| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yoshimoto T et al. | Polyethylene glycol derivative-modified cholesterol oxidase soluble and active in benzene. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3479986 |
| Kaul HK et al. | Genotoxicity of two fecal steroids in murine colonic epithelium assessed by the sister chromatid exchange technique. | 1987 | Mutagenesis | pmid:3328036 |
| Batta AK et al. | Chromatographic separation of putative precursors of cholestanol. | 1988 Jul-Aug | Steroids | pmid:3247666 |
| Ghosh S et al. | Cholesterol-oxidase-magnetic nanobioconjugates for the production of 4-cholesten-3-one and 4-cholesten-3, 7-dione. | 2018 | Bioresour. Technol. | pmid:29413944 |
| Donato LJ et al. | Description of analytical method and clinical utility of measuring serum 7-alpha-hydroxy-4-cholesten-3-one (7aC4) by mass spectrometry. | 2018 | Clin. Biochem. | pmid:29051033 |
| Ma J et al. | 4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1. | 2016 | Cell Death Dis | pmid:27899819 |
| Chen CL et al. | Cholest-4-en-3-one attenuates TGF-β responsiveness by inducing TGF-β receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells. | 2017 | J. Recept. Signal Transduct. Res. | pmid:27401208 |
| Mouzaki M et al. | Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease. | 2016 | PLoS ONE | pmid:27203081 |
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| Chen L et al. | A new ent-kaurane diterpenoid from Ixora amplexicaulis. | 2016 | Nat. Prod. Res. | pmid:25941744 |
4-Cholesten-3-one
4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 4-Cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-Cholesten-3-one?
4-Cholesten-3-one is suspected in Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana, Xanthoma, Rare Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Biochem. J. (1)
- J. Biol. Chem. (1)
- J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (1)
- Others (3)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 4-Cholesten-3-one
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 4-Cholesten-3-one through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-Cholesten-3-one?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Biol. Chem. (2)
- J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (1)
- J. Lipid Res. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-Cholesten-3-one?
There are no associated biomedical information in the current reference collection.