Authors | Title | Published | Journal | PubMed Link |
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Woolsey SJ et al. | Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P450 3A Activity and Single-Time-Point Oral Midazolam Microdose Phenotype in Healthy Subjects. | 2016 | Basic Clin. Pharmacol. Toxicol. | pmid:26399557 |
de Graan AJ et al. | 4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes. | 2015 | Br J Clin Pharmacol | pmid:26119961 |
Hukkanen J et al. | The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity. | 2015 | Br J Clin Pharmacol | pmid:26095142 |
Mannheimer B et al. | No impact of vitamin D on the CYP3A biomarker 4β-hydroxycholesterol in patients with abnormal glucose regulation. | 2015 | PLoS ONE | pmid:25835492 |
Ngaimisi E et al. | Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment. | 2014 | J. Antimicrob. Chemother. | pmid:25096076 |
Huang MQ et al. | Quantitation of P450 3A4 endogenous biomarker - 4β-hydroxycholesterol - in human plasma using LC/ESI-MS/MS. | 2014 | Biomed. Chromatogr. | pmid:24861746 |
Dutreix C et al. | Comparison of two endogenous biomarkers of CYP3A4 activity in a drug-drug interaction study between midostaurin and rifampicin. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24839948 |
Kasichayanula S et al. | Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects. | 2014 | Br J Clin Pharmacol | pmid:24837659 |
Nylén H et al. | Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives. | 2014 | Basic Clin. Pharmacol. Toxicol. | pmid:24655660 |
Li K et al. | 4β-Hydroxycholesterol as an endogenous biomarker of CYP3A activity in cynomolgus monkeys. | 2014 | Drug Metab. Dispos. | pmid:24595680 |