4-Cholesten-3-one

4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.

Cross Reference

Introduction

To understand associated biological information of 4-Cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-Cholesten-3-one?

4-Cholesten-3-one is suspected in Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana, Xanthoma, Rare Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 4-Cholesten-3-one

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 4-Cholesten-3-one through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-Cholesten-3-one?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-Cholesten-3-one?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-Cholesten-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-Cholesten-3-one?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-Cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-Cholesten-3-one

Download all related citations
Per page 10 20 50 100 | Total 397
Authors Title Published Journal PubMed Link
Chang BL et al. Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer. 2003 Prostate pmid:12746845
Li Z et al. Association of V89L SRD5A2 polymorphism with prostate cancer development in a Japanese population. 2003 J. Urol. pmid:12771801
Norlin M et al. On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation. 2003 J. Lipid Res. pmid:12777473
Fassnacht M et al. Beyond adrenal and ovarian androgen generation: Increased peripheral 5 alpha-reductase activity in women with polycystic ovary syndrome. 2003 J. Clin. Endocrinol. Metab. pmid:12788885
Faragalla J et al. Comparative pharmacophore development for inhibitors of human and rat 5-alpha-reductase. 2003 J. Mol. Graph. Model. pmid:12798393
Johnson DC and Widlanski TS Cerium(III) chloride-mediated reactions of sulfonamide dianions. 2003 J. Org. Chem. pmid:12816492
Martin RM et al. Familial hyperestrogenism in both sexes: clinical, hormonal, and molecular studies of two siblings. 2003 J. Clin. Endocrinol. Metab. pmid:12843139
Sasaki G et al. Micropenis and the 5alpha-reductase-2 (SRD5A2) gene: mutation and V89L polymorphism analysis in 81 Japanese patients. 2003 J. Clin. Endocrinol. Metab. pmid:12843198
Ntais C et al. SRD5A2 gene polymorphisms and the risk of prostate cancer: a meta-analysis. 2003 Cancer Epidemiol. Biomarkers Prev. pmid:12869400
Soma KK et al. Brain aromatase, 5 alpha-reductase, and 5 beta-reductase change seasonally in wild male song sparrows: relationship to aggressive and sexual behavior. 2003 J. Neurobiol. pmid:12884261