octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
REES ED and KLINE DL Metabolism of octanoate by fatty liver slices. 1957 Am. J. Physiol. pmid:13470069
LOSSOW WJ and CHAIKOFF IL Secretion of intravenously administered tripalmitin-1-C14 and octanoate-1-C14 into milk by the lactating rat. 1958 J. Biol. Chem. pmid:13502382
DIANZANI MU and MARINARI U The octanoate oxidation by mitochondria from faty livers. 1961 Biochim. Biophys. Acta pmid:13722612
GLENN JL et al. Rare-earth fatty liver. I. Octanoate oxidation and energy production. 1962 Biochim. Biophys. Acta pmid:13899206
BROADBENT JL Importance of calcium in the actions of some drugs that stimulate the isolated hypodynamic frog heart. 1962 Br J Pharmacol Chemother pmid:13873208
PAYNE WJ and BANNISTER ER EFFECTS OF SODIUM CAPRYLATE ON CANDIDA ALBICANS. II. INFLUENCE OF VARIOUS CONCENTRATIONS ON BIOCHEMICAL CHANGES. 1963 J. Bacteriol. pmid:14066436
ADAMS JN et al. EFFECTS OF SODIUM CAPRYLATE ON CANDIDA ALBICANS. I. INFLUENCE OF CONCENTRATION ON ULTRASTRUCTURE. 1963 J. Bacteriol. pmid:14066435
BROADBENT JL THE INTERACTION OF SOME STIMULANT AND DEPRESSANT DRUGS ON THE FROG HEART. 1963 Br J Pharmacol Chemother pmid:14066153
GEHRIG RF and KNIGHT SG Fatty acid oxidation by spores of Penicillium roqueforti. 1963 Appl Microbiol pmid:13947000
SCHWABE AD et al. OCTANOIC ACID ABSORPTION AND OXIDATION IN HUMANS. 1964 J Appl Physiol pmid:14155309
KUSUNOSE M et al. ENZYMATIC OMEGA-OXIDATION OF FATTY ACIDS. I. PRODUCTS OF OCTANOATE, DECONATE, AND LAURATE OXIDATION. 1964 J. Biol. Chem. pmid:14189868
SMITH JA and DELUCA HF STRUCTURAL CHANGES IN ISOLATED LIVER MITOCHONDRIA OF RATS DURING ESSENTIAL FATTY ACID DEFICIENCY. 1964 J. Cell Biol. pmid:14154491
Clark SB The uptake of oleic acid by rat small intestine: a comparison of methodologies. 1971 J. Lipid Res. pmid:5542704
McGarry JD and Foster DW The regulation of ketogenesis from octanoic acid. The role of the tricarboxylic acid cycle and fatty acid synthesis. 1971 J. Biol. Chem. pmid:5543682
Abidov AA et al. [Strophantin K action on caprylate oxidation in the myocardium]. 1971 Sep-Oct Farmakol Toksikol pmid:5151251
Sallee VL et al. Determination of unidirectional uptake rates for lipids across the intestinal brush border. 1972 J. Lipid Res. pmid:5016300
Paquet RJ et al. Effects of thiamine deficiency and octanoate administration, in vivo, on gluconeogenesis in rat kidney slices and on amino acid profile in rat liver. 1972 Proc. Soc. Exp. Biol. Med. pmid:5039394
Sheikh MI Renal handling of phenol red. I. A comparative study on the accumulation of phenol red and p-aminohippurate in rabbit kidney tubules in vitro. 1972 J. Physiol. (Lond.) pmid:4647268
Aurousseau B and de Groot L [Effect of caprylic acid on metabolism of other fatty acids in the growing rat]. 1972 Ann Biol Anim Biochim Biophys pmid:4667618
Harwood JL et al. Fat metabolism in higher plants. Beta-hydroxylation of fatty acids by a soluble preparation from maturing avocado mesocarp. 1972 Biochem. J. pmid:4144293