Beasley CL et al. |
Reductions in cholesterol and synaptic markers in association cortex in mood disorders. |
2005 |
Bipolar Disord |
pmid:16176438
|
Lodeiro S et al. |
Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase. |
2005 |
J. Am. Chem. Soc. |
pmid:16218577
|
Davenport RJ |
How low can you go? |
2005 |
Sci Aging Knowledge Environ |
pmid:15772415
|
Chevy F et al. |
Sterol profiling of amniotic fluid: a routine method for the detection of distal cholesterol synthesis deficit. |
2005 |
Prenat. Diagn. |
pmid:16231320
|
Buurman ET et al. |
Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. |
2005 |
Antimicrob. Agents Chemother. |
pmid:15917573
|
Huff MW and Telford DE |
Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear. |
2005 |
Trends Pharmacol. Sci. |
pmid:15951028
|
Shao HJ et al. |
A new cytotoxic lanostane triterpenoid from the basidiomycete Hebeloma versipelle. |
2005 |
J. Antibiot. |
pmid:16506701
|
Cournia Z et al. |
A molecular mechanics force field for biologically important sterols. |
2005 |
J Comput Chem |
pmid:16028234
|
Ott RG et al. |
Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. |
2005 |
Biochim. Biophys. Acta |
pmid:15951236
|
Uthman A et al. |
Fluconazole upregulates sconC expression and inhibits sulphur metabolism in Microsporum canis. |
2005 |
Fungal Genet. Biol. |
pmid:15922636
|
Fink M et al. |
Cholesterogenic lanosterol 14alpha-demethylase (CYP51) is an immediate early response gene. |
2005 |
Endocrinology |
pmid:16123160
|
Suárez Y et al. |
Sterol stringency of proliferation and cell cycle progression in human cells. |
2005 |
Biochim. Biophys. Acta |
pmid:15904877
|
Barker KS et al. |
Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans. |
2004 |
J. Antimicrob. Chemother. |
pmid:15201233
|
Abe I et al. |
Enzymatic cyclization of 22,23-dihydro-2,3-oxidosqualene into euph-7-en-3beta-ol and bacchar-12-en-3beta-ol by recombinant beta-amyrin synthase. |
2004 |
J. Am. Chem. Soc. |
pmid:15025461
|
León F et al. |
Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells. |
2004 |
J. Nat. Prod. |
pmid:15620242
|
Thoma R et al. |
Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. |
2004 |
Nature |
pmid:15525992
|
Vieira LM et al. |
Bioactive friedolanostanes and 11(10-->8)-abeolanostanes from the bark of Garcinia speciosa. |
2004 |
J. Nat. Prod. |
pmid:15620248
|
Ruf A et al. |
The monotopic membrane protein human oxidosqualene cyclase is active as monomer. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14766201
|
Kuroda M et al. |
27-norlanostane glycosides from the bulbs of Muscari paradoxum. |
2004 |
J. Nat. Prod. |
pmid:15620262
|
Mouritsen OG and Zuckermann MJ |
What's so special about cholesterol? |
2004 |
Lipids |
pmid:15726825
|
Pan RL et al. |
Two new cyclolanostanol glycosides from the aerial parts of Cimicifuga foetida. |
2004 |
J Asian Nat Prod Res |
pmid:14989382
|
Javitt NB |
Oxysteroids: a new class of steroids with autocrine and paracrine functions. |
2004 |
Trends Endocrinol. Metab. |
pmid:15380811
|
Jabra-Rizk MA et al. |
Fungal biofilms and drug resistance. |
2004 |
Emerging Infect. Dis. |
pmid:15078591
|
Kavtaradze LK et al. |
A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures. |
2004 |
Steroids |
pmid:15465116
|
Godio RP et al. |
Agrobacterium tumefaciens-mediated transformation of the antitumor clavaric acid-producing basidiomycete Hypholoma sublateritium. |
2004 |
Curr. Genet. |
pmid:15480676
|
Wu X et al. |
New lanostane-type triterpenes from Fomes officinalis. |
2004 |
Chem. Pharm. Bull. |
pmid:15516768
|
Cragun DL et al. |
Undetectable maternal serum uE3 and postnatal abnormal sterol and steroid metabolism in Antley-Bixler syndrome. |
2004 |
Am. J. Med. Genet. A |
pmid:15266606
|
Wangun HV et al. |
Anti-inflammatory and anti-hyaluronate lyase activities of lanostanoids from Piptoporus betulinus. |
2004 |
J. Antibiot. |
pmid:15712671
|
Kudo M et al. |
Studies on the expression levels of sterol-metabolizing enzymes in the obese model SHR/NDmcr-cp rats. |
2004 |
Clin. Exp. Pharmacol. Physiol. |
pmid:15649292
|
Revankar SG et al. |
Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474487
|
Rezen T et al. |
New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transfer. |
2004 |
J. Mol. Evol. |
pmid:15383907
|
Lepesheva GI et al. |
CYP51 from Trypanosoma brucei is obtusifoliol-specific. |
2004 |
Biochemistry |
pmid:15311940
|
Adachi M et al. |
Compound heterozygous mutations of cytochrome P450 oxidoreductase gene (POR) in two patients with Antley-Bixler syndrome. |
2004 |
Am. J. Med. Genet. A |
pmid:15264278
|
Henriksen J et al. |
Vesicle fluctuation analysis of the effects of sterols on membrane bending rigidity. |
2004 |
Eur. Biophys. J. |
pmid:15221234
|
Sheng C et al. |
Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions. |
2004 |
J. Biomol. Struct. Dyn. |
pmid:15214809
|
Xie H et al. |
Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes. |
2004 |
Mol. Cell. Endocrinol. |
pmid:15130520
|
Lepesheva GI and Waterman MR |
CYP51--the omnipotent P450. |
2004 |
Mol. Cell. Endocrinol. |
pmid:15026190
|
Cotman M et al. |
A functional cytochrome P450 lanosterol 14 alpha-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols. |
2004 |
Endocrinology |
pmid:14630712
|
Zuckermann MJ et al. |
Modeling lipid-sterol bilayers: applications to structural evolution, lateral diffusion, and rafts. |
2004 |
Meth. Enzymol. |
pmid:15063652
|
Cao X et al. |
Meiosis-activating sterol synthesis in rat preovulatory follicle: is it involved in resumption of meiosis? |
2004 |
Biol. Reprod. |
pmid:15269103
|
Chen YG et al. |
Ananosic acids B and C, two new 18(13-->12)-abeo-lanostane triterpenoids from Kadsura ananosma. |
2004 |
J. Nat. Prod. |
pmid:15165154
|
Moodley N et al. |
Eucosterol-type nortriterpenoids from Merwilla natalensis. |
2004 |
J. Nat. Prod. |
pmid:15165167
|
Kavtaradze LK et al. |
Efficient routes to epimerically-pure side-chain derivatives of lanosterol. |
2004 |
Steroids |
pmid:15183688
|
Shim SH et al. |
New lanostane-type triterpenoids from Ganoderma applanatum. |
2004 |
J. Nat. Prod. |
pmid:15270562
|
Trösken ER et al. |
Quantitation of lanosterol and its major metabolite FF-MAS in an inhibition assay of CYP51 by azoles with atmospheric pressure photoionization based LC-MS/MS. |
2004 |
J. Am. Soc. Mass Spectrom. |
pmid:15276168
|
Dantas-Leite L et al. |
Selective anti-Toxoplasma gondii activities of azasterols. |
2004 |
Int. J. Antimicrob. Agents |
pmid:15194134
|
Hronská L et al. |
Low concentrations of the non-ionic detergent Nonidet P-40 interfere with sterol biogenesis and viability of the yeast Saccharomyces cerevisiae. |
2004 |
FEMS Microbiol. Lett. |
pmid:15336428
|
Woo KC et al. |
Phytoestrogen cimicifugoside-mediated inhibition of catecholamine secretion by blocking nicotinic acetylcholine receptor in bovine adrenal chromaffin cells. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:14757852
|
Montero MT et al. |
Geranylgeraniol regulates negatively caspase-1 autoprocessing: implication in the Th1 response against Mycobacterium tuberculosis. |
2004 |
J. Immunol. |
pmid:15470035
|
Kaneshiro ES |
Sterol metabolism in the opportunistic pathogen Pneumocystis: advances and new insights. |
2004 |
Lipids |
pmid:15638243
|
Berger A et al. |
Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. |
2004 |
Lipids Health Dis |
pmid:14969592
|
Adachi M et al. |
Abnormal steroidogenesis in three patients with Antley-Bixler syndrome: apparent decreased activity of 17alpha-hydroxylase, 17,20-lyase and 21-hydroxylase. |
2004 |
Pediatr Int |
pmid:15491389
|
Stocker A |
Molecular mechanisms of vitamin E transport. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15753133
|
Kojima M et al. |
Lead nitrate-induced development of hypercholesterolemia in rats: sterol-independent gene regulation of hepatic enzymes responsible for cholesterol homeostasis. |
2004 |
Toxicol. Lett. |
pmid:15475176
|
Ye X et al. |
Characterization of a human Sec14-like protein cDNA SEC14L3 highly homologous to human SPF/TAP. |
2004 |
Mol. Biol. Rep. |
pmid:15040456
|
Martin-Creuzburg D and Von Elert E |
Impact of 10 dietary sterols on growth and reproduction of Daphnia galeata. |
2004 |
J. Chem. Ecol. |
pmid:15139303
|
Fernández C et al. |
Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. |
2004 |
Exp. Cell Res. |
pmid:15383319
|
Nöllmann M et al. |
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin. |
2004 |
Biophys. J. |
pmid:15111427
|
Cantillo-Ciau Z et al. |
Two new 24-isopropenyl-lanostanoids from Tillandsia brachycaulos. |
2003 Sep-Oct |
Z. Naturforsch., C, J. Biosci. |
pmid:14577625
|
Tang YJ and Zhong JJ |
Scale-up of a liquid static culture process for hyperproduction of ganoderic acid by the medicinal mushroom Ganoderma lucidum. |
2003 Nov-Dec |
Biotechnol. Prog. |
pmid:14656165
|
Teunissen CE et al. |
Serum cholesterol, precursors and metabolites and cognitive performance in an aging population. |
2003 Jan-Feb |
Neurobiol. Aging |
pmid:12493560
|
Hess BA |
Formation of the C ring in the lanosterol biosynthesis from squalene. |
2003 |
Org. Lett. |
pmid:12529131
|
Zhao XH et al. |
[Studies on new trierpenoid constituents from the Rhizoma of Cimicifuga foetida]. |
2003 |
Zhongguo Zhong Yao Za Zhi |
pmid:15015286
|
Pan RL et al. |
[Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida]. |
2003 |
Zhongguo Zhong Yao Za Zhi |
pmid:15015306
|
Ori K et al. |
Lanosterol and tetranorlanosterol glycosides from the bulbs of Muscari paradoxum. |
2003 |
Phytochemistry |
pmid:14629999
|
Yamashita Y et al. |
Production of progesterone from de novo-synthesized cholesterol in cumulus cells and its physiological role during meiotic resumption of porcine oocytes. |
2003 |
Biol. Reprod. |
pmid:12606468
|
Buckner FS et al. |
Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. |
2003 |
Mol. Biochem. Parasitol. |
pmid:14599667
|
Lepesheva GI et al. |
Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function. |
2003 |
Biochemistry |
pmid:12885242
|
Cavalier-Smith T and Chao EE |
Phylogeny of choanozoa, apusozoa, and other protozoa and early eukaryote megaevolution. |
2003 |
J. Mol. Evol. |
pmid:12698292
|
Bruneau JM et al. |
Drug induced proteome changes in Candida albicans: comparison of the effect of beta(1,3) glucan synthase inhibitors and two triazoles, fluconazole and itraconazole. |
2003 |
Proteomics |
pmid:12627386
|
Morales IJ et al. |
Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12606318
|
Ji H et al. |
Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14alpha-demethylase of fungi. |
2003 |
J. Med. Chem. |
pmid:12570370
|
Rozenberg O et al. |
Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12615663
|
Debeljak N et al. |
Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51. |
2003 |
Arch. Biochem. Biophys. |
pmid:12464255
|
Fon Tacer K et al. |
Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation. |
2003 |
J. Steroid Biochem. Mol. Biol. |
pmid:12943732
|
Majumder PL et al. |
Triterpenoids from the orchids Agrostophyllum brevipes and Agrostophyllum callosum. |
2003 |
Phytochemistry |
pmid:12560031
|
Jackson CJ et al. |
Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12565899
|
Sakurai N et al. |
Antitumor agents 220. Antitumor-promoting effects of cimigenol and related compounds on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis. |
2003 |
Bioorg. Med. Chem. |
pmid:12614901
|
Hand RA et al. |
Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. |
2003 |
Eukaryotic Cell |
pmid:12684380
|
Mo C et al. |
In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. |
2003 |
Biochim. Biophys. Acta |
pmid:12842197
|
Honda Y et al. |
Revision and confirmation of the regiochemistry of isoxazoles derived from methyl oleanonate and lanost-8-en-3-one. Synthesis of a new lanostane triterpenoid with a cyano-enone functionality in ring A. |
2003 |
J. Org. Chem. |
pmid:12790619
|
Maurer-Stroh S et al. |
Protein prenyltransferases. |
2003 |
Genome Biol. |
pmid:12702202
|
Schulz-Gasch T and Stahl M |
Mechanistic insights into oxidosqualene cyclizations through homology modeling. |
2003 |
J Comput Chem |
pmid:12666166
|
Veen M et al. |
Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. |
2003 |
FEMS Yeast Res. |
pmid:14554200
|
Ohashi M et al. |
Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets. |
2003 |
J. Biol. Chem. |
pmid:12837764
|
Porter TD |
Supernatant protein factor and tocopherol-associated protein: an unexpected link between cholesterol synthesis and vitamin E (review). |
2003 |
J. Nutr. Biochem. |
pmid:12559471
|
Pikuleva I and Javitt NB |
Novel sterols synthesized via the CYP27A1 metabolic pathway. |
2003 |
Arch. Biochem. Biophys. |
pmid:14622972
|
Otte K et al. |
Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol. |
2003 |
Mol. Cell. Biol. |
pmid:12529392
|
Kamo T et al. |
Anti-inflammatory lanostane-type triterpene acids from Piptoporus betulinus. |
2003 |
J. Nat. Prod. |
pmid:12932134
|
Zheng YH et al. |
Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12824470
|
Kaneshiro ES |
Is Pneumocystis a plant? |
2002 Sep-Oct |
J. Eukaryot. Microbiol. |
pmid:12425523
|
Fang QH and Zhong JJ |
Two-stage culture process for improved production of ganoderic acid by liquid fermentation of higher fungus Ganoderma lucidum. |
2002 Jan-Feb |
Biotechnol. Prog. |
pmid:11822899
|
Lupetti A et al. |
Molecular basis of resistance to azole antifungals. |
2002 |
Trends Mol Med |
pmid:11815273
|
Zhou W et al. |
Evidence for multiple sterol methyl transferase pathways in Pneumocystis carinii. |
2002 |
Lipids |
pmid:12617472
|
Roberti R et al. |
Cloning and expression of sterol Delta 14-reductase from bovine liver. |
2002 |
Eur. J. Biochem. |
pmid:11784322
|
Pedretti A et al. |
Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking. |
2002 |
J. Med. Chem. |
pmid:11906287
|
González AG et al. |
New lanostanoids from the fungus Ganoderma concinna. |
2002 |
J. Nat. Prod. |
pmid:11908995
|
Heimark L et al. |
Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis. |
2002 |
J Mass Spectrom |
pmid:11921367
|
Kim GT et al. |
Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies. |
2002 |
Bioorg. Med. Chem. |
pmid:11886788
|
Milla P et al. |
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles. |
2002 |
J. Biol. Chem. |
pmid:11706015
|