis lipolytica. 1984 Biochim. Biophys. Acta pmid:6696936
Bell FP Di(2-ethylhexyl)adipate (DEHA): effect on plasma lipids and hepatic cholesterolgenesis in the rat. 1984 Bull Environ Contam Toxicol pmid:6697017
Nauclér J et al. Evaluation of kidney viability during hypothermic perfusion or cold storage. 1984 Eur Surg Res pmid:6698069
Thayer WS Inhibition of mitochondrial fatty acid oxidation in pentenoic acid-induced fatty liver. A possible model for Reye's syndrome. 1984 Biochem. Pharmacol. pmid:6712730
Otto DA Relationship of the ATP/ADP ratio to the site of octanoate activation. 1984 J. Biol. Chem. pmid:6715356
Habeeb AF and Francis RD Preparation of human immunoglobulin by caprylic acid precipitation. 1984 Prep. Biochem. pmid:6718324
Reed WD et al. A double-isotope method for the measurement of ketone-body turnover in the rat. Effect of L-alanine. 1984 Biochem. J. pmid:6721850
Soboll S et al. Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. 1984 Eur. J. Biochem. pmid:6723661
Aurousseau B et al. [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. 1984 Reprod Nutr Dev pmid:6729239
Chen V et al. Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. 1984 Horm. Metab. Res. pmid:6735347
Ross PD et al. Thermal stability of human albumin measured by differential scanning calorimetry. II. Effects of isomers of N-acetyltryptophanate and tryptophanate, pH, reheating, and dimerization. 1984 Vox Sang. pmid:6741029
Yu MW and Finlayson JS Stabilization of human albumin by caprylate and acetyltryptophanate. 1984 Vox Sang. pmid:6741030
Shrake A et al. Thermal stability of human albumin measured by differential scanning calorimetry. I. Effects of caprylate and N-acetyltryptophanate. 1984 Vox Sang. pmid:6741034
Soboll S et al. Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. 1984 Biochem. J. pmid:6743276
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Elliott JR et al. The asymmetrical effects of some ionized n-octyl derivatives on the sodium current of the giant axon of Loligo forbesi. 1984 J. Physiol. (Lond.) pmid:6747855
White RH Stable isotope studies on the biosynthesis of lipoic acid in Escherichia coli. 1980 Biochemistry pmid:6766313
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Chan SC Monitoring serum valproic acid by gas chromatography with electron-capture detection. 1980 Clin. Chem. pmid:6774836
Bijlsma R Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. 1980 Biochem. Genet. pmid:6781470
Derr RF and Zieve L Effect of fatty acids on the disposition of ammonia. 1976 J. Pharmacol. Exp. Ther. pmid:6789
Abbott FS et al. Valproic acid analysis in saliva and serum using selected ion monitoring (electron ionization) of the tert.-butyldimethylsilyl derivatives. 1982 J. Chromatogr. pmid:6801067
Palabost-Charles L Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster. 1982 Biochem. Genet. pmid:6810873
Buchowicz I et al. Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. 1981 Arch. Immunol. Ther. Exp. (Warsz.) pmid:6812541
Ledden DJ et al. Characterization of fragments of human albumin purified by Cibacron blue F3GA affinity chromatography. 1982 Biochem. J. pmid:6814424
Windus-Podehl G et al. Encephalopathic effect of phenol in rats. 1983 J. Lab. Clin. Med. pmid:6833829
Stange EF and Dietschy JM Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. 1983 J. Lipid Res. pmid:6833883
Zabłocki K et al. The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. 1983 Biochim. Biophys. Acta pmid:6838901
Almås I et al. The action of vasopressin and calcium on palmitate metabolism in hepatocytes and isolated mitochondria from rat liver. 1983 Arch. Biochem. Biophys. pmid:6847192
Werner JC et al. Fatty acid and glucose utilization in isolated, working newborn pig hearts. 1983 Am. J. Physiol. pmid:6849379
Latipää PM et al. Regulation of fatty acid oxidation in heart muscle. Effects of pyruvate and dichloroacetate. 1983 Biochim. Biophys. Acta pmid:6849964
Mayorek N and Bar-Tana J Medium chain fatty acids as specific substrates for diglyceride acyltransferase in cultured hepatocytes. 1983 J. Biol. Chem. pmid:6853505
Bell FP Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis. 1983 Lipids pmid:6855481
Rhead WJ et al. Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. 1983 Science pmid:6857268
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
Hjelmeland LM et al. A new class of nonionic detergents with a gluconamide polar group. 1983 Anal. Biochem. pmid:6869837
Pégorier JP et al. Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification. 1983 Biochem. J. pmid:6870859
Shapiro IM et al. Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcification. 1983 Biosci. Rep. pmid:6871381
Shimizu H [Comparative studies on perfused adult and fetal guinea pig liver metabolism before and after anoxia loadings, with special reference to intracellular redox state]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6875338
Rabinowitz JL et al. Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease. 1983 Lipids pmid:6877040
Bünger R et al. Energy utilization and pyruvate as determinants of pyruvate dehydrogenase in norepinephrine-stimulated heart. 1983 Pflugers Arch. pmid:6878010
Bagnasco SM et al. The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis. 1983 Metab. Clin. Exp. pmid:6888270
Caffier G et al. The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. 1980 Pflugers Arch. pmid:6966791
Kössler F et al. Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. 1980 Chem. Biol. Interact. pmid:6967777
Caffier G and Küchler G [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. 1980 Acta Biol. Med. Ger. pmid:6969509
Caffier G et al. Contractile properties of isolated frog skeletal muscles under the influence of Na-octanoate. 1982 Acta Biol. Med. Ger. pmid:6981273
Barth CA et al. Morphology and metabolism of adult rat hepatocytes in primary culture. 1980 Hoppe-Seyler's Z. Physiol. Chem. pmid:6997170
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Zwiebel FM et al. Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. 1982 Biochemistry pmid:7074018
Haidukewych D et al. Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet. 1982 Clin. Chem. pmid:7074833
Odessey R and Chace KV Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. 1982 Am. J. Physiol. pmid:7091374
Garcia-Esteller SC et al. Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo. 1982 Int. J. Biochem. pmid:7106360
Zeneroli ML et al. Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid. 1982 Sep-Oct Hepatology pmid:7118066