1250-95-9

1250-95-9 is a lipid of Sterol Lipids (ST) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 303 references associated with 1250-95-9 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 1250-95-9

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1250-95-9

MeSH term MeSH ID Detail
Hyperlipoproteinemia Type III D006952 4 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Total 2

NCBI Entrez Crosslinks

All references with 1250-95-9

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Authors Title Published Journal PubMed Link
Moody DE et al. Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes. 1991 Biochem. Pharmacol. pmid:2043152
Ma MT et al. Effects of cholesterol oxidation products on exocytosis. 2010 Neurosci. Lett. pmid:20380872
Sevanian A et al. Uptake, metabolism, and cytotoxicity of isomeric cholesterol-5,6-epoxides in rabbit aortic endothelial cells. 1991 J. Lipid Res. pmid:2010686
Arshad MA et al. Plasma lipoprotein peroxidation potential: a test to evaluate individual susceptibility to peroxidation. 1991 Clin. Chem. pmid:1914180
Lordan S et al. Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis. 2008 Int. J. Toxicol. pmid:18569169
Lordan S et al. Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. 2007 J. Biochem. Mol. Toxicol. pmid:17994574
Ferderbar S et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. 2007 Diabetes Metab. Res. Rev. pmid:16634125
Ryan L et al. Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis. 2006 Jan-Feb Int. J. Toxicol. pmid:16510355
Ryan L et al. The role of the mitochondria in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. 2005 Br. J. Nutr. pmid:16197575
Johansson P et al. Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function. 2005 J. Mol. Biol. pmid:16051262
Anspaugh DD and Roe RM Regulation of JH epoxide hydrolase versus JH esterase activity in the cabbage looper, Trichoplusia ni, by juvenile hormone and xenobiotics. 2005 J. Insect Physiol. pmid:15893999
Cheng YW et al. Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation. 2005 Food Chem. Toxicol. pmid:15721210
Ryan L et al. Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. 2004 Cell Biol. Toxicol. pmid:15685934
Pulfer MK and Murphy RC Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant. 2004 J. Biol. Chem. pmid:15096493
O'Sullivan AJ et al. Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol. 2003 May-Jun J Appl Toxicol pmid:12794941
Staprans I et al. Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. 2003 J. Lipid Res. pmid:12562864
O'Callaghan YC et al. Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols. 2001 Cell Biol. Toxicol. pmid:11499696
Zhou Q et al. An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells. 2000 Atherosclerosis pmid:10704631
Ahn DU et al. Analysis of cholesterol oxides in egg yolk and turkey meat. 1999 Poult. Sci. pmid:10404689
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