4-Cholesten-3-one

4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.

Cross Reference

Introduction

To understand associated biological information of 4-Cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-Cholesten-3-one?

4-Cholesten-3-one is suspected in Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana, Xanthoma, Rare Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 4-Cholesten-3-one

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 4-Cholesten-3-one through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-Cholesten-3-one?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-Cholesten-3-one?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-Cholesten-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-Cholesten-3-one?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-Cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-Cholesten-3-one

Download all related citations
Per page 10 20 50 100 | Total 397
Authors Title Published Journal PubMed Link
Paris JJ et al. Inhibition of 5α-reductase activity in late pregnancy decreases gestational length and fecundity and impairs object memory and central progestogen milieu of juvenile rat offspring. 2011 J. Neuroendocrinol. pmid:21914008
Le Lay S et al. Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux. 2011 PLoS ONE pmid:21858084
Cai LQ et al. 17α-Estradiol and genistein inhibit high fat diet induced prostate gene expression and prostate growth in the rat. 2011 J. Urol. pmid:21855913
Chen L et al. [Active ingredients of Plastrum Testudinis inhibit epidermal stem cell apoptosis in serum-deprived culture]. 2011 Zhong Xi Yi Jie He Xue Bao pmid:21849150
de Almeida CL et al. Bioactivities from marine algae of the genus Gracilaria. 2011 Int J Mol Sci pmid:21845096
Lei H et al. [Sterols of marine bryozoan Bugula neritina from the South China Sea]. 2011 Zhong Yao Cai pmid:21823470
Arellano Y et al. New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors. 2011 Steroids pmid:21729714
Mohler JL et al. Potential prostate cancer drug target: bioactivation of androstanediol by conversion to dihydrotestosterone. 2011 Clin. Cancer Res. pmid:21705451
Baudrand R et al. Overexpression of hepatic 5α-reductase and 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue is associated with hyperinsulinemia in morbidly obese patients. 2011 Metab. Clin. Exp. pmid:21704348
Aggarwal S et al. QSAR studies on human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroids. 2011 May-Jun Acta Pol Pharm pmid:21648201