| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vauhkonen M and Somerharju P | Parinaroyl and pyrenyl phospholipids as probes for the lipid surface layer of human low density lipoproteins. | 1989 | Biochim. Biophys. Acta | pmid:2765542 |
| Sumbilla CM et al. | Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:7272339 |
| Einarsson R | The binding of 1-anilino-8-naphthalenesulfonate, heparin, salicylate and caprylate by human antithrombin III. | 1976 | Biochim. Biophys. Acta | pmid:974107 |
| Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
| Tachibana S et al. | Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes. | 2005 | Biochim. Biophys. Acta | pmid:16226916 |
| Dorset DL | Co-solubility of saturated cholesteryl esters: a comparison of calculated and experimental binary phase diagrams. | 1988 | Biochim. Biophys. Acta | pmid:3179332 |
| Arakawa T and Kita Y | Stabilizing effects of caprylate and acetyltryptophanate on heat-induced aggregation of bovine serum albumin. | 2000 | Biochim. Biophys. Acta | pmid:10862953 |
| Merrill AR et al. | Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. | 1986 | Biochim. Biophys. Acta | pmid:3081028 |
| Veerkamp JH et al. | An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. | 1986 | Biochim. Biophys. Acta | pmid:3081042 |
| GLENN JL et al. | Rare-earth fatty liver. I. Octanoate oxidation and energy production. | 1962 | Biochim. Biophys. Acta | pmid:13899206 |
| Barron JT et al. | Effect of serum albumin on vascular smooth muscle metabolism. | 2000 | Biochim. Biophys. Acta | pmid:10924897 |
| DIANZANI MU and MARINARI U | The octanoate oxidation by mitochondria from faty livers. | 1961 | Biochim. Biophys. Acta | pmid:13722612 |
| Herold G et al. | Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. | 1984 | Biochim. Biophys. Acta | pmid:6567470 |
| Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
| Gambert S et al. | Regulation of intermediary metabolism in rat cardiac myocyte by extracellular glycerol. | 2005 | Biochim. Biophys. Acta | pmid:16153888 |
| Müller MJ et al. | Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. | 1981 | Biochim. Biophys. Acta | pmid:6275888 |
| Anraku M et al. | Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress. | 2004 | Biochim. Biophys. Acta | pmid:15450846 |
| Hulsmann WC et al. | Imminent ischemia in normal and hypertrophic Langendorff rat hearts; effects of fatty acids and superoxide dismutase monitored by NADH surface fluorescence. | 1993 | Biochim. Biophys. Acta | pmid:8318552 |
| Viegas CA et al. | Regulation of the expression of the H(+)-ATPase genes PMA1 and PMA2 during growth and effects of octanoic acid in Saccharomyces cerevisiae. | 1994 | Biochim. Biophys. Acta | pmid:8286419 |
| Murphy MG et al. | Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy. | 1996 | Biochim. Biophys. Acta | pmid:8611661 |
| Decagny B et al. | 1H-NMR on line monitoring of water activity during lipase catalysed esterification. | 1998 | Biochim. Biophys. Acta | pmid:9748540 |
| Thennarasu S et al. | Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843. | 2005 | Biochim. Biophys. Acta | pmid:15904663 |
| González-Manchón C et al. | Ca2(+)-fatty acid interaction in the control of hepatic gluconeogenesis. | 1990 | Biochim. Biophys. Acta | pmid:2310772 |
| Salesse R and Garnier J | Effects of drugs on pigeon erythrocyte membrane and asymmetric control or adenylate cyclase by the lipid bilayer. | 1979 | Biochim. Biophys. Acta | pmid:222319 |
| Magliano P et al. | Repercussion of a deficiency in mitochondrial ß-oxidation on the carbon flux of short-chain fatty acids to the peroxisomal ß-oxidation cycle in Aspergillus nidulans. | 2010 | Biochim. Biophys. Acta | pmid:20736083 |
| Shimshoni JA et al. | Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder. | 2011 | Biochim. Biophys. Acta | pmid:21184843 |
| Nomura T et al. | Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. | 1983 | Biochim. Biophys. Acta | pmid:6317044 |
| Bohnensack R and Fritz S | Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model. | 1991 | Biochim. Biophys. Acta | pmid:2009283 |
| Salesse R et al. | [Intensity and anisotropy decays measurement of perylene in pigeon erythrocyte membrane. Comparison with an isotropic viscous medium (author's transl)]. | 1981 Nov-Dec | Biochimie | pmid:7332761 |
| Pérez-Diaz J et al. | Preparation and metabolic characterization of isolated rat lung cells. | 1977 | Biochimie | pmid:195638 |
| Pochapsky SS et al. | Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. | 1990 Jul-Aug | Bioconjug. Chem. | pmid:2096916 |
| van Ginkel CG et al. | Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. | 2008 | Biodegradation | pmid:17492358 |
| Goussen C et al. | Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. | 2017 | BioDrugs | pmid:28508264 |
| Nagata J et al. | Effects of structured lipids containing eicosapentaenoic or docosahexaenoic acid and caprylic acid on serum and liver lipid profiles in rats. | 2004 | Biofactors | pmid:15630273 |
| Kundu S and Roy D | Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. | 2010 | Bioinformation | pmid:20978606 |
| Kumar S | Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. | 2011 | Bioinformation | pmid:22355237 |
| Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
| Lemmen C et al. | Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts. | 1988 | Biol. Chem. Hoppe-Seyler | pmid:3242549 |
| Küster J et al. | Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. | 1989 | Biol. Chem. Hoppe-Seyler | pmid:2692615 |
| Kuge Y et al. | [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. | 2000 | Biol. Pharm. Bull. | pmid:10963308 |
| Tokudome Y and Otsuka M | Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. | 2012 | Biol. Pharm. Bull. | pmid:22975500 |
| Uchida M and Shimizu K | 13C-acetic acid is more sensitive than 13C-octanoic acid for evaluating gastric emptying of liquid enteral nutrient formula by breath test in conscious rats. | 2007 | Biol. Pharm. Bull. | pmid:17329843 |
| Barnette D et al. | Pathogen safety profile of a 10% IgG preparation manufactured using a depth filtration-modified process. | 2012 | Biologicals | pmid:22579294 |
| Solano S et al. | Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. | 2012 | Biologicals | pmid:22266304 |
| Johnston A et al. | Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. | 2003 | Biologicals | pmid:12935811 |
| Estrada R et al. | Intravenous administration of equine-derived whole IgG antivenom does not induce early adverse reactions in non-envenomed horses and cows. | 2010 | Biologicals | pmid:20833066 |
| Segura A et al. | Assessment of the impact of solvent/detergent treatment on the quality and potency of a whole IgG equine antivenom. | 2009 | Biologicals | pmid:19540775 |
| Stucki M et al. | Investigations of prion and virus safety of a new liquid IVIG product. | 2008 | Biologicals | pmid:18337119 |
| Mpandi M et al. | Partitioning and inactivation of viruses by the caprylic acid precipitation followed by a terminal pasteurization in the manufacturing process of horse immunoglobulins. | 2007 | Biologicals | pmid:17470396 |
| Burnouf T et al. | Assessment of viral inactivation during pH 3.3 pepsin digestion and caprylic acid treatment of antivenoms. | 2007 | Biologicals | pmid:17363271 |
| Simsiriwong P et al. | A study on the use of caprylic acid and ammonium sulfate in combination for the fractionation of equine antivenom F(ab')(2). | 2012 | Biologicals | pmid:22704919 |
| Burnouf T et al. | Assessment of the viral safety of antivenoms fractionated from equine plasma. | 2004 | Biologicals | pmid:15536042 |
| Herrera M et al. | Development and validation of a reverse phase HPLC method for the determination of caprylic acid in formulations of therapeutic immunoglobulins and its application to antivenom production. | 2009 | Biologicals | pmid:19375941 |
| Athavale M et al. | Validation of a simple, rapid and cost effective method for the estimation of caprylic acid and sodium caprylate from biological products using NEFA-C kit. | 2010 | Biologicals | pmid:19919899 |
| GarcÃa M et al. | Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. | 2002 | Biologicals | pmid:12127316 |
| Korneyeva M et al. | Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates. | 2002 | Biologicals | pmid:12127317 |
| Dichtelmüller H et al. | Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. | 2002 | Biologicals | pmid:12127315 |
| Corbin PS et al. | Biocompatible polyester macroligands: new subunits for the assembly of star-shaped polymers with luminescent and cleavable metal cores. | 2001 | Biomacromolecules | pmid:11749177 |
| Cheng Y et al. | Thermally controlled release of anticancer drug from self-assembled γ-substituted amphiphilic poly(ε-caprolactone) micellar nanoparticles. | 2012 | Biomacromolecules | pmid:22681332 |
| Wang CH et al. | Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel. | 2012 | Biomacromolecules | pmid:22145634 |
| Randriamahefa S et al. | Fourier transform infrared spectroscopy for screening and quantifying production of PHAs by Pseudomonas grown on sodium octanoate. | 2003 Jul-Aug | Biomacromolecules | pmid:12857097 |
| Rai R et al. | Poly-3-hydroxyoctanoate P(3HO), a medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina. | 2011 | Biomacromolecules | pmid:21561067 |
| Hartmann R et al. | Simultaneous biosynthesis of two copolymers in Pseudomonas putida GPo1 using a two-stage continuous culture system. | 2010 | Biomacromolecules | pmid:20459087 |
| Mahmud A et al. | Self-associating poly(ethylene oxide)-b-poly(alpha-cholesteryl carboxylate-epsilon-caprolactone) block copolymer for the solubilization of STAT-3 inhibitor cucurbitacin I. | 2009 | Biomacromolecules | pmid:19175305 |
| Karanikolopoulos N et al. | Poly(DL-lactide)-b-poly(N,N-dimethylamino-2-ethyl methacrylate): synthesis, characterization, micellization behavior in aqueous solutions, and encapsulation of the hydrophobic drug dipyridamole. | 2010 | Biomacromolecules | pmid:20041661 |
| Buwalda SJ et al. | Influence of amide versus ester linkages on the properties of eight-armed PEG-PLA star block copolymer hydrogels. | 2010 | Biomacromolecules | pmid:19938809 |
| Wang YC et al. | Thermoresponsive block copolymers of poly(ethylene glycol) and polyphosphoester: thermo-induced self-assembly, biocompatibility, and hydrolytic degradation. | 2009 | Biomacromolecules | pmid:19133835 |
| Du JZ et al. | Synthesis and characterization of photo-cross-linked hydrogels based on biodegradable polyphosphoesters and poly(ethylene glycol) copolymers. | 2007 | Biomacromolecules | pmid:17902689 |
| Tsuji H et al. | Novel preparation method for poly(L-lactide)-based block copolymers: extended chain crystallites as a solid-state macro-coinitiator. | 2007 | Biomacromolecules | pmid:17432901 |
| Haynes D et al. | In situ copolyesters containing poly(L-lactide) and poly(hydroxyalkanoate) units. | 2007 | Biomacromolecules | pmid:17371065 |
| Dai XH et al. | Supramolecular Polypseudorotaxanes composed of star-shaped porphyrin-cored poly(epsilon-caprolactone) and alpha-cyclodextrin. | 2006 | Biomacromolecules | pmid:17154484 |
| Gerhardt WW et al. | Functional lactide monomers: methodology and polymerization. | 2006 | Biomacromolecules | pmid:16768392 |
| Jiang X et al. | Biosynthesis and properties of medium-chain-length polyhydroxyalkanoates with enriched content of the dominant monomer. | 2012 | Biomacromolecules | pmid:22871146 |
| Kricheldorf HR and Rost S | Copolymerizations of epsilon-caprolactone and glycolide-a comparison of tin(II)octanoate and bismuth(III)subsalicylate as initiators. | Biomacromolecules | pmid:15877351 | |
| Qiu X et al. | Hydroxyapatite surface modified by L-lactic acid and its subsequent grafting polymerization of L-lactide. | Biomacromolecules | pmid:15877333 | |
| Dobrzynski P et al. | Structure-property relationships of copolymers obtained by ring-opening polymerization of glycolide and epsilon-caprolactone. Part 1. Synthesis and characterization. | Biomacromolecules | pmid:15638556 | |
| Hu Y et al. | Degradation behavior of poly(epsilon-caprolactone)-b-poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles in aqueous solution. | Biomacromolecules | pmid:15360284 | |
| Sanguanchaipaiwong V et al. | Biosynthesis of natural-synthetic hybrid copolymers: polyhydroxyoctanoate-diethylene glycol. | Biomacromolecules | pmid:15003032 | |
| Gorenflo V et al. | Development of a process for the biotechnological large-scale production of 4-hydroxyvalerate-containing polyesters and characterization of their physical and mechanical properties. | 2001 | Biomacromolecules | pmid:11749154 |
| Ba C et al. | Syntheses and physical characterization of new aliphatic triblock poly(L-lactide-b-butylene succinate-b-L-lactide)s bearing soft and hard biodegradable building blocks. | Biomacromolecules | pmid:14606915 | |
| Gomes FM et al. | Immobilization of lipase on chitin and its use in nonconventional biocatalysis. | 2004 Jan-Feb | Biomacromolecules | pmid:14715003 |
| Choi MH et al. | First-order kinetics analysis of monomer composition dependent polyhydroxyalkanoic acid degradation in Pseudomonas spp. | Biomacromolecules | pmid:12625741 | |
| Green PR et al. | Formation of short chain length/medium chain length polyhydroxyalkanoate copolymers by fatty acid beta-oxidation inhibited Ralstonia eutropha. | 2002 Jan-Feb | Biomacromolecules | pmid:11866575 |
| Ou W et al. | Biodegradable block poly(ester-urethane)s based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymers. | 2011 | Biomaterials | pmid:21310479 |
| Kubies D et al. | Microdomain structure in polylactide-block-poly(ethylene oxide) copolymer films. | 2000 | Biomaterials | pmid:10674818 |
| Pan J et al. | Alternative block polyurethanes based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(ethylene glycol). | 2009 | Biomaterials | pmid:19230967 |
| Patel SK et al. | Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. | 2010 | Biomaterials | pmid:19796808 |
| Zhou S et al. | Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) block copolymers: characterization and their use as drug carriers for a controlled delivery system. | 2003 | Biomaterials | pmid:12809785 |
| Cai Q et al. | Synthesis and characterization of biodegradable polylactide-grafted dextran and its application as compatilizer. | 2003 | Biomaterials | pmid:12809784 |
| Hazer DB et al. | Synthesis of microbial elastomers based on soybean oily acids. Biocompatibility studies. | 2009 | Biomed Mater | pmid:19498224 |
| Alva-Murillo N et al. | Effects of sodium octanoate on innate immune response of mammary epithelial cells during Staphylococcus aureus internalization. | 2013 | Biomed Res Int | pmid:23509807 |
| Haufe CC et al. | Development and regulation of hepatocellular fatty acid synthesis towards term: studies in isolated fetal rat hepatocytes. | 1990 | Biomed. Biochim. Acta | pmid:2177982 |
| Kössler F et al. | Depressive effects of free fatty acids on the development of tension in different muscle types. | 1986 | Biomed. Biochim. Acta | pmid:2938577 |
| Schönfeld P et al. | Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. | 1984 | Biomed. Biochim. Acta | pmid:6525184 |
| Letko G and Halangk W | Effect of improved hydrogen supply on energy state, ureogenesis and gluconeogenesis in isolated hepatocytes. | 1986 | Biomed. Biochim. Acta | pmid:3707550 |
| Santa T et al. | Synthesis of benzofurazan derivatization reagents for carboxylic acids in liquid chromatography/electrospray ionization-tandem mass spectrometry. | 2007 | Biomed. Chromatogr. | pmid:17590866 |
| Kuhara T et al. | Identification and quantification of octanoyl glucuronide in the urine of children who ingested medium-chain triglycerides. | 1986 | Biomed. Environ. Mass Spectrom. | pmid:2948585 |
| Nakajima K et al. | Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. | 2016 | Biomed. Res. | pmid:28003581 |
| Hainaut J et al. | Differentiation of antilymphocytic antibodies by analytical ion exchange chromatography: the effect of caprylic acid. | 1974 | Biomedicine | pmid:4433656 |
| Koda Y et al. | Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. | 2008 | Bioorg. Med. Chem. | pmid:18468445 |