Zhang M et al. |
C metabolic flux profiling of Pichia pastoris grown in aerobic batch cultures on glucose revealed high relative anabolic use of TCA cycle and limited incorporation of provided precursors of branched-chain amino acids. |
2017 |
FEBS J. |
pmid:28731268
|
Fukai K et al. |
Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men. |
2016 |
PLoS ONE |
pmid:27741291
|
Heemskerk MM et al. |
Reanalysis of mGWAS results and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism. |
2016 |
Eur. J. Hum. Genet. |
pmid:26014429
|
Song Y et al. |
Biotechnological production of alpha-keto acids: Current status and perspectives. |
2016 |
Bioresour. Technol. |
pmid:27575335
|
Kim J et al. |
Calmodulin-mediated suppression of 2-ketoisovalerate reductase in Beauveria bassiana beauvericin biosynthetic pathway. |
2016 |
Environ. Microbiol. |
pmid:27449895
|
Shibata K et al. |
High-performance liquid chromatographic method for profiling 2-oxo acids in urine and its application in evaluating vitamin status in rats. |
2016 |
Biosci. Biotechnol. Biochem. |
pmid:26745680
|
Chen X et al. |
Production of C4 and C5 branched-chain alcohols by engineered Escherichia. coli. |
2015 |
J. Ind. Microbiol. Biotechnol. |
pmid:26350079
|
Lee DW et al. |
Increased valinomycin production in mutants of Streptomyces sp. M10 defective in bafilomycin biosynthesis and branched-chain α-keto acid dehydrogenase complex expression. |
2015 |
J. Ind. Microbiol. Biotechnol. |
pmid:26335568
|
Sommer B et al. |
Detailed structure-function correlations of Bacillus subtilis acetolactate synthase. |
2015 |
Chembiochem |
pmid:25393087
|
Lu J et al. |
Characterization and modification of enzymes in the 2-ketoisovalerate biosynthesis pathway of Ralstonia eutropha H16. |
2015 |
Appl. Microbiol. Biotechnol. |
pmid:25081555
|
Bückle-Vallant V et al. |
Metabolic engineering of Corynebacterium glutamicum for 2-ketoisocaproate production. |
2014 |
Appl. Microbiol. Biotechnol. |
pmid:24169948
|
Lang K et al. |
Metabolic engineering of Pseudomonas sp. strain VLB120 as platform biocatalyst for the production of isobutyric acid and other secondary metabolites. |
2014 |
Microb. Cell Fact. |
pmid:24397404
|
Panten U et al. |
Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation. |
2013 |
Metab. Clin. Exp. |
pmid:23790612
|
Buchholz J et al. |
Platform engineering of Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate. |
2013 |
Appl. Environ. Microbiol. |
pmid:23835179
|
Miyanoiri Y et al. |
Differential isotope-labeling for Leu and Val residues in a protein by E. coli cellular expression using stereo-specifically methyl labeled amino acids. |
2013 |
J. Biomol. NMR |
pmid:24057411
|
Boulangé CL et al. |
Early metabolic adaptation in C57BL/6 mice resistant to high fat diet induced weight gain involves an activation of mitochondrial oxidative pathways. |
2013 |
J. Proteome Res. |
pmid:23473242
|
Saylor PJ et al. |
Prospective study of changes in the metabolomic profiles of men during their first three months of androgen deprivation therapy for prostate cancer. |
2012 |
Clin. Cancer Res. |
pmid:22589396
|
Jia X et al. |
Engineering a metabolic pathway for isobutanol biosynthesis in Bacillus subtilis. |
2012 |
Appl. Biochem. Biotechnol. |
pmid:21537892
|
Gutsche KA et al. |
Production of volatile compounds by Lactobacillus sakei from branched chain α-keto acids. |
2012 |
Food Microbiol. |
pmid:22202876
|
Li S et al. |
Improved 2-methyl-1-propanol production in an engineered Bacillus subtilis by constructing inducible pathways. |
2012 |
Biotechnol. Lett. |
pmid:22941373
|
Huisman FH et al. |
Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding. |
2012 |
Biochemistry |
pmid:22352945
|
Beaudet AL |
Neuroscience. Preventable forms of autism? |
2012 |
Science |
pmid:23087240
|
Novarino G et al. |
Mutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsy. |
2012 |
Science |
pmid:22956686
|
Zhang T et al. |
Cloning and characterization of a novel 2-ketoisovalerate reductase from the beauvericin producer Fusarium proliferatum LF061. |
2012 |
BMC Biotechnol. |
pmid:22916830
|
Lamsen EN and Atsumi S |
Recent progress in synthetic biology for microbial production of C3-C10 alcohols. |
2012 |
Front Microbiol |
pmid:22701113
|
Ensminger AW et al. |
Experimental evolution of Legionella pneumophila in mouse macrophages leads to strains with altered determinants of environmental survival. |
2012 |
PLoS Pathog. |
pmid:22693450
|
Liu Z et al. |
Complete Genome of Ignavibacterium album, a Metabolically Versatile, Flagellated, Facultative Anaerobe from the Phylum Chlorobi. |
2012 |
Front Microbiol |
pmid:22661972
|
Zhou M et al. |
Tissue-specific and nutrient regulation of the branched-chain α-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). |
2012 |
J. Biol. Chem. |
pmid:22589535
|
Hu W et al. |
Selective editing of Val and Leu methyl groups in high molecular weight protein NMR. |
2012 |
J. Biomol. NMR |
pmid:22532128
|
Qu SQ et al. |
[Acute encephalopathy due to late-onset maple syrup urine disease in a school boy]. |
2012 |
Zhongguo Dang Dai Er Ke Za Zhi |
pmid:22433398
|
Chanumolu SK et al. |
UniDrug-target: a computational tool to identify unique drug targets in pathogenic bacteria. |
2012 |
PLoS ONE |
pmid:22431985
|
van Leeuwen BN et al. |
Fermentative production of isobutene. |
2012 |
Appl. Microbiol. Biotechnol. |
pmid:22234536
|
Friedrich T et al. |
Mutation of zebrafish dihydrolipoamide branched-chain transacylase E2 results in motor dysfunction and models maple syrup urine disease. |
2012 |
Dis Model Mech |
pmid:22046030
|
Xiong M et al. |
A bio-catalytic approach to aliphatic ketones. |
2012 |
Sci Rep |
pmid:22416247
|
Zhang D et al. |
A novel ion-pair RP-HPLC method for determination of five components in compound α-ketoacid tablets. |
2012 |
J Pharm Biomed Anal |
pmid:22510314
|
Wang YP et al. |
Two novel mutations in the BCKDHB gene (R170H, Q346R) cause the classic form of maple syrup urine disease (MSUD). |
2012 |
Gene |
pmid:22326532
|
Di Cagno R et al. |
Duodenal and faecal microbiota of celiac children: molecular, phenotype and metabolome characterization. |
2011 |
BMC Microbiol. |
pmid:21970810
|
Savrasova EA et al. |
Use of the valine biosynthetic pathway to convert glucose into isobutanol. |
2011 |
J. Ind. Microbiol. Biotechnol. |
pmid:21161324
|
Baez A et al. |
High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal. |
2011 |
Appl. Microbiol. Biotechnol. |
pmid:21547458
|
Li S et al. |
Engineering Bacillus subtilis for isobutanol production by heterologous Ehrlich pathway construction and the biosynthetic 2-ketoisovalerate precursor pathway overexpression. |
2011 |
Appl. Microbiol. Biotechnol. |
pmid:21533914
|
Gong L et al. |
Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles. |
2011 |
Toxicol. Sci. |
pmid:21561886
|
van den Akker CH et al. |
Amino acid metabolism in the human fetus at term: leucine, valine, and methionine kinetics. |
2011 |
Pediatr. Res. |
pmid:21857387
|
Adams SH |
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. |
2011 |
Adv Nutr |
pmid:22332087
|
Zhang W et al. |
The fur transcription regulator and fur-regulated genes in Clostridium botulinum A ATCC 3502. |
2011 |
J. Biomed. Biotechnol. |
pmid:22203788
|
Chung JH et al. |
Proteomic and biochemical analyses reveal the activation of unfolded protein response, ERK-1/2 and ribosomal protein S6 signaling in experimental autoimmune myocarditis rat model. |
2011 |
BMC Genomics |
pmid:22014063
|
Lowe CD et al. |
The transcriptome of the novel dinoflagellate Oxyrrhis marina (Alveolata: Dinophyceae): response to salinity examined by 454 sequencing. |
2011 |
BMC Genomics |
pmid:22014029
|
Diebold AR et al. |
Activation of α-keto acid-dependent dioxygenases: application of an {FeNO}7/{FeO2}8 methodology for characterizing the initial steps of O2 activation. |
2011 |
J. Am. Chem. Soc. |
pmid:21981763
|
Qi F et al. |
Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. |
2011 |
BMC Biochem. |
pmid:21943256
|
Li JV et al. |
Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. |
2011 |
Parasit Vectors |
pmid:21929782
|
Tang KH et al. |
Carbon metabolic pathways in phototrophic bacteria and their broader evolutionary implications. |
2011 |
Front Microbiol |
pmid:21866228
|
Beste DJ et al. |
¹³C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation. |
2011 |
PLoS Pathog. |
pmid:21814509
|
Francke C et al. |
Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior. |
2011 |
BMC Genomics |
pmid:21806785
|
Chen X et al. |
Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism. |
2011 |
Biotechnol Biofuels |
pmid:21798060
|
Viñuelas J et al. |
Multimodal dynamic response of the Buchnera aphidicola pLeu plasmid to variations in leucine demand of its host, the pea aphid Acyrthosiphon pisum. |
2011 |
Mol. Microbiol. |
pmid:21797941
|
Keller KL and Wall JD |
Genetics and molecular biology of the electron flow for sulfate respiration in desulfovibrio. |
2011 |
Front Microbiol |
pmid:21747813
|
Tang X et al. |
Systems biology of the qa gene cluster in Neurospora crassa. |
2011 |
PLoS ONE |
pmid:21695121
|
Emes RD and Grant SG |
The human postsynaptic density shares conserved elements with proteomes of unicellular eukaryotes and prokaryotes. |
2011 |
Front Neurosci |
pmid:21503141
|
Villaseñor T et al. |
Housekeeping genes essential for pantothenate biosynthesis are plasmid-encoded in Rhizobium etli and Rhizobium leguminosarum. |
2011 |
BMC Microbiol. |
pmid:21463532
|
de Graaf RM et al. |
The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. |
2011 |
Mol. Biol. Evol. |
pmid:21378103
|
Hirani TA et al. |
Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. |
2011 |
Enzyme Res |
pmid:21318135
|
Li JV et al. |
Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections. |
2011 |
Am. J. Trop. Med. Hyg. |
pmid:21212208
|
de Kraker JW and Gershenzon J |
From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis. |
2011 |
Plant Cell |
pmid:21205930
|
Brunetti-Pierri N et al. |
Phenylbutyrate therapy for maple syrup urine disease. |
2011 |
Hum. Mol. Genet. |
pmid:21098507
|
Kaster AK et al. |
More than 200 genes required for methane formation from Hâ‚‚ and COâ‚‚ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. |
2011 |
Archaea |
pmid:21559116
|
Park HD et al. |
Three Korean patients with maple syrup urine disease: four novel mutations in the BCKDHA gene. |
2011 |
Ann. Clin. Lab. Sci. |
pmid:21844576
|
Mescka C et al. |
In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease. |
2011 |
Metab Brain Dis |
pmid:21380499
|
Sakuragi H et al. |
Molecular breeding of advanced microorganisms for biofuel production. |
2011 |
J. Biomed. Biotechnol. |
pmid:21318120
|
Gall WE et al. |
alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population. |
2010 |
PLoS ONE |
pmid:20526369
|
Atsumi S et al. |
Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19609521
|
Smith KM et al. |
Engineering Corynebacterium glutamicum for isobutanol production. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:20376637
|
Connor SC et al. |
Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. |
2010 |
Mol Biosyst |
pmid:20567778
|
Krause FS et al. |
Metabolic engineering of Corynebacterium glutamicum for 2-ketoisovalerate production. |
2010 |
Appl. Environ. Microbiol. |
pmid:20935122
|
Spring S et al. |
Complete genome sequence of Thermosphaera aggregans type strain (M11TL). |
2010 |
Stand Genomic Sci |
pmid:21304709
|
Espinoza C et al. |
Interaction with diurnal and circadian regulation results in dynamic metabolic and transcriptional changes during cold acclimation in Arabidopsis. |
2010 |
PLoS ONE |
pmid:21124901
|
McKinlay JB et al. |
A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. |
2010 |
BMC Genomics |
pmid:21118570
|
Iwasaki T |
Iron-sulfur world in aerobic and hyperthermoacidophilic archaea Sulfolobus. |
2010 |
Archaea |
pmid:20885930
|
Cottret L et al. |
Graph-based analysis of the metabolic exchanges between two co-resident intracellular symbionts, Baumannia cicadellinicola and Sulcia muelleri, with their insect host, Homalodisca coagulata. |
2010 |
PLoS Comput. Biol. |
pmid:20838465
|
Connor MR and Atsumi S |
Synthetic biology guides biofuel production. |
2010 |
J. Biomed. Biotechnol. |
pmid:20827393
|
Wu J et al. |
Metabolic changes reveal the development of schistosomiasis in mice. |
2010 |
PLoS Negl Trop Dis |
pmid:20824219
|
Larson EM and Idnurm A |
Two origins for the gene encoding alpha-isopropylmalate synthase in fungi. |
2010 |
PLoS ONE |
pmid:20657649
|
Hao T et al. |
Compartmentalization of the Edinburgh Human Metabolic Network. |
2010 |
BMC Bioinformatics |
pmid:20649990
|
Petit-Haertlein I et al. |
Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies. |
2010 |
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. |
pmid:20516595
|
Cann AF and Liao JC |
Pentanol isomer synthesis in engineered microorganisms. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19859707
|
Maloney GS et al. |
Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato. |
2010 |
Plant Physiol. |
pmid:20435740
|
Dobritsa AA et al. |
LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. |
2010 |
Plant Physiol. |
pmid:20442277
|
|
Genome sequence of the pea aphid Acyrthosiphon pisum. |
2010 |
PLoS Biol. |
pmid:20186266
|
Carleton SM et al. |
DNA carrier testing and newborn screening for maple syrup urine disease in Old Order Mennonite communities. |
2010 |
Genet Test Mol Biomarkers |
pmid:20136525
|
Widmann M et al. |
The Thiamine diphosphate dependent Enzyme Engineering Database: a tool for the systematic analysis of sequence and structure relations. |
2010 |
BMC Biochem. |
pmid:20122171
|
Pei XY et al. |
Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis . |
2010 |
Biochemistry |
pmid:20099870
|
Saric J et al. |
Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents. |
2010 |
J. Proteome Res. |
pmid:20092362
|
Dellomonaco C et al. |
The path to next generation biofuels: successes and challenges in the era of synthetic biology. |
2010 |
Microb. Cell Fact. |
pmid:20089184
|
Barve A et al. |
A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli. |
2010 |
Adv Appl Bioinform Chem |
pmid:21918631
|
Schilmiller A et al. |
Mass spectrometry screening reveals widespread diversity in trichome specialized metabolites of tomato chromosomal substitution lines. |
2010 |
Plant J. |
pmid:20113441
|
Ranganathan S and Maranas CD |
Microbial 1-butanol production: Identification of non-native production routes and in silico engineering interventions. |
2010 |
Biotechnol J |
pmid:20665644
|
De Souza AI et al. |
Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure. |
2010 |
J. Mol. Cell. Cardiol. |
pmid:20655923
|
Wiltafsky MK et al. |
The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs. |
2010 |
Br. J. Nutr. |
pmid:20196890
|
Huisman FH et al. |
The C-terminal regulatory domain is required for catalysis by Neisseria meningitidis alpha-isopropylmalate synthase. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20117081
|
Matsumoto H et al. |
Analysis of branched-chain alpha-keto acid dehydrogenase complex activity in rat tissues using alpha-keto[1-13C]isocaproate as substrate. |
2010 |
Anal. Biochem. |
pmid:20018161
|
Wang YH et al. |
Regulation of branched-chain amino acid catabolism: glucose limitation enhances the component of isovalerylspiramycin for the bitespiramycin production. |
2010 |
Bioprocess Biosyst Eng |
pmid:19415340
|
Graca G et al. |
Impact of prenatal disorders on the metabolic profile of second trimester amniotic fluid: a nuclear magnetic resonance metabonomic study. |
2010 |
J. Proteome Res. |
pmid:20849080
|