24(S),25-Epoxycholesterol

24(S),25-Epoxycholesterol is a lipid of Sterol Lipids (ST) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 285 references associated with 24(S),25-Epoxycholesterol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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All references with 24(S),25-Epoxycholesterol

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Zeng J et al. Liver X receptors agonists impede hepatitis C virus infection in an Idol-dependent manner. 2012 Antiviral Res. pmid:22713431
Wang Z et al. Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury. 2017 Arch. Toxicol. pmid:27052460
Wong J et al. Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux. 2004 Arterioscler. Thromb. Vasc. Biol. pmid:15514210
Heverin M et al. Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol. 2007 Arterioscler. Thromb. Vasc. Biol. pmid:17761942
Ouimet M et al. Epoxycholesterol impairs cholesteryl ester hydrolysis in macrophage foam cells, resulting in decreased cholesterol efflux. 2008 Arterioscler. Thromb. Vasc. Biol. pmid:18369155
Bjorkhem I and Diczfalusy U 24(S),25-epoxycholesterol--a potential friend. 2004 Arterioscler. Thromb. Vasc. Biol. pmid:15576644
Morello F et al. LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms. 2009 Atherosclerosis pmid:19426978
Wang Y et al. 24S,25-Epoxycholesterol in mouse and rat brain. 2014 Biochem. Biophys. Res. Commun. pmid:24832732
Meljon A et al. Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse. 2014 Biochem. Biophys. Res. Commun. pmid:24491562
Wong J et al. SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR. 2006 Biochem. J. pmid:16901265
Duniec-Dmuchowski Z et al. Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists. 2007 Biochem. Pharmacol. pmid:17825266
Dollis D and Schuber F Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2. 1994 Biochem. Pharmacol. pmid:8043030
Mazein A et al. A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway. 2013 Biochem. Pharmacol. pmid:23583456
Bentinger M et al. Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis. 2014 Biochim. Biophys. Acta pmid:24747199
Zerenturk EJ et al. The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1). 2012 Biochim. Biophys. Acta pmid:22178193
Saucier SE et al. Hepatic uptake and metabolism of ingested 24-hydroxycholesterol and 24(S),25-epoxycholesterol. 1993 Biochim. Biophys. Acta pmid:8431485
Ando H et al. Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro. 2010 Biochim. Biophys. Acta pmid:20045741
Swahn BM et al. Liver X receptor agonists with selectivity for LXRbeta; N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides. 2009 Bioorg. Med. Chem. Lett. pmid:19264481
Li L et al. Discovery and optimization of a novel series of liver X receptor-alpha agonists. 2006 Bioorg. Med. Chem. Lett. pmid:16386417