Nguyen PN et al. |
Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep. |
2003 |
Pediatr. Res. |
pmid:12646725
|
Mazen I et al. |
Molecular analysis of 5alpha-reductase type 2 gene in eight unrelated egyptian children with suspected 5alpha-reductase deficiency: prevalence of the G34R mutation. |
2003 |
Clin. Endocrinol. (Oxf) |
pmid:12699446
|
Sung YM et al. |
Re: Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men. |
2003 |
J. Natl. Cancer Inst. |
pmid:12671025
|
Martin RM et al. |
Familial hyperestrogenism in both sexes: clinical, hormonal, and molecular studies of two siblings. |
2003 |
J. Clin. Endocrinol. Metab. |
pmid:12843139
|
Johnson DC and Widlanski TS |
Cerium(III) chloride-mediated reactions of sulfonamide dianions. |
2003 |
J. Org. Chem. |
pmid:12816492
|
Ji Q et al. |
Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism. |
2003 |
Prostate |
pmid:12539226
|
Fassnacht M et al. |
Beyond adrenal and ovarian androgen generation: Increased peripheral 5 alpha-reductase activity in women with polycystic ovary syndrome. |
2003 |
J. Clin. Endocrinol. Metab. |
pmid:12788885
|
Faragalla J et al. |
Comparative pharmacophore development for inhibitors of human and rat 5-alpha-reductase. |
2003 |
J. Mol. Graph. Model. |
pmid:12798393
|
Li Z et al. |
Association of V89L SRD5A2 polymorphism with prostate cancer development in a Japanese population. |
2003 |
J. Urol. |
pmid:12771801
|
Chang BL et al. |
Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer. |
2003 |
Prostate |
pmid:12746845
|
Bairamov AA and Sapronov NS |
Effect of dehydroepiandrosterone on radioligand binding of [3H]-testosterone by androgen receptors in rat hypothalamus. |
2004 |
Bull. Exp. Biol. Med. |
pmid:15665952
|
Finn DA et al. |
The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches. |
2004 |
Pharmacol. Ther. |
pmid:14761701
|
Namazi MR |
Further insight into the pathomechanism of acne by considering the 5-alpha-reductase inhibitory effect of linoleic acid. |
2004 |
Int. J. Dermatol. |
pmid:15357760
|
Nguyen PN et al. |
Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion. |
2004 |
J. Physiol. (Lond.) |
pmid:15331682
|
Lee HH et al. |
Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells. |
2004 |
Carcinogenesis |
pmid:14963012
|
Siler U et al. |
Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model. |
2004 |
FASEB J. |
pmid:15084515
|
Assinder SJ et al. |
Regulation of 5alpha-reductase isoforms by oxytocin in the rat ventral prostate. |
2004 |
Endocrinology |
pmid:15358676
|
Ahn KW and Sampson NS |
Cholesterol oxidase senses subtle changes in lipid bilayer structure. |
2004 |
Biochemistry |
pmid:14730988
|
Seo DW et al. |
Oxysterols from human bile induce apoptosis of canine gallbladder epithelial cells in monolayer culture. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:15246959
|
Rontani JF and Aubert C |
Electron ionization mass spectral fragmentation of derivatized 4,5- and 5,6-epoxysterols. |
2004 |
Rapid Commun. Mass Spectrom. |
pmid:15116422
|
Chapple CR |
Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician. |
2004 |
BJU Int. |
pmid:15329091
|
McInnes KJ et al. |
5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor. |
2004 |
J. Biol. Chem. |
pmid:15044432
|
Frye CA et al. |
Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase. |
2004 |
Brain Res. |
pmid:15033426
|
Dalla Valle L et al. |
Expression of cytochrome P450c17 and other steroid-converting enzymes in the rat kidney throughout the life-span. |
2004 |
J. Steroid Biochem. Mol. Biol. |
pmid:15261307
|
Clark RV et al. |
Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5alpha-reductase inhibitor. |
2004 |
J. Clin. Endocrinol. Metab. |
pmid:15126539
|
McVey MJ et al. |
Altered testicular microsomal steroidogenic enzyme activities in rats with lifetime exposure to soy isoflavones. |
2004 |
J. Steroid Biochem. Mol. Biol. |
pmid:15698548
|
Mathur S et al. |
Evaluation of cell permeation of a potent 5alpha-reductase inhibitor using MALDI-TOF MS. |
2004 |
J Enzyme Inhib Med Chem |
pmid:15648657
|
Palusinski R and Barud W |
Proscar and propecia--a therapeutic perspective. |
2004 |
J. Clin. Endocrinol. Metab. |
pmid:15579805
|
Aissaoui A et al. |
Novel cationic lipids incorporating an acid-sensitive acylhydrazone linker: synthesis and transfection properties. |
2004 |
J. Med. Chem. |
pmid:15456264
|
Zhu HJ and Sacchetti M |
Solubilization and solid-state characterization of a poorly soluble 5-alpha reductase inhibitor. |
2004 |
Drug Dev Ind Pharm |
pmid:15285330
|
Foley CL et al. |
An update on the use of 5alpha-reductase inhibitors. |
2004 |
Drugs Today |
pmid:15148530
|
Hernandez J et al. |
The potential role of cyclooxygenase-2 inhibitors and 5alpha-reductase inhibitors in the prevention of urologic conditions. |
2004 |
Urol. Clin. North Am. |
pmid:15123401
|
Libecco JF and Bergfeld WF |
Finasteride in the treatment of alopecia. |
2004 |
Expert Opin Pharmacother |
pmid:15102575
|
Marberger M et al. |
Optimising the medical management of benign prostatic hyperplasia. |
2004 |
Eur. Urol. |
pmid:15041103
|
Brown GA and Sussman DO |
A current review of medical therapy for benign prostatic hyperplasia. |
2004 |
J Am Osteopath Assoc |
pmid:15038398
|
Gonzales E et al. |
SRD5B1 (AKR1D1) gene analysis in delta(4)-3-oxosteroid 5beta-reductase deficiency: evidence for primary genetic defect. |
2004 |
J. Hepatol. |
pmid:15030995
|
Goodman PJ et al. |
Implementation of the Prostate Cancer Prevention Trial (PCPT). |
2004 |
Control Clin Trials |
pmid:15020037
|
Leyden J et al. |
A systemic type I 5 alpha-reductase inhibitor is ineffective in the treatment of acne vulgaris. |
2004 |
J. Am. Acad. Dermatol. |
pmid:14988688
|
Schmidt LJ et al. |
Gene expression in prostate cancer cells treated with the dual 5 alpha-reductase inhibitor dutasteride. |
2004 Nov-Dec |
J. Androl. |
pmid:15477368
|
Al-Mutair A et al. |
Cytogenetics and etiology of ambiguous genitalia in 120 pediatric patients. |
2004 Sep-Oct |
Ann Saudi Med |
pmid:15573851
|
Beattie ME et al. |
Sterol structure determines miscibility versus melting transitions in lipid vesicles. |
2005 |
Biophys. J. |
pmid:15951379
|
Iranmanesh A and Veldhuis JD |
Combined inhibition of types I and II 5 alpha-reductase selectively augments the basal (nonpulsatile) mode of testosterone secretion in young men. |
2005 |
J. Clin. Endocrinol. Metab. |
pmid:15811930
|
Bratoeff E et al. |
Recent advances in the chemistry and pharmacological activity of new steroidal antiandrogens and 5 alpha-reductase inhibitors. |
2005 |
Curr. Med. Chem. |
pmid:15853706
|
Pérez-Ornelas V et al. |
New 5alpha-reductase inhibitors: in vitro and in vivo effects. |
2005 |
Steroids |
pmid:15763601
|
Pucadyil TJ et al. |
Membrane cholesterol oxidation inhibits ligand binding function of hippocampal serotonin(1A) receptors. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15850776
|
Borst SE et al. |
Inhibition of 5alpha-reductase blocks prostate effects of testosterone without blocking anabolic effects. |
2005 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:15367394
|
Hammer F et al. |
Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging. |
2005 |
J. Clin. Endocrinol. Metab. |
pmid:16091484
|
Wakisaka N et al. |
Effectiveness of finasteride on patients with male pattern baldness who have different androgen receptor gene polymorphism. |
2005 |
J. Investig. Dermatol. Symp. Proc. |
pmid:16382684
|
Livingstone DE et al. |
Increased A-ring reduction of glucocorticoids in obese Zucker rats: effects of insulin sensitization. |
2005 |
Obes. Res. |
pmid:16222053
|
Caldinelli L et al. |
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin. |
2005 |
J. Biol. Chem. |
pmid:15817448
|
Evans CP et al. |
An evidence-based approach to understanding the pharmacological class effect in the management of prostatic diseases. |
2005 |
BJU Int. |
pmid:15794775
|
Ellis JA et al. |
Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1. |
2005 |
J. Hum. Genet. |
pmid:16155734
|
Wiebe JP et al. |
The role of progesterone metabolites in breast cancer: potential for new diagnostics and therapeutics. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15860263
|
Matthiesson KL et al. |
Novel male hormonal contraceptive combinations: the hormonal and spermatogenic effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist. |
2005 |
J. Clin. Endocrinol. Metab. |
pmid:15509637
|
Panter BU et al. |
5alpha-reductase in human embryonic kidney cell line HEK293: evidence for type II enzyme expression and activity. |
2005 |
Mol. Cell. Biochem. |
pmid:15792368
|
Puglielli L et al. |
Alzheimer disease beta-amyloid activity mimics cholesterol oxidase. |
2005 |
J. Clin. Invest. |
pmid:16127459
|
Sandhu JS and Vaughan ED |
Combination therapy for the pharmacological management of benign prostatic hyperplasia: rationale and treatment options. |
2005 |
Drugs Aging |
pmid:16323969
|
Lewis JG et al. |
Circulating levels of isoflavones and markers of 5alpha-reductase activity are higher in Japanese compared with New Zealand males: what is the role of circulating steroids in prostate disease? |
2005 |
Steroids |
pmid:16137729
|
Barocas DA et al. |
Five-alpha-reductase expression in benign and malignant urothelium: correlation with disease characteristics and outcome. |
2005 |
Urology |
pmid:16286153
|
Andriole G et al. |
The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge. |
2005 |
J. Urol. |
pmid:16280736
|
Ordyan NE and Pivina SG |
Effects of prenatal stress on the activity of an enzyme involved in neurosteroid synthesis during the "critical period" of sexual differentiation of the brain in male rats. |
2005 |
Neurosci. Behav. Physiol. |
pmid:16270175
|
Kiyokage E et al. |
Localization of 5alpha-reductase in the rat main olfactory bulb. |
2005 |
J. Comp. Neurol. |
pmid:16261538
|
Tiwari A et al. |
Benign prostatic hyperplasia: an insight into current investigational medical therapies. |
2005 |
Expert Opin Investig Drugs |
pmid:16255676
|
Fujita R et al. |
Anti-androgenic activities of Ganoderma lucidum. |
2005 |
J Ethnopharmacol |
pmid:16029938
|
Rosati F et al. |
5alpha-Reductase activity in Lycopersicon esculentum: cloning and functional characterization of LeDET2 and evidence of the presence of two isoenzymes. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15993049
|
Gorin RE et al. |
Effects of finasteride on chronic and acute ethanol withdrawal severity in the WSP and WSR selected lines. |
2005 |
Alcohol. Clin. Exp. Res. |
pmid:15976519
|
Monte MJ et al. |
Transient changes in the expression pattern of key enzymes for bile acid synthesis during rat liver regeneration. |
2005 |
Biochim. Biophys. Acta |
pmid:15904869
|
Vallarino M et al. |
Ontogeny of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the frog brain. |
2005 |
Ann. N. Y. Acad. Sci. |
pmid:15891098
|
Rho SS et al. |
The hair growth promoting effect of Asiasari radix extract and its molecular regulation. |
2005 |
J. Dermatol. Sci. |
pmid:15862941
|
Luu-The V et al. |
Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15860270
|
Monte MJ et al. |
Changes in the expression of genes related to bile acid synthesis and transport by the rat liver during hepatocarcinogenesis. |
2005 |
Clin. Sci. |
pmid:15853769
|
Souverein PC et al. |
Treatment of benign prostatic hyperplasia and occurrence of prostatic surgery and acute urinary retention: a population-based cohort study in the Netherlands. |
2005 |
Eur. Urol. |
pmid:15774250
|
Haeffner F et al. |
Model studies of cholesterol and ascorbate oxidation by copper complexes: relevance to Alzheimer's disease beta-amyloid metallochemistry. |
2005 |
J. Inorg. Biochem. |
pmid:16271394
|
Festuccia C et al. |
Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells. |
2005 |
J. Cancer Res. Clin. Oncol. |
pmid:15650886
|
Papanikolaou A et al. |
Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39. |
2005 |
J. Biol. Chem. |
pmid:15890655
|
Guzmán DC et al. |
Effect of testosterone and steroids homologues on indolamines and lipid peroxidation in rat brain. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15857756
|
Cabeza M et al. |
New progesterone derivatives as inhibitors of 5alpha-reductase enzyme and prostate cancer cell growth. |
2006 |
J Enzyme Inhib Med Chem |
pmid:17059168
|
Stine KJ et al. |
Interaction of the glycoalkaloid tomatine with DMPC and sterol monolayers studied by surface pressure measurements and Brewster angle microscopy. |
2006 |
J Phys Chem B |
pmid:17078662
|
Patel S and Mishra BK |
Oxidation of cholesterol by a biomimetic oxidant, cetyltrimethylammonium dichromate. |
2006 |
J. Org. Chem. |
pmid:16626135
|
Huang YF et al. |
One new anthraquinone from marine Streptomyces sp. FX-58. |
2006 |
Nat. Prod. Res. |
pmid:17127510
|
Sánchez P et al. |
Effects of testosterone on brain mRNA levels of steroid 5alpha-reductase isozymes in early postnatal life of rat. |
2006 |
Neurochem. Int. |
pmid:16828201
|
Sobel V et al. |
Bone mineral density in the complete androgen insensitivity and 5alpha-reductase-2 deficiency syndromes. |
2006 |
J. Clin. Endocrinol. Metab. |
pmid:16735493
|
Rebolj K et al. |
Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers. |
2006 |
Biochim. Biophys. Acta |
pmid:16857161
|
Grinthal A and Guidotti G |
CD39, NTPDase 1, is attached to the plasma membrane by two transmembrane domains. Why? |
2006 |
Purinergic Signal. |
pmid:18404478
|
Rojo L et al. |
Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease. |
2006 |
J. Biomed. Biotechnol. |
pmid:17047312
|
Lim L et al. |
Structural and kinetic analyses of the H121A mutant of cholesterol oxidase. |
2006 |
Biochem. J. |
pmid:16856877
|
Finn DA et al. |
A new look at the 5alpha-reductase inhibitor finasteride. |
2006 |
CNS Drug Rev |
pmid:16834758
|
Zhu YS and Cai LQ |
Effects of male sex hormones on gender identity, sexual behavior, and cognitive function. |
2006 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:16706106
|
Maria McCrohan A et al. |
Effects of the dual 5 alpha-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines. |
2006 |
Cancer |
pmid:16703599
|
Rouquette-Jazdanian AK et al. |
Revaluation of the role of cholesterol in stabilizing rafts implicated in T cell receptor signaling. |
2006 |
Cell. Signal. |
pmid:15925486
|
Liu J et al. |
5alpha-reductase inhibitory effect of triterpenoids isolated from Ganoderma lucidum. |
2006 |
Biol. Pharm. Bull. |
pmid:16462054
|
Naslund MJ et al. |
Managing enlarged prostate in primary care. |
2006 |
Int. J. Clin. Pract. |
pmid:17109668
|
Kim CI et al. |
Long-term results of medical treatment in benign prostatic hyperplasia. |
2006 |
Urology |
pmid:17095071
|
Hall MC |
The effect of oxysterols, individually and as a representative mixture from food, on in vitro cultured bovine ovarian granulosa cells. |
2006 |
Mol. Cell. Biochem. |
pmid:16983501
|
Norg RJ et al. |
A decision aid for GPs for the treatment of elderly male patients with lower urinary tract symptoms (LUTS). |
2006 |
Fam Pract |
pmid:16971394
|
Ekinci S et al. |
Sigmoid colon vaginoplasty in children. |
2006 |
Eur J Pediatr Surg |
pmid:16909357
|
Randall VA et al. |
New dimensions in Hirsutism. |
2006 |
Lasers Med Sci |
pmid:16874541
|
Marks LS et al. |
The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: a review and clinical recommendations. |
2006 |
J. Urol. |
pmid:16890642
|
Pitts WR |
Re: The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge. |
2006 |
J. Urol. |
pmid:16753453
|
Frye SV |
Discovery and clinical development of dutasteride, a potent dual 5alpha-reductase inhibitor. |
2006 |
Curr Top Med Chem |
pmid:16719800
|