1250-95-9

1250-95-9 is a lipid of Sterol Lipids (ST) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 303 references associated with 1250-95-9 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 1250-95-9

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1250-95-9

MeSH term MeSH ID Detail
Hyperlipoproteinemia Type III D006952 4 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Total 2

NCBI Entrez Crosslinks

All references with 1250-95-9

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Authors Title Published Journal PubMed Link
Sporer A et al. Epoxycholesterols in secretions and tissues of normal, benign, and cancerous human prostate glands. 1982 Urology pmid:6181602
Liao PL et al. 7-Ketocholesterol and cholesterol-5alpha,6alpha-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways. 2010 Toxicol. Lett. pmid:20466046
Sevanian A and Peterson AR Cholesterol epoxide is a direct-acting mutagen. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6588383
Voisin M et al. Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29078321
Ahn DU et al. Analysis of cholesterol oxides in egg yolk and turkey meat. 1999 Poult. Sci. pmid:10404689
Ma MT et al. Effects of cholesterol oxidation products on exocytosis. 2010 Neurosci. Lett. pmid:20380872
Chang CC et al. Effect of cholesterol epoxides on the inhibition of intercellular communication and on mutation induction in Chinese hamster V79 cells. 1988 Mutat. Res. pmid:2849716
Peterson AR et al. Mutagenic characterization of cholesterol epoxides in Chinese hamster V79 cells. 1988 Mutat. Res. pmid:3173386
Ansari GA and Smith LL Cholesterol epoxides: formation and measurement. 1990 Meth. Enzymol. pmid:2233310
Bascoul J et al. Intestinal absorption and fecal excretion of 5,6 alpha-epoxy-5 alpha-cholesta-3 beta-ol by the male Wistar rat. 1986 Lipids pmid:3821388
Maerker G et al. Reaction of cholesterol 5,6-epoxides with simulated gastric juice. 1988 Lipids pmid:3185108
Black HS Analysis and physiologic significance of cholesterol epoxide in animal tissues. 1980 Lipids pmid:7421427
Jacobson MS Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations. 1987 Lancet pmid:2887943
Johansson P et al. Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function. 2005 J. Mol. Biol. pmid:16051262
Björkhem I et al. Assay of unesterified cholesterol-5,6-epoxide in human serum by isotope dilution mass spectrometry. Levels in the healthy state and in hyperlipoproteinemia. 1988 J. Lipid Res. pmid:3183516
Paillasse MR et al. Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles. 2012 J. Lipid Res. pmid:22285872
van den Berg JJ et al. Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry. 1993 J. Lipid Res. pmid:8263423
Sevanian A et al. Uptake, metabolism, and cytotoxicity of isomeric cholesterol-5,6-epoxides in rabbit aortic endothelial cells. 1991 J. Lipid Res. pmid:2010686
Staprans I et al. Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum. 2003 J. Lipid Res. pmid:12562864
Anspaugh DD and Roe RM Regulation of JH epoxide hydrolase versus JH esterase activity in the cabbage looper, Trichoplusia ni, by juvenile hormone and xenobiotics. 2005 J. Insect Physiol. pmid:15893999