24(S),25-Epoxycholesterol

24(S),25-Epoxycholesterol is a lipid of Sterol Lipids (ST) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 285 references associated with 24(S),25-Epoxycholesterol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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All references with 24(S),25-Epoxycholesterol

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Authors Title Published Journal PubMed Link
Li D and Spencer TA Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. 2000 Steroids pmid:10978732
Janowski BA et al. Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874807
Ou J et al. Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11371634
Hong YF et al. Lactobacillus acidophilus K301 Inhibits Atherogenesis via Induction of 24 (S), 25-Epoxycholesterol-Mediated ABCA1 and ABCG1 Production and Cholesterol Efflux in Macrophages. 2016 PLoS ONE pmid:27120199
Theofilopoulos S et al. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. 2013 Nat. Chem. Biol. pmid:23292650
Trasino SE et al. Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells. 2009 Mol. Cancer Ther. pmid:19531574
Brown AJ and Jessup W Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. 2009 Mol. Aspects Med. pmid:19248801
Endo-Umeda K et al. 1α-Hydroxy derivatives of 7-dehydrocholesterol are selective liver X receptor modulators. 2017 J. Steroid Biochem. Mol. Biol. pmid:28736297
Reschly EJ et al. Ligand specificity and evolution of liver X receptors. 2008 J. Steroid Biochem. Mol. Biol. pmid:18395439
Wong J et al. Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. 2007 J. Neurochem. pmid:17956548
Spencer TA et al. Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. 2001 J. Med. Chem. pmid:11300870
Cheng JF et al. Combination of virtual screening and high throughput gene profiling for identification of novel liver X receptor modulators. 2008 J. Med. Chem. pmid:18324758
Emmons GT et al. 24,25-epoxysterols. Differentiation of 24R and 24S epimers by 13C nuclear magnetic resonance spectroscopy. 1989 J. Lipid Res. pmid:2918248
Zhang Z et al. Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. 2001 J. Lipid Res. pmid:11290837
Kömüves LG et al. Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. 2002 J. Invest. Dermatol. pmid:11851872
Zapata-Gonzalez F et al. 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. 2007 J. Immunol. pmid:17475839
Davies JD et al. Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells. 2005 J. Biol. Chem. pmid:15548517
Williams S et al. X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch. 2003 J. Biol. Chem. pmid:12736258
Kaneko E et al. Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. 2003 J. Biol. Chem. pmid:12847102
Panini SR et al. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol. 1992 J. Biol. Chem. pmid:1618770