| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
Total
2
1250-95-9
1250-95-9 is a lipid of Sterol Lipids (ST) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 303 references associated with 1250-95-9 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
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All references with 1250-95-9
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Ahn DU et al. | Analysis of cholesterol oxides in egg yolk and turkey meat. | 1999 | Poult. Sci. | pmid:10404689 |
| Zhou Q et al. | An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells. | 2000 | Atherosclerosis | pmid:10704631 |
| O'Callaghan YC et al. | Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols. | 2001 | Cell Biol. Toxicol. | pmid:11499696 |
| Staprans I et al. | Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. | 2003 | J. Lipid Res. | pmid:12562864 |
| O'Sullivan AJ et al. | Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol. | 2003 May-Jun | J Appl Toxicol | pmid:12794941 |
| Pulfer MK and Murphy RC | Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant. | 2004 | J. Biol. Chem. | pmid:15096493 |
| Ryan L et al. | Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. | 2004 | Cell Biol. Toxicol. | pmid:15685934 |
| Cheng YW et al. | Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation. | 2005 | Food Chem. Toxicol. | pmid:15721210 |
| Anspaugh DD and Roe RM | Regulation of JH epoxide hydrolase versus JH esterase activity in the cabbage looper, Trichoplusia ni, by juvenile hormone and xenobiotics. | 2005 | J. Insect Physiol. | pmid:15893999 |
| Johansson P et al. | Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function. | 2005 | J. Mol. Biol. | pmid:16051262 |
| Ryan L et al. | The role of the mitochondria in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. | 2005 | Br. J. Nutr. | pmid:16197575 |
| Ryan L et al. | Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis. | 2006 Jan-Feb | Int. J. Toxicol. | pmid:16510355 |
| Ferderbar S et al. | Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. | 2007 | Diabetes Metab. Res. Rev. | pmid:16634125 |
| Lordan S et al. | Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. | 2007 | J. Biochem. Mol. Toxicol. | pmid:17994574 |
| Lordan S et al. | Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis. | 2008 | Int. J. Toxicol. | pmid:18569169 |
| Arshad MA et al. | Plasma lipoprotein peroxidation potential: a test to evaluate individual susceptibility to peroxidation. | 1991 | Clin. Chem. | pmid:1914180 |
| Sevanian A et al. | Uptake, metabolism, and cytotoxicity of isomeric cholesterol-5,6-epoxides in rabbit aortic endothelial cells. | 1991 | J. Lipid Res. | pmid:2010686 |
| Ma MT et al. | Effects of cholesterol oxidation products on exocytosis. | 2010 | Neurosci. Lett. | pmid:20380872 |
| Moody DE et al. | Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes. | 1991 | Biochem. Pharmacol. | pmid:2043152 |
| Liao PL et al. | 7-Ketocholesterol and cholesterol-5alpha,6alpha-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways. | 2010 | Toxicol. Lett. | pmid:20466046 |
| Morin RJ et al. | Cholesterol oxides and carcinogenesis. | 1991 | J. Clin. Lab. Anal. | pmid:2061746 |
| Paillasse MR et al. | Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles. | 2012 | J. Lipid Res. | pmid:22285872 |
| Ansari GA and Smith LL | Cholesterol epoxides: formation and measurement. | 1990 | Meth. Enzymol. | pmid:2233310 |
| Poirot M and Silvente-Poirot S | Cholesterol-5,6-epoxides: chemistry, biochemistry, metabolic fate and cancer. | 2013 | Biochimie | pmid:22613256 |
| Morisseau C | Role of epoxide hydrolases in lipid metabolism. | 2013 | Biochimie | pmid:22722082 |
| Silvente-Poirot S and Poirot M | Cholesterol epoxide hydrolase and cancer. | 2012 | Curr Opin Pharmacol | pmid:22917620 |
| Jové M et al. | Human omental and subcutaneous adipose tissue exhibit specific lipidomic signatures. | 2014 | FASEB J. | pmid:24265485 |
| Windsor K et al. | Assay of protein and peptide adducts of cholesterol ozonolysis products by hydrophobic and click enrichment methods. | 2014 | Chem. Res. Toxicol. | pmid:25185119 |
| Wrensch MR et al. | Breast fluid cholesterol and cholesterol beta-epoxide concentrations in women with benign breast disease. | 1989 | Cancer Res. | pmid:2702658 |
| Musman J et al. | Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice. | 2016 | Free Radic. Biol. Med. | pmid:27989751 |
| Chang CC et al. | Effect of cholesterol epoxides on the inhibition of intercellular communication and on mutation induction in Chinese hamster V79 cells. | 1988 | Mutat. Res. | pmid:2849716 |
| Jacobson MS | Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations. | 1987 | Lancet | pmid:2887943 |
| Voisin M et al. | Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29078321 |
| Peterson AR et al. | Mutagenic characterization of cholesterol epoxides in Chinese hamster V79 cells. | 1988 | Mutat. Res. | pmid:3173386 |
| Björkhem I et al. | Assay of unesterified cholesterol-5,6-epoxide in human serum by isotope dilution mass spectrometry. Levels in the healthy state and in hyperlipoproteinemia. | 1988 | J. Lipid Res. | pmid:3183516 |
| Maerker G et al. | Reaction of cholesterol 5,6-epoxides with simulated gastric juice. | 1988 | Lipids | pmid:3185108 |
| Raaphorst GP et al. | Effect of cholesterol alpha and beta epoxides on cell killing and transformation. | 1987 | Biochem. Pharmacol. | pmid:3606646 |
| Gruenke LD et al. | Breast fluid cholesterol and cholesterol epoxides: relationship to breast cancer risk factors and other characteristics. | 1987 | Cancer Res. | pmid:3652048 |
| Higley NA et al. | Comparative atherogenic effects of cholesterol and cholesterol oxides. | 1986 | Atherosclerosis | pmid:3801085 |
| Bascoul J et al. | Intestinal absorption and fecal excretion of 5,6 alpha-epoxy-5 alpha-cholesta-3 beta-ol by the male Wistar rat. | 1986 | Lipids | pmid:3821388 |
| Sevanian A and McLeod LL | Catalytic properties and inhibition of hepatic cholesterol-epoxide hydrolase. | 1986 | J. Biol. Chem. | pmid:3941086 |
| Sporer A et al. | Epoxycholesterols in secretions and tissues of normal, benign, and cancerous human prostate glands. | 1982 | Urology | pmid:6181602 |
| Levin W et al. | Distinct rat hepatic microsomal epoxide hydrolases catalyze the hydration of cholesterol 5,6 alpha-oxide and certain xenobiotic alkene and arene oxides. | 1983 | Arch. Biochem. Biophys. | pmid:6401984 |
| Watabe T et al. | A mechanism for epoxidation of cholesterol by hepatic microsomal lipid hydroperoxides. | 1984 | Biochim. Biophys. Acta | pmid:6466699 |
| Sevanian A and Peterson AR | Cholesterol epoxide is a direct-acting mutagen. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6588383 |
| Baranowski A et al. | Connective tissue responses to oxysterols. | 1982 | Atherosclerosis | pmid:7066074 |
| Watabe T et al. | Epoxidation of cholesterol by hepatic microsomal lipid hydroperoxides. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7150318 |
| Meyer DJ and Ketterer B | 5 alpha,6 alpha-Epoxy-cholestan-3 beta-ol (cholesterol alpha-oxide): A specific substrate for rat liver glutathione transferase B. | 1982 | FEBS Lett. | pmid:7160489 |
| Petrakis NL et al. | Cholesterol and cholesterol epoxides in nipple aspirates of human breast fluid. | 1981 | Cancer Res. | pmid:7237447 |