Authors | Title | Published | Journal | PubMed Link |
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Kanebratt KP et al. | Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol. | 2008 | Clin. Pharmacol. Ther. | pmid:18650803 |
Lütjohann D et al. | 4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man. | 2009 | Int J Clin Pharmacol Ther | pmid:19954708 |
Tomalik-Scharte D et al. | Plasma 4beta-hydroxycholesterol: an endogenous CYP3A metric? | 2009 | Clin. Pharmacol. Ther. | pmid:19458613 |
Honda A et al. | Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. | 2009 | J. Lipid Res. | pmid:18815436 |
Allmyr M et al. | Human exposure to triclosan via toothpaste does not change CYP3A4 activity or plasma concentrations of thyroid hormones. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19686543 |
Diczfalusy U et al. | 4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin. | 2009 | Br J Clin Pharmacol | pmid:19006545 |
Yang Z and Rodrigues AD | Does the long plasma half-life of 4beta-hydroxycholesterol impact its utility as a cytochrome P450 3A (CYP3A) metric? | 2010 | J Clin Pharmacol | pmid:20197489 |
Goodenough AK et al. | Quantification of 4-beta-hydroxycholesterol in human plasma using automated sample preparation and LC-ESI-MS/MS analysis. | 2011 | Chem. Res. Toxicol. | pmid:21728364 |
Peters J et al. | Oral absorption of clarithromycin is nearly abolished by chronic comedication of rifampicin in foals. | 2011 | Drug Metab. Dispos. | pmid:21690264 |
Diczfalusy U et al. | 4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans. | 2011 | Br J Clin Pharmacol | pmid:21219398 |