24(S),25-Epoxycholesterol

24(S),25-Epoxycholesterol is a lipid of Sterol Lipids (ST) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 285 references associated with 24(S),25-Epoxycholesterol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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All references with 24(S),25-Epoxycholesterol

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Authors Title Published Journal PubMed Link
Moya M et al. Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. 2010 Chem. Biol. Interact. pmid:20079722
Rowe AH et al. Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation. 2003 Circ. Res. pmid:14512442
Fukunaga M et al. Mast cell death induced by 24(S),25-epoxycholesterol. 2010 Exp. Cell Res. pmid:20854813
Brown AJ 24(S),25-epoxycholesterol: a messenger for cholesterol homeostasis. 2009 Int. J. Biochem. Cell Biol. pmid:18725318
Javitt NB Alzheimer's disease: neuroprogesterone, epoxycholesterol, and ABC transporters as determinants of neurodesmosterol tissue levels and its role in amyloid protein processing. 2013 J. Alzheimers Dis. pmid:23455994
Saucier SE et al. Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts. 1985 J. Biol. Chem. pmid:4055791
Taylor FR et al. 24,25-Epoxysterol metabolism in cultured mammalian cells and repression of 3-hydroxy-3-methylglutaryl-CoA reductase. 1986 J. Biol. Chem. pmid:3771561
Lehmann JM et al. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. 1997 J. Biol. Chem. pmid:9013544
Spencer TA et al. 24(S),25-Epoxycholesterol. Evidence consistent with a role in the regulation of hepatic cholesterogenesis. 1985 J. Biol. Chem. pmid:4055739
Davies JD et al. Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells. 2005 J. Biol. Chem. pmid:15548517
Wong J et al. Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis. 2008 J. Biol. Chem. pmid:17981807
Gupta A et al. Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestinal epithelial cells. 1986 J. Biol. Chem. pmid:3722155
Panini SR et al. Regulation of sterol biosynthesis and of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in cultured cells by progesterone. 1987 J. Biol. Chem. pmid:3667583
Williams S et al. X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch. 2003 J. Biol. Chem. pmid:12736258
Kaneko E et al. Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. 2003 J. Biol. Chem. pmid:12847102
Beyea MM et al. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. 2007 J. Biol. Chem. pmid:17186944
Panini SR et al. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol. 1992 J. Biol. Chem. pmid:1618770
Nelson JA et al. Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide. 1981 J. Biol. Chem. pmid:7451488
Zapata-Gonzalez F et al. 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. 2007 J. Immunol. pmid:17475839
Kömüves LG et al. Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. 2002 J. Invest. Dermatol. pmid:11851872