| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Eye Burns | D005126 | 13 associated lipids |
| Cardiomegaly | D006332 | 31 associated lipids |
| Heart Injuries | D006335 | 6 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
n-heptanol
N-heptanol is a lipid of Fatty Acyls (FA) class. N-heptanol is associated with abnormalities such as Corneal Neovascularization. N-heptanol often locates in Epithelium and Structure of corneal epithelium. The related lipids are Heptanol.
Cross Reference
Introduction
To understand associated biological information of n-heptanol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with n-heptanol?
n-heptanol is suspected in Corneal Neovascularization and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with n-heptanol
PubChem Associated disorders and diseases
What pathways are associated with n-heptanol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with n-heptanol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with n-heptanol?
There are no associated biomedical information in the current reference collection.
What lipids are associated with n-heptanol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with n-heptanol?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with n-heptanol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with n-heptanol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zada A et al. | Synthesis and biological activity of the four stereoisomers of 4-methyl-3-heptanol: main component of the aggregation pheromone of Scolytus amygdali. | 2004 | J. Chem. Ecol. | pmid:15139313 |
| Saïd I et al. | Interactions between acetoin, a plant volatile, and pheromone in Rhynchophorus palmarum: behavioral and olfactory neuron responses. | 2005 | J. Chem. Ecol. | pmid:16222808 |
| Cossé AA et al. | The aggregation pheromone of Diorhabda elongata, a biological control agent of saltcedar (Tamarix spp.): identification of two behaviorally active components. | 2005 | J. Chem. Ecol. | pmid:15898507 |
| Oehlschlager AC et al. | Pheromone-based trapping of West Indian sugarcane weevil in a sugarcane plantation. | 2002 | J. Chem. Ecol. | pmid:12371817 |
| Eksborg S et al. | Liquid chromatographic determination of daunorubicin and daunorubicinol in plasma from leukemic patients. | 1978 | J. Chromatogr. | pmid:659557 |
| Jackman GP et al. | Simple and sensitive procedure for the assay of serotonin and catecholamines in brain by high-performance liquid chromatography using fluorescence detection. | 1980 | J. Chromatogr. | pmid:7391168 |
| Kuebler WM et al. | A novel signaling mechanism between gas and blood compartments of the lung. | 2000 | J. Clin. Invest. | pmid:10749570 |
| Meda P et al. | Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells. | 1990 | J. Clin. Invest. | pmid:1697604 |
| Reed KE et al. | Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. | 1993 | J. Clin. Invest. | pmid:7680674 |
| Johnson BA et al. | Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb. | 2005 | J. Comp. Neurol. | pmid:15678475 |
| Schorkopf DL et al. | Mandibular gland secretions of meliponine worker bees: further evidence for their role in interspecific and intraspecific defence and aggression and against their role in food source signalling. | 2009 | J. Exp. Biol. | pmid:19329748 |
| Laska M and Seibt A | Olfactory sensitivity for aliphatic alcohols in squirrel monkeys and pigtail macaques. | 2002 | J. Exp. Biol. | pmid:12000808 |
| Miyasaki T et al. | Change of volatile compounds in fresh fish meat during ice storage. | 2011 Nov-Dec | J. Food Sci. | pmid:22416694 |
| Tsai ML et al. | The role of gap junctional communication in contractile oscillations in arteries from normotensive and hypertensive rats. | 1995 | J. Hypertens. | pmid:8586804 |
| Matsue H et al. | Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs. | 2006 | J. Immunol. | pmid:16365409 |
| Gu D and Yang DR | Utilisation of chemical signals by inquiline wasps in entering their host figs. | 2013 | J. Insect Physiol. | pmid:23973817 |
| Karvonen SL et al. | Psoriasis and altered calcium metabolism: downregulated capacitative calcium influx and defective calcium-mediated cell signaling in cultured psoriatic keratinocytes. | 2000 | J. Invest. Dermatol. | pmid:10733675 |
| Le Lay S et al. | Caveolin-1-dependent and -independent membrane domains. | 2009 | J. Lipid Res. | pmid:19074371 |
| Desplantez T et al. | Influence of v5/6-His tag on the properties of gap junction channels composed of connexin43, connexin40 or connexin45. | 2011 | J. Membr. Biol. | pmid:21424225 |
| Peracchia C | Effects of the anesthetics heptanol, halothane and isoflurane on gap junction conductance in crayfish septate axons: a calcium- and hydrogen-independent phenomenon potentiated by caffeine and theophylline, and inhibited by 4-aminopyridine. | 1991 | J. Membr. Biol. | pmid:2051474 |
| Délèze J and Hervé JC | Quantitative gap junction alterations in mammalian heart cells quickly frozen or chemically fixed after electrical uncoupling. | 1986 | J. Membr. Biol. | pmid:3795259 |
| Bastiaanse EM et al. | Heptanol-induced decrease in cardiac gap junctional conductance is mediated by a decrease in the fluidity of membranous cholesterol-rich domains. | 1993 | J. Membr. Biol. | pmid:7508980 |
| Délèze J and Hervé JC | Effect of several uncouplers of cell-to-cell communication on gap junction morphology in mammalian heart. | 1983 | J. Membr. Biol. | pmid:6887233 |
| Praetorius HA and Spring KR | Bending the MDCK cell primary cilium increases intracellular calcium. | 2001 | J. Membr. Biol. | pmid:11687880 |
| Julák J et al. | Bronchoalveolar lavage examined by solid phase microextraction, gas chromatography--mass spectrometry and selected ion flow tube mass spectrometry. | 2006 | J. Microbiol. Methods | pmid:16048732 |
| Shapira-Schweitzer K et al. | A photopolymerizable hydrogel for 3-D culture of human embryonic stem cell-derived cardiomyocytes and rat neonatal cardiac cells. | 2009 | J. Mol. Cell. Cardiol. | pmid:19027751 |
| Jiao Z et al. | A possible mechanism of halocarbon-induced cardiac sensitization arrhythmias. | 2006 | J. Mol. Cell. Cardiol. | pmid:16919292 |
| Diederichs F | Protection of isolated rat heart against the Ca2+ paradox. Are gap junction channels involved? | 1995 | J. Mol. Cell. Cardiol. | pmid:8531212 |
| Li F et al. | Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition. | 2001 | J. Mol. Cell. Cardiol. | pmid:11735261 |
| Kim HW et al. | Stem cell-based delivery of Hypoxamir-210 to the infarcted heart: implications on stem cell survival and preservation of infarcted heart function. | 2012 | J. Mol. Med. | pmid:22648522 |
| Lee KK et al. | Isolation and structure elucidation of new PKCalpha inhibitors from Pinus flexilis. | 1998 | J. Nat. Prod. | pmid:9834165 |
| Aitken PG et al. | Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically. | 1998 | J. Neurophysiol. | pmid:9744955 |
| Largo C et al. | Heptanol but not fluoroacetate prevents the propagation of spreading depression in rat hippocampal slices. | 1997 | J. Neurophysiol. | pmid:9120600 |
| Solomon IC et al. | Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat. | 2003 | J. Neurophysiol. | pmid:12522166 |
| Rekling JC et al. | Electrical coupling and excitatory synaptic transmission between rhythmogenic respiratory neurons in the preBötzinger complex. | 2000 | J. Neurosci. | pmid:11090613 |
| Saint-Amant L and Drapeau P | Motoneuron activity patterns related to the earliest behavior of the zebrafish embryo. | 2000 | J. Neurosci. | pmid:10818131 |
| Carrow GM and Levitan IB | Selective formation and modulation of electrical synapses between cultured Aplysia neurons. | 1989 | J. Neurosci. | pmid:2795146 |
| Suadicani SO et al. | P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. | 2006 | J. Neurosci. | pmid:16452661 |
| McLarnon JG and Quastel DM | Thermodynamic parameters of end-plate channel blockade. | 1984 | J. Neurosci. | pmid:6325608 |
| Ye ZC et al. | Functional hemichannels in astrocytes: a novel mechanism of glutamate release. | 2003 | J. Neurosci. | pmid:12736329 |
| Scemes E et al. | Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation. | 2000 | J. Neurosci. | pmid:10662834 |
| Hong T et al. | Inhibitory effect of gap junction blockers on cerebral vasospasm. | 2008 | J. Neurosurg. | pmid:18312103 |
| Przyklenk K et al. | Pretreatment with D-myo-inositol trisphosphate reduces infarct size in rabbit hearts: role of inositol trisphosphate receptors and gap junctions in triggering protection. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15919762 |
| Shiraishi M and Harris RA | Effects of alcohols and anesthetics on recombinant voltage-gated Na+ channels. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14978193 |
| Christ GJ et al. | Gap junctions modulate tissue contractility and alpha 1 adrenergic agonist efficacy in isolated rat aorta. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8102641 |
| Sessoms-Sikes JS et al. | A mutation in transmembrane domain II of the 5-hydroxytryptamine(3A) receptor stabilizes channel opening and alters alcohol modulatory actions. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12730353 |
| Lissi EA and Rosenbluth H | Disruption effects of carbon tetrachloride on rat liver microsomes. | 1993 | J. Photochem. Photobiol. B, Biol. | pmid:8433221 |
| Boehmer G et al. | Subthreshold oscillation of the membrane potential in magnocellular neurones of the rat supraoptic nucleus. | 2000 | J. Physiol. (Lond.) | pmid:10878105 |
| Rodriguez-Sinovas A et al. | Enhanced effect of gap junction uncouplers on macroscopic electrical properties of reperfused myocardium. | 2004 | J. Physiol. (Lond.) | pmid:15218064 |
| Murrell RD et al. | Actions of n-alcohols on nicotinic acetylcholine receptor channels in cultured rat myotubes. | 1991 | J. Physiol. (Lond.) | pmid:1890643 |
| Bukauskas F et al. | Electrical coupling between cells of the insect Aedes albopictus. | 1992 | J. Physiol. (Lond.) | pmid:1593470 |
| Nygren A et al. | Propagation of the cardiac impulse in the diabetic rat heart: reduced conduction reserve. | 2007 | J. Physiol. (Lond.) | pmid:17185336 |
| Chilton L et al. | Evidence of intercellular coupling between co-cultured adult rabbit ventricular myocytes and myofibroblasts. | 2007 | J. Physiol. (Lond.) | pmid:17569734 |
| Hennig GW et al. | Patterns of intracellular and intercellular Ca2+ waves in the longitudinal muscle layer of the murine large intestine in vitro. | 2002 | J. Physiol. (Lond.) | pmid:12181295 |
| Delmar M et al. | Effects of changes in excitability and intercellular coupling on synchronization in the rabbit sino-atrial node. | 1986 | J. Physiol. (Lond.) | pmid:3958977 |
| McHale NG and Meharg MK | Co-ordination of pumping in isolated bovine lymphatic vessels. | 1992 | J. Physiol. (Lond.) | pmid:1432715 |
| Jalife J | Mutual entrainment and electrical coupling as mechanisms for synchronous firing of rabbit sino-atrial pace-maker cells. | 1984 | J. Physiol. (Lond.) | pmid:6097670 |
| Li WC et al. | Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles. | 2009 | J. Physiol. (Lond.) | pmid:19221124 |
| Chaytor AT et al. | Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteries. | 1997 | J. Physiol. (Lond.) | pmid:9288678 |
| Manchanda R and Venkateswarlu K | Quantal evoked depolarizations underlying the excitatory junction potential of the guinea-pig isolated vas deferens. | 1999 | J. Physiol. (Lond.) | pmid:10523420 |
| Roche A and Joffre M | Effect of uncoupling treatments on FSH-induced hyperpolarization of immature rat Sertoli cells from Sertoli cell-enriched cultures. | 1989 | J. Reprod. Fertil. | pmid:2495356 |
| Pérez-Palacios T et al. | Influence of pre-cure freezing on the profile of volatile compounds during the processing of Iberian hams. | 2010 | J. Sci. Food Agric. | pmid:20355126 |
| Neef K et al. | Mechanical preconditioning enables electrophysiologic coupling of skeletal myoblast cells to myocardium. | 2012 | J. Thorac. Cardiovasc. Surg. | pmid:22980065 |
| Saltman AE et al. | Gap junction uncoupling protects the heart against ischemia. | 2002 | J. Thorac. Cardiovasc. Surg. | pmid:12167798 |
| Berra-Romani R et al. | The mechanism of injury-induced intracellular calcium concentration oscillations in the endothelium of excised rat aorta. | 2012 | J. Vasc. Res. | pmid:21997119 |
| Watts SW et al. | Gap junctional communication and vascular smooth muscle reactivity: use of tetraethylammonium chloride. | 1994 Nov-Dec | J. Vasc. Res. | pmid:7986954 |
| Javid PJ et al. | Inhibition of nitric oxide-induced vasodilation by gap junction inhibitors: a potential role for a cGMP-independent nitric oxide pathway. | 1996 Sep-Oct | J. Vasc. Res. | pmid:8862145 |
| Asari A et al. | Hyaluronan, CD44 and fibronectin in rabbit corneal epithelial wound healing. | 1996 | Jpn. J. Ophthalmol. | pmid:8739496 |
| Nakayama S and Torihashi S | Spontaneous rhythmicity in cultured cell clusters isolated from mouse small intestine. | 2002 | Jpn. J. Physiol. | pmid:12139780 |
| Ren Y et al. | Role of mesangial cells and gap junctions in tubuloglomerular feedback. | 2002 | Kidney Int. | pmid:12110013 |
| Ye JH et al. | Functional connectivity map of retinal ganglion cells for retinal prosthesis. | 2008 | Korean J. Physiol. Pharmacol. | pmid:19967072 |
| Ye N et al. | Assay for molecular transport across gap junction channels in one-dimensional cell arrays. | 2011 | Lab Chip | pmid:21293824 |
| Christ GJ et al. | Intercellular communication through gap junctions: a potential role in pharmacomechanical coupling and syncytial tissue contraction in vascular smooth muscle isolated from the human corpus cavernosum. | 1991 | Life Sci. | pmid:1943478 |
| Christ GJ | Modulation of alpha 1-adrenergic contractility in isolated vascular tissues by heptanol: a functional demonstration of the potential importance of intercellular communication to vascular response generation. | 1995 | Life Sci. | pmid:7885187 |
| Wang P et al. | [The effect of gap blocker 1-heptanol on function and morphology of guinea pig cochlea]. | 2005 | Lin Chuang Er Bi Yan Hou Ke Za Zhi | pmid:16320719 |
| Yang ZH et al. | Pollock oil supplementation modulates hyperlipidemia and ameliorates hepatic steatosis in mice fed a high-fat diet. | 2011 | Lipids Health Dis | pmid:22027268 |
| Beermann C et al. | Short term effects of dietary medium-chain fatty acids and n-3 long-chain polyunsaturated fatty acids on the fat metabolism of healthy volunteers. | 2003 | Lipids Health Dis | pmid:14622442 |
| Schiødt FV et al. | Temporal profile of total, bound, and free Gc-globulin after acetaminophen overdose. | 2001 | Liver Transpl. | pmid:11510020 |
| Caillaud A et al. | Update on methodologies available for ciguatoxin determination: perspectives to confront the onset of ciguatera fish poisoning in Europe. | 2010 | Mar Drugs | pmid:20631873 |
| Peng J et al. | Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: metabolism and bioactivities relevant to human health. | 2011 | Mar Drugs | pmid:22072997 |
| Rembold M and Wittbrodt J | In vivo time-lapse imaging in medaka--n-heptanol blocks contractile rhythmical movements. | 2004 | Mech. Dev. | pmid:15210200 |
| Churmantaeva SKh | [Metabolic disorders and their correction in petrochemical production workers exposed to heptyl]. | 2003 | Med Tr Prom Ekol | pmid:14593652 |
| Profumo E et al. | Biomarkers of subclinical atherosclerosis in patients with autoimmune disorders. | 2012 | Mediators Inflamm. | pmid:22529523 |
| Tse G et al. | Gap junction inhibition by heptanol increases ventricular arrhythmogenicity by reducing conduction velocity without affecting repolarization properties or myocardial refractoriness in Langendorff-perfused mouse hearts. | 2016 | Mol Med Rep | pmid:27633494 |
| Furger C et al. | Human granulosa cells in culture exhibit functional cyclic AMP-regulated gap junctions. | 1996 | Mol. Hum. Reprod. | pmid:9239665 |
| Wood SC et al. | Channel inhibition by alkanols occurs at a binding site on the nicotinic acetylcholine receptor. | 1995 | Mol. Pharmacol. | pmid:7530805 |
| Coskun S and Lin YC | Effects of transforming growth factors and activin-A on in vitro porcine oocyte maturation. | 1994 | Mol. Reprod. Dev. | pmid:8080644 |
| Talarico EF | Plasma membrane calcium-ATPase isoform four distribution changes during corneal epithelial wound healing. | 2010 | Mol. Vis. | pmid:21139678 |
| Crooke A et al. | Silencing of P2Y2 receptor delays Ap4A-corneal re-epithelialization process. | 2009 | Mol. Vis. | pmid:19521552 |
| Martin FC and Handforth A | Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor. | 2006 | Mov. Disord. | pmid:16773639 |
| Olajos EJ et al. | Mutagenicity of alkyl-(omega-hydroxyalkyl) nitrosamines related to dibutylnitrosamine. | 1978 | Mutat. Res. | pmid:342939 |
| Chen H et al. | Expressing exogenous functional odorant receptors in cultured olfactory sensory neurons. | 2008 | Neural Dev | pmid:18786248 |
| Margineanu DG and Klitgaard H | Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability? | 2001 | Neuropharmacology | pmid:11522329 |
| Omura M et al. | In situ Ca2+ imaging of odor responses in a coronal olfactory epithelium slice. | 2003 | Neuroreport | pmid:12821794 |
| Tarner IH et al. | Heptanol exerts epileptiform effects in identified neurons of the buccal ganglia of Helix pomatia. | 1999 | Neurosci. Lett. | pmid:10320017 |
| Hirasawa H et al. | Blocking AMPA receptor desensitization prolongs spontaneous EPSC decay times and depolarizes H1 horizontal cells in carp retinal slices. | 2001 | Neurosci. Res. | pmid:11448513 |
| Young JS et al. | The origin of the skewed amplitude distribution of spontaneous excitatory junction potentials in poorly coupled smooth muscle cells. | 2007 | Neuroscience | pmid:17208381 |
| Adams JB et al. | Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. | 2011 | Nutr Metab (Lond) | pmid:21651783 |
| Yap AU et al. | Influence of dietary solvents on strength of nanofill and ormocer composites. | 2005 Jan-Feb | Oper Dent | pmid:15765968 |
| Chung JH et al. | Effect of topical Na-hyaluronan on hemidesmosome formation in n-heptanol-induced corneal injury. | 1998 | Ophthalmic Res. | pmid:9523287 |