1250-95-9

1250-95-9 is a lipid of Sterol Lipids (ST) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 303 references associated with 1250-95-9 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 1250-95-9

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1250-95-9

MeSH term MeSH ID Detail
Hyperlipoproteinemia Type III D006952 4 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Total 2

NCBI Entrez Crosslinks

All references with 1250-95-9

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Authors Title Published Journal PubMed Link
Wrensch MR et al. Breast fluid cholesterol and cholesterol beta-epoxide concentrations in women with benign breast disease. 1989 Cancer Res. pmid:2702658
O'Callaghan YC et al. Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols. 2001 Cell Biol. Toxicol. pmid:11499696
Ryan L et al. Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. 2004 Cell Biol. Toxicol. pmid:15685934
Windsor K et al. Assay of protein and peptide adducts of cholesterol ozonolysis products by hydrophobic and click enrichment methods. 2014 Chem. Res. Toxicol. pmid:25185119
Arshad MA et al. Plasma lipoprotein peroxidation potential: a test to evaluate individual susceptibility to peroxidation. 1991 Clin. Chem. pmid:1914180
Silvente-Poirot S and Poirot M Cholesterol epoxide hydrolase and cancer. 2012 Curr Opin Pharmacol pmid:22917620
Ferderbar S et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. 2007 Diabetes Metab. Res. Rev. pmid:16634125
Müller F et al. Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates. 1997 Eur. J. Biochem. pmid:9151984
Jové M et al. Human omental and subcutaneous adipose tissue exhibit specific lipidomic signatures. 2014 FASEB J. pmid:24265485
Meyer DJ and Ketterer B 5 alpha,6 alpha-Epoxy-cholestan-3 beta-ol (cholesterol alpha-oxide): A specific substrate for rat liver glutathione transferase B. 1982 FEBS Lett. pmid:7160489
Cheng YW et al. Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation. 2005 Food Chem. Toxicol. pmid:15721210
Sevanian A et al. Analysis of plasma cholesterol oxidation products using gas- and high-performance liquid chromatography/mass spectrometry. 1994 Free Radic. Biol. Med. pmid:7835746
Musman J et al. Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice. 2016 Free Radic. Biol. Med. pmid:27989751
Ryan L et al. Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis. 2006 Jan-Feb Int. J. Toxicol. pmid:16510355
Lordan S et al. Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis. 2008 Int. J. Toxicol. pmid:18569169
O'Sullivan AJ et al. Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol. 2003 May-Jun J Appl Toxicol pmid:12794941
Lordan S et al. Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. 2007 J. Biochem. Mol. Toxicol. pmid:17994574
Sevanian A and McLeod LL Catalytic properties and inhibition of hepatic cholesterol-epoxide hydrolase. 1986 J. Biol. Chem. pmid:3941086
Pulfer MK and Murphy RC Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant. 2004 J. Biol. Chem. pmid:15096493
Morin RJ et al. Cholesterol oxides and carcinogenesis. 1991 J. Clin. Lab. Anal. pmid:2061746