| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ruderman NB et al. | Effect of starvation on muscle glucose metabolism: studies with the isolated perfused rat hindquarter. | 1977 | Fed. Proc. | pmid:838085 |
| Hoffmann GF et al. | Physiology and pathophysiology of organic acids in cerebrospinal fluid. | 1993 | J. Inherit. Metab. Dis. | pmid:8412012 |
| Hossaini AA et al. | Experimental induction of caprylate-dependent albumin antibodies. | 1977 Jan-Feb | Transfusion | pmid:841674 |
| Miura S et al. | Increased proliferative response of lymphocytes from intestinal lymph during long chain fatty acid absorption. | 1993 | Immunology | pmid:8436400 |
| Reed KE and Cronan JE | Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes. | 1993 | J. Bacteriol. | pmid:8444795 |
| Grolier P and Elcombe CR | In vitro inhibition of carnitine acyltransferase activity in mitochondria from rat and mouse liver by a diethylhexylphthalate metabolite. | 1993 | Biochem. Pharmacol. | pmid:8452557 |
| Hayden MA et al. | Biosynthesis of lipoic acid: characterization of the lipoic acid auxotrophs Escherichia coli W1485-lip2 and JRG33-lip9. | 1993 | Biochemistry | pmid:8466915 |
| Mabayo RT et al. | Improvement of dietary protein utilisation in chicks by medium chain triglyceride. | 1993 | Br. Poult. Sci. | pmid:8467393 |
| Consoli A et al. | Limitations in the use of [2-14C]acetate for measuring gluconeogenesis in vivo. | 1993 | Diabetes | pmid:8482430 |
| Morand C et al. | Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. | 1993 | Am. J. Physiol. | pmid:8498503 |
| Liu MJ and Pollack GM | Pharmacokinetics and pharmacodynamics of valproate analogs in rats. II. Pharmacokinetics of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid. | 1993 | Biopharm Drug Dispos | pmid:8499583 |
| Ghoos YF et al. | Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. | 1993 | Gastroenterology | pmid:8500721 |
| Vandenvelde C et al. | Suppression of the inhibitory effect of denatured albumin on the polymerase chain reaction by sodium octanoate: application to routine clinical detection of hepatitis B virus at its infectivity threshold in serum. | 1993 | J. Virol. Methods | pmid:8514843 |
| Kuge Y et al. | Brain uptake and metabolism of [1-11C]octanoate in rats: pharmacokinetic basis for its application as a radiopharmaceutical for studying brain fatty acid metabolism. | 1995 | Ann Nucl Med | pmid:8534586 |
| Büllesbach EE and Schwabe C | Structural contribution of the A-chain loop in relaxin. | 1995 Sep-Oct | Int. J. Pept. Protein Res. | pmid:8537177 |
| Lamas JA et al. | Caprylic acid, a medium chain saturated fatty acid, inhibits the sodium inward current in neuroglioma (NG108-15) cells. | 1995 | Neurosci. Lett. | pmid:8552316 |
| Carrella M and Dietschy JM | Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat. | 1977 | Am J Dig Dis | pmid:857658 |
| Murphy MG et al. | Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy. | 1996 | Biochim. Biophys. Acta | pmid:8611661 |
| Perri F et al. | Gastric emptying and Helicobacter pylori infection in duodenal ulcer disease. | 1996 | Dig. Dis. Sci. | pmid:8617116 |
| Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
| Cheruvallath VK et al. | The effect of octanoic acid on the binding of the enantiomers of ibuprofen and naproxen to human serum albumin: a chromatographic implication. | 1996 | Pharm. Res. | pmid:8668670 |
| Tomita GM et al. | Antigenic crossreactivity and lipopolysaccharide neutralization properties of bovine immunoglobulin G. | 1995 | J. Dairy Sci. | pmid:8675757 |
| Sheikh MI et al. | On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. | 1978 | Arch. Int. Physiol. Biochim. | pmid:87158 |
| Planelles D et al. | A new, fast, and simple DNA extraction method for HLA and VNTR genotyping by PCR amplification. | 1996 | J. Clin. Lab. Anal. | pmid:8731498 |
| Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |
| Lin X et al. | Acetate represents a major product of heptanoate and octanoate beta-oxidation in hepatocytes isolated from neonatal piglets. | 1996 | Biochem. J. | pmid:8761477 |
| Barron JT et al. | Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. | 1996 | Am. J. Physiol. | pmid:8764234 |
| Zhou YP et al. | Inhibitory effects of fatty acids on glucose-regulated B-cell function: association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism. | 1996 | Metab. Clin. Exp. | pmid:8769356 |
| Godet MC et al. | Inclusion/exclusion of fatty acids in amylose complexes as a function of the fatty acid chain length. | 1995 | Int. J. Biol. Macromol. | pmid:8789347 |
| Guidry AJ and O'Brien CN | A method for measuring specific antibodies in bovine lacteal secretions during the nonlactating period. | 1996 | J. Dairy Sci. | pmid:8792284 |
| Priestman DA et al. | Pyruvate inhibition of pyruvate dehydrogenase kinase. Effects of progressive starvation and hyperthyroidism in vivo, and of dibutyryl cyclic AMP and fatty acids in cultured cardiac myocytes. | 1996 | FEBS Lett. | pmid:8814284 |
| Cave AC et al. | A model of anoxic preconditioning in the isolated rat cardiac myocyte. Importance of adenosine and insulin. | 1996 May-Jun | Basic Res. Cardiol. | pmid:8831940 |
| Petschow BW et al. | Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. | 1996 | Antimicrob. Agents Chemother. | pmid:8834870 |
| Veereman-Wauters G et al. | The 13C-octanoic acid breath test: a noninvasive technique to assess gastric emptying in preterm infants. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8856575 |
| Fulgencio JP et al. | Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats. | 1996 | Diabetes | pmid:8866561 |
| Bojes HK and Thurman RG | Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8887448 |
| Kalogeris TJ et al. | Intestinal synthesis and lymphatic secretion of apolipoprotein A-IV vary with chain length of intestinally infused fatty acids in rats. | 1996 | J. Nutr. | pmid:8914941 |
| Castel MA et al. | The antibodies causing thyroid stimulating hormone-binding inhibition (TSH-BI) are not responsible for the specific inhibition of gonadal steroidogenesis by Graves' sera. | 1996 | J. Reprod. Immunol. | pmid:8920164 |
| Katoh K et al. | Octanoate increases cytosolic Ca2+ concentration and membrane conductance in ovine pancreatic acinar cells. | 1996 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:8923746 |
| Guthy E | Enteric-coated fish oil in Crohn's disease. | 1996 | N. Engl. J. Med. | pmid:8927072 |
| Constantinides PP et al. | Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. | 1996 | Pharm. Res. | pmid:8932438 |
| Sidossis LS et al. | Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. | 1996 | J. Clin. Invest. | pmid:8941640 |
| Yang H et al. | Enhancing the stereoselectivity and activity of Candida species lipase in organic solvent by noncovalent enzyme modification. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8958099 |
| Kuge Y et al. | [1-11C]octanoate as a potential PET tracer for studying glial functions: PET evaluation in rats and cats. | 1996 | Nucl. Med. Biol. | pmid:9004290 |
| Yamazaki S et al. | Uptake of radioactive octanoate in astrocytoma cells: basic studies for application of [11C]octanoate as a PET tracer. | 1996 | Ann Nucl Med | pmid:9006724 |
| Trotter PJ et al. | Fatty acid uptake by Caco-2 human intestinal cells. | 1996 | J. Lipid Res. | pmid:9026531 |
| Bikhazi AB et al. | Calcium-prostaglandin aggregation and its effect on prostaglandin uptake by isolated rabbit intestine. | 1977 | J Pharm Sci | pmid:903871 |
| Viegas CA and Sá-Correia I | Effects of low temperatures (9-33 degrees C) and pH (3.3-5.7) in the loss of Saccharomyces cerevisiae viability by combining lethal concentrations of ethanol with octanoic and decanoic acids. | 1997 | Int. J. Food Microbiol. | pmid:9039572 |
| Priestman DA et al. | Inhibition of pyruvate dehydrogenase kinase by pyruvate in cultured cardiac myocytes. | 1997 | Biochem. Soc. Trans. | pmid:9056999 |
| Schadewaldt P et al. | Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS). | 1997 | Clin. Chem. | pmid:9068597 |
| Kunz D et al. | Flow cytometric detection of mitochondrial dysfunction in subpopulations of human mononuclear cells. | 1997 | Anal. Biochem. | pmid:9073359 |
| Choi MG et al. | [13C]octanoic acid breath test for gastric emptying of solids: accuracy, reproducibility, and comparison with scintigraphy. | 1997 | Gastroenterology | pmid:9097998 |
| Sen CK et al. | Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. | 1997 | Free Radic. Biol. Med. | pmid:9098099 |
| Amin D et al. | 1-Hydroxy-3-(methylpentylamino)-propylidene-1,1-bisphosphonic acid as a potent inhibitor of squalene synthase. | 1996 | Arzneimittelforschung | pmid:9125274 |
| Abdel-aleem S et al. | Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes. | 1997 | J. Mol. Cell. Cardiol. | pmid:9140835 |
| Pakula R et al. | Biosynthesis of medium-chain triacylglycerols and phospholipids by HepG-2 cells. | 1997 | Lipids | pmid:9168455 |
| Blatrix C et al. | [Properties of and information about a new preparation of immunoglobulins (IgGAM) enriched in IgA and IgM]. | 1977 | Rev. Fr. Transfus. Immunohematol. | pmid:918496 |
| Alcázar O et al. | Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid. | 1997 | Diabetes | pmid:9200650 |
| Maes BD et al. | Gastric emptying rate of solids in patients with nonulcer dyspepsia. | 1997 | Dig. Dis. Sci. | pmid:9201077 |
| Nakajima T et al. | The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. | 1997 | Pediatr. Res. | pmid:9212045 |
| Zaleski J and Bryla J | Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cells. | 1977 | Arch. Biochem. Biophys. | pmid:921276 |
| Jones JG et al. | Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. | 1997 | Anal. Biochem. | pmid:9212871 |
| Leclercq P et al. | Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. | 1997 | Biochem. J. | pmid:9230136 |
| Rabinowitz JL et al. | A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. | 1977 | Clin. Chem. | pmid:923071 |
| Coyle EF et al. | Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. | 1997 | Am. J. Physiol. | pmid:9277379 |
| Fowler JS et al. | Carbon-11 labeled aliphatic amines in lung uptake and metabolism studies: potential for dynamic measurements in vivo. | 1976 | J. Pharmacol. Exp. Ther. | pmid:933003 |
| Sheikh MI | Renal handling of phenol red. II. The mechanism of substituted phenolsulphophthalein (PSP) dye transport in rabbit kidney tubules in vitro. | 1976 | J. Physiol. (Lond.) | pmid:933027 |
| Bito LZ et al. | Inhibition of in vitro concentrative prostaglandin accumulation by prostaglandins, prostaglandin analogues and by some inhibitors of organic anion transport. | 1976 | J. Physiol. (Lond.) | pmid:933072 |
| Gann VK and Hardin CD | Acetate or octanoate increases glycogenolysis in smooth muscle as determined by 13C-NMR. | 1997 | Physiol Chem Phys Med NMR | pmid:9353955 |
| Chen TM et al. | Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. | 1997 | Am. J. Physiol. | pmid:9374750 |
| Andreev LV and Temnov AV | [Determination of the specificity of microbial esterases in vivo]. | 1976 Jan-Feb | Mikrobiologiia | pmid:940489 |
| Guillot E et al. | Octanoate metabolism in primary culture of chicken hepatocytes: evidence for high-capacity octanoate esterification. | 1997 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9440218 |
| Choi MG et al. | Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. | 1998 | Am. J. Gastroenterol. | pmid:9448183 |
| Barron JT et al. | Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. | 1997 | Biochim. Biophys. Acta | pmid:9452767 |
| Hillgartner FB and Charron T | Arachidonate and medium-chain fatty acids inhibit transcription of the acetyl-CoA carboxylase gene in hepatocytes in culture. | 1997 | J. Lipid Res. | pmid:9458278 |
| Viegas CA et al. | The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability. | 1998 | Appl. Environ. Microbiol. | pmid:9464423 |
| Visarius TM et al. | Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats. | 1998 | Drug Metab. Dispos. | pmid:9492379 |
| Groves CE et al. | Peritubular transport of ochratoxin A in rabbit renal proximal tubules. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9495853 |
| Sidossis LS et al. | Regulation of fatty acid oxidation in untrained vs. trained men during exercise. | 1998 | Am. J. Physiol. | pmid:9530135 |
| Abdel-aleem S et al. | Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia. | 1998 | Mol. Cell. Biochem. | pmid:9546635 |
| Maes BD et al. | 13C-Octanoic acid breath test for gastric emptying rate of solids. | 1998 | Gastroenterology | pmid:9547107 |
| Perri F et al. | 13C-Octanoic acid breath test: valueless test for gastric emptying? | 1998 | Gastroenterology | pmid:9547108 |
| De Boeck K et al. | Lipid digestion in cystic fibrosis: comparison of conventional and high-lipase enzyme therapy using the mixed-triglyceride breath test. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9552136 |
| Sibille B et al. | 2,4 Dinitrophenol-uncoupling effect on delta psi in living hepatocytes depends on reducing-equivalent supply. | 1998 | Cytometry | pmid:9627223 |
| Maes BD et al. | Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. | 1998 | Am. J. Physiol. | pmid:9655697 |
| Harper RD and Saggerson ED | Factors affecting fatty acid oxidation in fat cells isolated from rat white adipose tissue. | 1976 | J. Lipid Res. | pmid:965842 |
| Page M and Thorpe R | IgG purification. | 1998 | Methods Mol. Biol. | pmid:9664367 |
| Page M and Thorpe R | Purification of monoclonal antibodies. | 1998 | Methods Mol. Biol. | pmid:9664368 |
| Rabinowitz JL et al. | The effects of intravenous sodium octanoate on the rhesus monkey. | 1978 | Am. J. Gastroenterol. | pmid:96693 |
| Perri F et al. | 13C-octanoic acid breath test: a reliable tool for measuring gastric emptying. | 1998 | Ital J Gastroenterol Hepatol | pmid:9675662 |
| Jones CD | The genetic basis of Drosophila sechellia's resistance to a host plant toxin. | 1998 | Genetics | pmid:9691045 |
| Vinay P et al. | Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. | 1976 | Am. J. Physiol. | pmid:970471 |
| Yamamura N et al. | Evaluation of [1-11C]octanoate as a new radiopharmaceutical for assessing liver function using positron emission tomography. | 1998 | Nucl. Med. Biol. | pmid:9720664 |
| Bonen A et al. | Palmitate transport and fatty acid transporters in red and white muscles. | 1998 | Am. J. Physiol. | pmid:9725814 |
| Pailla K et al. | TNF-alpha and IL-6 synergistically inhibit ketogenesis from fatty acids and alpha-ketoisocaproate in isolated rat hepatocytes. | 1998 Sep-Oct | JPEN J Parenter Enteral Nutr | pmid:9739031 |
| Einarsson R | The binding of 1-anilino-8-naphthalenesulfonate, heparin, salicylate and caprylate by human antithrombin III. | 1976 | Biochim. Biophys. Acta | pmid:974107 |
| Leverve X et al. | Oxidative phosphorylation in intact hepatocytes: quantitative characterization of the mechanisms of change in efficiency and cellular consequences. | 1998 | Mol. Cell. Biochem. | pmid:9746312 |
| Decagny B et al. | 1H-NMR on line monitoring of water activity during lipase catalysed esterification. | 1998 | Biochim. Biophys. Acta | pmid:9748540 |
| Kawashima H et al. | Development of step-specific PET tracers for studying fatty acid beta-oxidation: biodistribution of [1-(11)C] octanoate analogs in rats and a cat. | 1998 | Nucl. Med. Biol. | pmid:9751421 |
| Yon JO et al. | Incorporation of extracellular phospholipids and their effect on the growth and lipid metabolism of the Saccharomyces cerevisiae cho1/pss mutant. | 1998 | Biochim. Biophys. Acta | pmid:9767089 |