Authors | Title | Published | Journal | PubMed Link |
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Nury T et al. | Biological activities of the LXRα and β agonist, 4β-hydroxycholesterol, and of its isomer, 4α-hydroxycholesterol, on oligodendrocytes: effects on cell growth and viability, oxidative and inflammatory status. | 2013 | Biochimie | pmid:23220593 |
Huang MQ et al. | Quantitation of P450 3A4 endogenous biomarker - 4β-hydroxycholesterol - in human plasma using LC/ESI-MS/MS. | 2014 | Biomed. Chromatogr. | pmid:24861746 |
Wide K et al. | Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy. | 2008 | Br J Clin Pharmacol | pmid:18279471 |
Gjestad C et al. | 4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation? | 2016 | Br J Clin Pharmacol | pmid:26574235 |
Gjestad C et al. | 4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients. | 2017 | Br J Clin Pharmacol | pmid:28585378 |
Vanhove T et al. | Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance. | 2016 | Br J Clin Pharmacol | pmid:27501475 |
Mårde Arrhén Y et al. | A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction. | 2013 | Br J Clin Pharmacol | pmid:23116409 |
Vanhove T et al. | Pretransplant 4β-hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation. | 2017 | Br J Clin Pharmacol | pmid:28603840 |
Diczfalusy U et al. | 4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans. | 2011 | Br J Clin Pharmacol | pmid:21219398 |
Diczfalusy U et al. | 4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin. | 2009 | Br J Clin Pharmacol | pmid:19006545 |