4-Cholesten-3-one

4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.

Cross Reference

Introduction

To understand associated biological information of 4-Cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-Cholesten-3-one?

4-Cholesten-3-one is suspected in Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana, Xanthoma, Rare Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 4-Cholesten-3-one

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 4-Cholesten-3-one through full-text articles, including metabolic pathways or pathways of biological mechanisms.

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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-Cholesten-3-one?

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What functions are associated with 4-Cholesten-3-one?


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Function Cross reference Weighted score Related literatures

What lipids are associated with 4-Cholesten-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-Cholesten-3-one?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-Cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-Cholesten-3-one

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Authors Title Published Journal PubMed Link
Aggarwal S et al. QSAR studies on human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroids. 2011 May-Jun Acta Pol Pharm pmid:21648201
Askarova S et al. Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes. 2011 Int J Alzheimers Dis pmid:21547213
Arellano Y et al. New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors. 2011 Steroids pmid:21729714
de Almeida CL et al. Bioactivities from marine algae of the genus Gracilaria. 2011 Int J Mol Sci pmid:21845096
Graupp M et al. Association of genetic variants in the two isoforms of 5α-reductase, SRD5A1 and SRD5A2, in lean patients with polycystic ovary syndrome. 2011 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:21530059
Kang HJ et al. The first successful paternity through in vitro fertilization-intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation. 2011 Fertil. Steril. pmid:21334614
Niu Y et al. Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy. 2011 Prostate pmid:21308715
Cha EK and Shariat SF The use of 5α-reductase inhibitors for the prevention and treatment of prostate cancer. 2011 Eur. Urol. pmid:21277077
Baudrand R et al. Overexpression of hepatic 5α-reductase and 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue is associated with hyperinsulinemia in morbidly obese patients. 2011 Metab. Clin. Exp. pmid:21704348
Mohler JL et al. Potential prostate cancer drug target: bioactivation of androstanediol by conversion to dihydrotestosterone. 2011 Clin. Cancer Res. pmid:21705451