| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uremia | D014511 | 33 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Ketosis | D007662 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carbon Tetrachloride Poisoning | D002252 | 12 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
3-Methyl-2-oxobutanoic acid
3-Methyl-2-oxobutanoic acid is a lipid of Fatty Acyls (FA) class. 3-methyl-2-oxobutanoic acid is associated with abnormalities such as Maple Syrup Urine Disease and Kidney Failure, Chronic. The involved functions are known as Phosphorylation, Citric Acid Cycle, inhibitors, Process and Metabolic Control. 3-methyl-2-oxobutanoic acid often locates in Mitochondria, BL21, Cytoplasm, Ribosomes and Head. The associated genes with 3-Methyl-2-oxobutanoic acid are Genome, Homologous Gene, Operon, Alleles and Oxidoreductase Gene. The related lipids are dimyristoylphosphatidylglycerol, 9-oxononanoic acid, Valerates and alpha-ketocaproic acid.
Cross Reference
Introduction
To understand associated biological information of 3-Methyl-2-oxobutanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 3-Methyl-2-oxobutanoic acid?
3-Methyl-2-oxobutanoic acid is suspected in Maple Syrup Urine Disease, Kidney Failure, Chronic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 3-Methyl-2-oxobutanoic acid
PubChem Associated disorders and diseases
What pathways are associated with 3-Methyl-2-oxobutanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 3-Methyl-2-oxobutanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 3-Methyl-2-oxobutanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 3-Methyl-2-oxobutanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 3-Methyl-2-oxobutanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 3-Methyl-2-oxobutanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 3-Methyl-2-oxobutanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shestopalov AI and Kristal BS | Branched chain keto-acids exert biphasic effects on alpha-ketoglutarate-stimulated respiration in intact rat liver mitochondria. | Neurochem. Res. | pmid:17342410 | |
| Tarnopolsky M | Protein requirements for endurance athletes. | Nutrition | pmid:15212749 | |
| pmid: | ||||
| WRETLIND KA | Replacement of valine in the diet by alpha-ketoisovaleric acid. | 1952 | Acta Physiol. Scand. | pmid:13050479 |
| ADELBERG EA and UMBARGER HE | Isoleucine and valine metabolism in Escherichia coli. V. alpha-Ketoisovaleric acid accumulation. | 1953 | J. Biol. Chem. | pmid:13117924 |
| MAAS WK and VOGEL HJ | alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. | 1953 | J. Bacteriol. | pmid:13069392 |
| ALLISON MJ et al. | Metabolic function of branched-chain volatile fatty acids, growth factors for ruminococci. II. Biosynthesis of higher branched-chain fatty acids and aldehydes. | 1962 | J. Bacteriol. | pmid:13860622 |
| BANERJEE R and WURMSER R | [Oxidoreduction potentials of the alanine-ammonium pyruvate and valine-ammonium alpha-ketoisovalerate systems. New determination]. | 1962 | Biochim. Biophys. Acta | pmid:13864621 |
| Gallina DL et al. | Maintenance of nitrogen balance in a young woman by substitution of -ketoisovaleric acid for valine. | 1971 | J. Nutr. | pmid:5096137 |
| Rudman D | Capacity of human subjects to utilize keto analogues of valine and phenylalanine. | 1971 | J. Clin. Invest. | pmid:5101299 |