| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tangen O et al. | Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. | 1975 | Scand. J. Clin. Lab. Invest. | pmid:1129590 |
| Clegg ME and Shafat A | Procedures in the 13C octanoic acid breath test for measurement of gastric emptying: analysis using Bland-Altman methods. | 2010 | Scand. J. Gastroenterol. | pmid:20443742 |
| Hope HB et al. | Reduced ¹³C-D-xylose absorption in alcoholics is more likely caused by alterations in small intestinal mucosa than delayed gastric emptying. | 2011 | Scand. J. Gastroenterol. | pmid:21275757 |
| Sugiyama E et al. | Desirable pharmacokinetic properties of (13)C-uracil as a breath test probe of gastric emptying in comparison with (13)C-acetate and (13)C-octanoate in rats. | 2009 | Scand. J. Gastroenterol. | pmid:19585373 |
| Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |
| Zimmermann S et al. | Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. | 2012 Jan-Mar | Sci Pharm | pmid:22396915 |
| Yamada M et al. | A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. | 2012 | Sci Rep | pmid:23226596 |
| Rhead WJ et al. | Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. | 1983 | Science | pmid:6857268 |
| Plante OJ et al. | Automated solid-phase synthesis of oligosaccharides. | 2001 | Science | pmid:11222853 |
| Ferreira BS et al. | A comparison of the physicochemical properties and fatty acid composition of indaiá (Attalea dubia) and Babassu (Orbignya phalerata) oils. | 2012 | ScientificWorldJournal | pmid:22593692 |
| Becerra-Dórame MJ et al. | Production response and digestive enzymatic activity of the Pacific white shrimp Litopenaeus vannamei (Boone, 1931) intensively pregrown in microbial heterotrophic and autotrophic-based systems. | 2012 | ScientificWorldJournal | pmid:22649317 |
| Kube M et al. | Current view on phytoplasma genomes and encoded metabolism. | 2012 | ScientificWorldJournal | pmid:22550465 |
| Kojima M and Kangawa K | [Structure and function of ghrelin]. | 2007 | Seikagaku | pmid:17969325 |
| Nikolic L et al. | Novel microwave-assisted synthesis of poly(D,L-lactide): the influence of monomer/initiator molar ratio on the product properties. | 2010 | Sensors (Basel) | pmid:22399924 |
| Koo KI et al. | Fabrication of a micro-fluid gathering tool for the gastrointestinal juice sampling function of a versatile capsular endoscope. | 2011 | Sensors (Basel) | pmid:22163997 |
| Zhao HZ et al. | [Production of functional lipids by lipase-catalyzed acidolysis of lard in solvent free system]. | 2005 | Sheng Wu Gong Cheng Xue Bao | pmid:16108382 |
| Zhou GW et al. | [Esterification of octanoic acid with 1-octanol catalyzed by lipase in W/O microemulsions and in microemulsion-based organogels]. | 2001 | Sheng Wu Gong Cheng Xue Bao | pmid:11411238 |
| Nash RA et al. | The possibility of lidocaine ion pair absorption through excised hairless mouse skin. | 1992 | Skin Pharmacol. | pmid:1445706 |
| Arivazhagan G et al. | Solute-solvent interactions of acid-1,4-dioxane mixtures-By dielectric, FTIR, UV-vis and 13C NMR spectrometric methods. | 2009 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:19775932 |
| Ivanova N et al. | Complete genome sequence of Gordonia bronchialis type strain (3410). | 2010 | Stand Genomic Sci | pmid:21304674 |
| Diard S et al. | Accumulation of poly(3-hydroxybutyrate) from octanoate in different pseudomonas belonging to the rRNA homology group I. | 2002 | Syst. Appl. Microbiol. | pmid:12353870 |
| Marquez A et al. | Optimization and validation of an automated DHS-TD-GC-MS method for the determination of aromatic esters in sweet wines. | 2014 | Talanta | pmid:24725861 |
| Hubert C et al. | Development and validation of a quantitative method for the selective determination of tin species in tin octoate by differential pulse polarography. | 2010 | Talanta | pmid:20006107 |
| Cabredo-Pinillos S et al. | Ultrasound-assisted extraction of volatile compounds from wine samples: optimisation of the method. | 2006 | Talanta | pmid:18970692 |
| Jha SK and Hayashi K | A quick responding quartz crystal microbalance sensor array based on molecular imprinted polyacrylic acids coating for selective identification of aldehydes in body odor. | 2015 | Talanta | pmid:25618646 |
| Dawson DA | Additive incidence of developmental malformation for Xenopus embryos exposed to a mixture of ten aliphatic carboxylic acids. | 1991 | Teratology | pmid:1771595 |
| Klammt S et al. | Increase of octanoate concentrations during extracorporeal albumin dialysis treatments. | 2009 | Ther Apher Dial | pmid:19788462 |
| Wood P | Human normal immunoglobulin in the treatment of primary immunodeficiency diseases. | 2012 | Ther Clin Risk Manag | pmid:22547934 |
| Terai S et al. | Lack of modulation of gastric emptying by dietary nitrate in healthy volunteers. | 2009 | Tohoku J. Exp. Med. | pmid:19398876 |
| Saito K et al. | An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | 2017 | Toxicol In Vitro | pmid:27965148 |
| Hoffmann J et al. | Epidermal-skin-test 1,000 (EST-1,000)--a new reconstructed epidermis for in vitro skin corrosivity testing. | 2005 | Toxicol In Vitro | pmid:16061350 |
| Nau H et al. | Pharmacokinetic aspects of drug effects in vitro (II) placental transfer to the embryo and activity of some carboxylic acids structurally related to valproic acid in whole embryos in culture. | 1988 | Toxicol In Vitro | pmid:20702331 |
| Zurich MG et al. | Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | 2013 | Toxicol In Vitro | pmid:22954530 |
| Kiang TK et al. | Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21397622 |
| Bojes HK and Thurman RG | Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8887448 |
| Hernández-Esquivel L et al. | Cardiotoxicity of copper-based antineoplastic drugs casiopeinas is related to inhibition of energy metabolism. | 2006 | Toxicol. Appl. Pharmacol. | pmid:16051288 |
| Vanden Heuvel JP et al. | Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. | 2006 | Toxicol. Sci. | pmid:16731579 |
| Nudel BC et al. | Optimization by factorial analysis of caprylic acid precipitation of non-immunoglobulins from hyperimmune equine plasma for antivenom preparation. | 2012 | Toxicon | pmid:22079738 |
| dos Santos MC et al. | Purification of F(ab')2 anti-snake venom by caprylic acid: a fast method for obtaining IgG fragments with high neutralization activity, purity and yield. | 1989 | Toxicon | pmid:2728022 |
| León G et al. | Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols. | 2005 | Toxicon | pmid:15581691 |
| Herrera M et al. | Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs. | 2005 | Toxicon | pmid:16183094 |
| Rojas G et al. | Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. | 1994 | Toxicon | pmid:8016856 |
| Otero-Patiño R et al. | Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. | 2012 | Toxicon | pmid:22146491 |
| Otero R et al. | A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms. | 1999 | Toxicon | pmid:10340829 |
| Eursakun S et al. | Studies on the fractionation of equine antivenom IgG by combinations of ammonium sulfate and caprylic acid. | 2012 | Toxicon | pmid:22842065 |
| Frauches TS et al. | Bothropic antivenom based on monoclonal antibodies, is it possible? | 2013 | Toxicon | pmid:23732123 |
| Segura A et al. | Stability of equine IgG antivenoms obtained by caprylic acid precipitation: towards a liquid formulation stable at tropical room temperature. | 2009 | Toxicon | pmid:19673074 |
| Fernández GP et al. | Neutralization of Bothrops mattogrossensis snake venom from Bolivia: experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation. | 2010 Feb-Mar | Toxicon | pmid:19647761 |
| Theakston RD et al. | Report of a WHO workshop on the standardization and control of antivenoms. | 2003 | Toxicon | pmid:12676433 |
| Anzai N et al. | Molecular mechanism of ochratoxin a transport in the kidney. | 2010 | Toxins (Basel) | pmid:22069643 |