| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Li D and Spencer TA | Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. | 2000 | Steroids | pmid:10978732 |
| Zhang Z et al. | Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. | 2001 | J. Lipid Res. | pmid:11290837 |
| Spencer TA et al. | Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. | 2001 | J. Med. Chem. | pmid:11300870 |
| Ou J et al. | Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11371634 |
| Kömüves LG et al. | Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. | 2002 | J. Invest. Dermatol. | pmid:11851872 |
| Williams S et al. | X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch. | 2003 | J. Biol. Chem. | pmid:12736258 |
| Kaneko E et al. | Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. | 2003 | J. Biol. Chem. | pmid:12847102 |
| Rowe AH et al. | Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation. | 2003 | Circ. Res. | pmid:14512442 |
| Wong J et al. | Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:15514210 |
| Davies JD et al. | Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells. | 2005 | J. Biol. Chem. | pmid:15548517 |
| Bjorkhem I and Diczfalusy U | 24(S),25-epoxycholesterol--a potential friend. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:15576644 |
| Panini SR et al. | Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol. | 1992 | J. Biol. Chem. | pmid:1618770 |
| Li L et al. | Discovery and optimization of a novel series of liver X receptor-alpha agonists. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16386417 |
| Wong J et al. | SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR. | 2006 | Biochem. J. | pmid:16901265 |
| Beyea MM et al. | Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. | 2007 | J. Biol. Chem. | pmid:17186944 |
| Zapata-Gonzalez F et al. | 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. | 2007 | J. Immunol. | pmid:17475839 |
| Heverin M et al. | Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17761942 |
| Duniec-Dmuchowski Z et al. | Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists. | 2007 | Biochem. Pharmacol. | pmid:17825266 |
| Wong J et al. | Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. | 2007 | J. Neurochem. | pmid:17956548 |
24(S),25-Epoxycholesterol
24(S),25-Epoxycholesterol is a lipid of Sterol Lipids (ST) class.
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