|
|
|
|
pmid:
|
Nelson JA et al. |
Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide. |
1981 |
J. Biol. Chem. |
pmid:7451488
|
Saucier SE et al. |
Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts. |
1985 |
J. Biol. Chem. |
pmid:4055791
|
Spencer TA et al. |
24(S),25-Epoxycholesterol. Evidence consistent with a role in the regulation of hepatic cholesterogenesis. |
1985 |
J. Biol. Chem. |
pmid:4055739
|
Taylor FR et al. |
24,25-Epoxysterol metabolism in cultured mammalian cells and repression of 3-hydroxy-3-methylglutaryl-CoA reductase. |
1986 |
J. Biol. Chem. |
pmid:3771561
|
Gupta A et al. |
Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestinal epithelial cells. |
1986 |
J. Biol. Chem. |
pmid:3722155
|
Panini SR et al. |
Regulation of sterol biosynthesis and of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in cultured cells by progesterone. |
1987 |
J. Biol. Chem. |
pmid:3667583
|
Emmons GT et al. |
24,25-epoxysterols. Differentiation of 24R and 24S epimers by 13C nuclear magnetic resonance spectroscopy. |
1989 |
J. Lipid Res. |
pmid:2918248
|
Panini SR et al. |
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol. |
1992 |
J. Biol. Chem. |
pmid:1618770
|
Saucier SE et al. |
Hepatic uptake and metabolism of ingested 24-hydroxycholesterol and 24(S),25-epoxycholesterol. |
1993 |
Biochim. Biophys. Acta |
pmid:8431485
|
Dollis D and Schuber F |
Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2. |
1994 |
Biochem. Pharmacol. |
pmid:8043030
|
Lehmann JM et al. |
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. |
1997 |
J. Biol. Chem. |
pmid:9013544
|
Janowski BA et al. |
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9874807
|
Li D and Spencer TA |
Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. |
2000 |
Steroids |
pmid:10978732
|
Ou J et al. |
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11371634
|
Spencer TA et al. |
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. |
2001 |
J. Med. Chem. |
pmid:11300870
|
Zhang Z et al. |
Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. |
2001 |
J. Lipid Res. |
pmid:11290837
|
Kömüves LG et al. |
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. |
2002 |
J. Invest. Dermatol. |
pmid:11851872
|
Rowe AH et al. |
Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation. |
2003 |
Circ. Res. |
pmid:14512442
|
Kaneko E et al. |
Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. |
2003 |
J. Biol. Chem. |
pmid:12847102
|