Li D and Spencer TA |
Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. |
2000 |
Steroids |
pmid:10978732
|
Janowski BA et al. |
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9874807
|
Ou J et al. |
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11371634
|
Hong YF et al. |
Lactobacillus acidophilus K301 Inhibits Atherogenesis via Induction of 24 (S), 25-Epoxycholesterol-Mediated ABCA1 and ABCG1 Production and Cholesterol Efflux in Macrophages. |
2016 |
PLoS ONE |
pmid:27120199
|
Theofilopoulos S et al. |
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. |
2013 |
Nat. Chem. Biol. |
pmid:23292650
|
Trasino SE et al. |
Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells. |
2009 |
Mol. Cancer Ther. |
pmid:19531574
|
Brown AJ and Jessup W |
Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. |
2009 |
Mol. Aspects Med. |
pmid:19248801
|
Endo-Umeda K et al. |
1α-Hydroxy derivatives of 7-dehydrocholesterol are selective liver X receptor modulators. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:28736297
|
Reschly EJ et al. |
Ligand specificity and evolution of liver X receptors. |
2008 |
J. Steroid Biochem. Mol. Biol. |
pmid:18395439
|
Wong J et al. |
Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. |
2007 |
J. Neurochem. |
pmid:17956548
|
Spencer TA et al. |
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. |
2001 |
J. Med. Chem. |
pmid:11300870
|
Cheng JF et al. |
Combination of virtual screening and high throughput gene profiling for identification of novel liver X receptor modulators. |
2008 |
J. Med. Chem. |
pmid:18324758
|
Emmons GT et al. |
24,25-epoxysterols. Differentiation of 24R and 24S epimers by 13C nuclear magnetic resonance spectroscopy. |
1989 |
J. Lipid Res. |
pmid:2918248
|
Zhang Z et al. |
Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. |
2001 |
J. Lipid Res. |
pmid:11290837
|
Kömüves LG et al. |
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. |
2002 |
J. Invest. Dermatol. |
pmid:11851872
|
Zapata-Gonzalez F et al. |
9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. |
2007 |
J. Immunol. |
pmid:17475839
|
Davies JD et al. |
Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells. |
2005 |
J. Biol. Chem. |
pmid:15548517
|
Williams S et al. |
X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch. |
2003 |
J. Biol. Chem. |
pmid:12736258
|
Kaneko E et al. |
Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. |
2003 |
J. Biol. Chem. |
pmid:12847102
|
Panini SR et al. |
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol. |
1992 |
J. Biol. Chem. |
pmid:1618770
|