| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wijnberg JB and de Groot A | Synthesis and 13C-NMR analysis of 5 alpha- and 5 beta-cholestane-3,6-dione. | 1989 | Steroids | pmid:2588307 |
| Chen M et al. | The rate-determining steps of aldo-keto reductases (AKRs), a study on human steroid 5β-reductase (AKR1D1). | 2015 | Chem. Biol. Interact. | pmid:25500266 |
| Lin CW et al. | Substrate uptake and subcellular compartmentation of anoxic cholesterol catabolism in Sterolibacterium denitrificans. | 2015 | J. Biol. Chem. | pmid:25418128 |
| Walters JR et al. | The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid. | 2015 | Aliment. Pharmacol. Ther. | pmid:25329562 |
| Neuvonen M et al. | Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. | 2014 | PLoS ONE | pmid:25157633 |
| Bouvaine S et al. | A dietary test of putative deleterious sterols for the aphid Myzus persicae. | 2014 | PLoS ONE | pmid:24465993 |
| Benesch MG et al. | A DSC and FTIR spectroscopic study of the effects of the epimeric 4-cholesten-3-ols and 4-cholesten-3-one on the thermotropic phase behaviour and organization of dipalmitoylphosphatidylcholine bilayer membranes: comparison with their 5-cholesten analogues. | 2014 | Chem. Phys. Lipids | pmid:24296232 |
| GarcÃa-Fernández E et al. | A highly conserved mycobacterial cholesterol catabolic pathway. | 2013 | Environ. Microbiol. | pmid:23489718 |
| Gupta Y et al. | Kinetic analysis of LDL oxidation in IHD and IHD risk subjects in Indian population. | 2003 | Indian J Clin Biochem | pmid:23105369 |
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4-Cholesten-3-one
4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 4-Cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-Cholesten-3-one?
4-Cholesten-3-one is suspected in Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana, Xanthoma, Rare Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 4-Cholesten-3-one
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 4-Cholesten-3-one through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-Cholesten-3-one?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Biol. Chem. (2)
- Phytochemistry (1)
- J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-Cholesten-3-one?
There are no associated biomedical information in the current reference collection.