| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wu AH et al. | Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men. | 2001 | Cancer Epidemiol. Biomarkers Prev. | pmid:11352865 |
| Hsing AW et al. | Polymorphic markers in the SRD5A2 gene and prostate cancer risk: a population-based case-control study. | 2001 | Cancer Epidemiol. Biomarkers Prev. | pmid:11588134 |
| Suzuki K et al. | Characterization of cytotoxic steroids in human faeces and their putative role in the etiology of human colonic cancer. | 1986 | Cancer Lett. | pmid:3802059 |
| Lee HH et al. | Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells. | 2004 | Carcinogenesis | pmid:14963012 |
| Motola DL et al. | Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. | 2006 | Cell | pmid:16529801 |
| Ma J et al. | 4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1. | 2016 | Cell Death Dis | pmid:27899819 |
| Guardiola-Serrano F et al. | Palmitoylation of human FasL modulates its cell death-inducing function. | 2010 | Cell Death Dis | pmid:21368861 |
| Rouquette-Jazdanian AK et al. | Revaluation of the role of cholesterol in stabilizing rafts implicated in T cell receptor signaling. | 2006 | Cell. Signal. | pmid:15925486 |
| Liu J et al. | Anti-androgenic activity of fatty acids. | 2009 | Chem. Biodivers. | pmid:19353546 |
| Chen M et al. | The rate-determining steps of aldo-keto reductases (AKRs), a study on human steroid 5β-reductase (AKR1D1). | 2015 | Chem. Biol. Interact. | pmid:25500266 |
4-Cholesten-3-one
4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 4-Cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-Cholesten-3-one?
4-Cholesten-3-one is suspected in Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana, Xanthoma, Rare Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Biochem. J. (1)
- J. Biol. Chem. (1)
- J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (1)
- Others (3)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 4-Cholesten-3-one
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 4-Cholesten-3-one through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-Cholesten-3-one?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Biol. Chem. (2)
- J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (1)
- J. Lipid Res. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-Cholesten-3-one?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-Cholesten-3-one?
There are no associated biomedical information in the current reference collection.