Sandherr M and Maschmeyer G |
Pharmacology and metabolism of voriconazole and Posaconazole in the treatment of invasive aspergillosis: review of the literature. |
2011 |
Eur. J. Med. Res. |
pmid:21486727
|
Mayr A and Lass-Flörl C |
Epidemiology and antifungal resistance in invasive Aspergillosis according to primary disease: review of the literature. |
2011 |
Eur. J. Med. Res. |
pmid:21486729
|
Elmehdawi R |
Hypolipidemia: a word of caution. |
2008 |
Libyan J Med |
pmid:21499464
|
Ito R et al. |
Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases. |
2011 |
Org. Lett. |
pmid:21526825
|
Borecká S et al. |
Cdr2p contributes to fluconazole resistance in Candida dubliniensis clinical isolates. |
2011 |
Can. J. Microbiol. |
pmid:21542785
|
Askarova S et al. |
Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes. |
2011 |
Int J Alzheimers Dis |
pmid:21547213
|
Korstanje LJ et al. |
Effects of steroid molecules on the dynamical structure of dioleoylphosphatidylcholine and digalactosyldiacylglycerol bilayers. |
1990 |
Biochim. Biophys. Acta |
pmid:2155018
|
Singh A and Prasad R |
Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints. |
2011 |
PLoS ONE |
pmid:21559392
|
Nowosielski M and Hoffmann M |
Do the substituent effects affect conformational freedom of squalene in hopene biosynthesis? |
2011 |
J Mol Model |
pmid:21562825
|
Nkinin SW et al. |
Pneumocystis carinii sterol 14α-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry. |
2011 Jul-Aug |
J. Eukaryot. Microbiol. |
pmid:21569162
|
Sheng C et al. |
Structure-based design, synthesis, and antifungal activity of new triazole derivatives. |
2011 |
Chem Biol Drug Des |
pmid:21585708
|
Vargas FA et al. |
Expanding a dynamic flux balance model of yeast fermentation to genome-scale. |
2011 |
BMC Syst Biol |
pmid:21595919
|
Tripodi KE et al. |
Role of heme and heme-proteins in trypanosomatid essential metabolic pathways. |
2011 |
Enzyme Res |
pmid:21603276
|
Visbal G et al. |
Synthesis, in vitro antifungal activity and mechanism of action of four sterol hydrazone analogues against the dimorphic fungus Paracoccidioides brasiliensis. |
|
Steroids |
pmid:21605581
|
Zhang XQ et al. |
Triterpenoids with neurotrophic activity from Ganoderma lucidum. |
2011 |
Nat. Prod. Res. |
pmid:21671206
|
Spitzer M et al. |
Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. |
2011 |
Mol. Syst. Biol. |
pmid:21694716
|
Ianas V et al. |
Role of posaconazole in the treatment of oropharyngeal candidiasis. |
2010 |
Infect Drug Resist |
pmid:21694893
|
Lat A and Thompson GR |
Update on the optimal use of voriconazole for invasive fungal infections. |
2011 |
Infect Drug Resist |
pmid:21694908
|
Elias PM et al. |
Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders. |
2011 |
Dermatoendocrinol |
pmid:21695019
|
Alvarez-Rueda N et al. |
Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance. |
2011 |
PLoS ONE |
pmid:21698128
|
Keber R et al. |
Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome. |
2011 |
J. Biol. Chem. |
pmid:21705796
|
Billheimer JT and Gaylor JL |
Effect of lipid composition on the transfer of sterols mediated by non-specific lipid transfer protein (sterol carrier protein2). |
1990 |
Biochim. Biophys. Acta |
pmid:2171663
|
Jiang Y et al. |
Synthesis, in vitro evaluation and molecular docking studies of new triazole derivatives as antifungal agents. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21737273
|
Mullins JG et al. |
Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola. |
2011 |
PLoS ONE |
pmid:21738598
|
Chadwick W et al. |
Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. |
2011 |
PLoS ONE |
pmid:21738745
|
Sangshetti JN et al. |
Synthesis, antifungal activity, and docking study of some new 1,2,4-triazole analogs. |
2011 |
Chem Biol Drug Des |
pmid:21752200
|
Paller AS et al. |
Pathogenesis-based therapy reverses cutaneous abnormalities in an inherited disorder of distal cholesterol metabolism. |
2011 |
J. Invest. Dermatol. |
pmid:21753784
|
Leichner GS et al. |
Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. |
2011 |
J. Biol. Chem. |
pmid:21778231
|
Sang ZG et al. |
[Studies on the secondary metabolites of Coriolopsis sp. G066]. |
2011 |
Zhong Yao Cai |
pmid:21809540
|
Oliaro-Bosso S et al. |
Characterization of the channel constriction allowing the access of the substrate to the active site of yeast oxidosqualene cyclase. |
2011 |
PLoS ONE |
pmid:21811565
|
Lim L et al. |
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease. |
2012 |
Cell Death Differ. |
pmid:21818119
|
Choi MH et al. |
Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. |
2011 |
BMC Cancer |
pmid:21824401
|
Cabrito TR et al. |
The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance. |
2011 |
Biochem. J. |
pmid:21831043
|
Marco-Jiménez F et al. |
Effect of lanosterol on the in vitro maturation in semi-defined culture system of prepubertal ewe oocytes. |
2014 |
Zygote |
pmid:21838962
|
Pfaller MA et al. |
Effects of terconazole and other azole antifungal agents on the sterol and carbohydrate composition of Candida albicans. |
1990 Jan-Feb |
Diagn. Microbiol. Infect. Dis. |
pmid:2184984
|
Shackleton CH |
Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesis. |
2012 |
Lipids |
pmid:21874273
|
Horvath SE et al. |
Metabolic link between phosphatidylethanolamine and triacylglycerol metabolism in the yeast Saccharomyces cerevisiae. |
2011 |
Biochim. Biophys. Acta |
pmid:21875690
|
Nes WD |
Biosynthesis of cholesterol and other sterols. |
2011 |
Chem. Rev. |
pmid:21902244
|
Cantu D et al. |
Next generation sequencing provides rapid access to the genome of Puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust. |
2011 |
PLoS ONE |
pmid:21909385
|
Stottmann RW et al. |
Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo. |
2011 |
PLoS Genet. |
pmid:21912524
|
Reynaud EG and Devos DP |
Transitional forms between the three domains of life and evolutionary implications. |
2011 |
Proc. Biol. Sci. |
pmid:21920985
|
Gleason JE et al. |
Analysis of hypoxia and hypoxia-like states through metabolite profiling. |
2011 |
PLoS ONE |
pmid:21931840
|
Krueger KP and Nelson AC |
Economic considerations in the treatment of invasive aspergillosis: a review of voriconazole pharmacoeconomic studies. |
2009 |
Clinicoecon Outcomes Res |
pmid:21935305
|
Leichtle AB et al. |
Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men. |
2011 |
Am. J. Clin. Nutr. |
pmid:21940598
|
Jensen PA et al. |
TIGER: Toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks. |
2011 |
BMC Syst Biol |
pmid:21943338
|
Hoot SJ et al. |
The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity. |
2011 |
BMC Microbiol. |
pmid:21951709
|
Nacev BA and Liu JO |
Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole. |
2011 |
PLoS ONE |
pmid:21969860
|
Targett-Adams P et al. |
Lipid metabolism and HCV infection. |
2010 |
Viruses |
pmid:21994676
|
Boone LR et al. |
Mechanism of resistance to dietary cholesterol. |
2011 |
J Lipids |
pmid:22007308
|
Wang X et al. |
Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci on chromosomes 3q25-26 and 21q22. |
2011 |
PLoS ONE |
pmid:22022364
|
Kaddurah-Daouk R et al. |
Enteric microbiome metabolites correlate with response to simvastatin treatment. |
2011 |
PLoS ONE |
pmid:22022402
|
Jiang J et al. |
Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:22033405
|
Choi KY et al. |
Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase. |
2012 |
Biotechnol. Bioeng. |
pmid:22038382
|
Wang JL et al. |
Enhanced recovery of antitumor ganoderic acid T from Ganoderma lucidum mycelia by novel chemical conversion strategy. |
2012 |
Biotechnol. Bioeng. |
pmid:22038732
|
Kennedy EM et al. |
Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. |
2011 |
J. Nat. Prod. |
pmid:22044278
|
Weeks AC et al. |
Identification and potency of cyclodextrin-lipid inhibitors of Staphylococcus aureus α-toxin. |
2012 |
Curr. Eye Res. |
pmid:22050601
|
Baumann K et al. |
Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris. |
2011 |
Microb. Cell Fact. |
pmid:22050768
|
Wang N et al. |
N-Cyclo-propyl-N-[2-(2,4-difluoro-phen-yl)-2-hy-droxy-1-(1H-1,2,4-triazol-1-yl)prop-yl]-2-(5-methyl-2,4-dioxo-1,2,3,4-tetra-hydro-pyrimidin-1-yl)acetamide dichloro-methane 0.62-solvate. |
2011 |
Acta Crystallogr Sect E Struct Rep Online |
pmid:22059025
|
Yadav VR et al. |
Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. |
2010 |
Toxins (Basel) |
pmid:22069560
|
Dutra RC et al. |
Preventive and therapeutic euphol treatment attenuates experimental colitis in mice. |
2011 |
PLoS ONE |
pmid:22073270
|
Chauvigné F et al. |
Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis. |
2011 |
PLoS ONE |
pmid:22087261
|
Vazquez JA |
Optimal management of oropharyngeal and esophageal candidiasis in patients living with HIV infection. |
2010 |
HIV AIDS (Auckl) |
pmid:22096388
|
Semighini CP et al. |
Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner. |
2011 |
PLoS Pathog. |
pmid:22114551
|
Das J et al. |
Oral itraconazole for the treatment of severe seborrhoeic dermatitis. |
2011 Sep-Oct |
Indian J Dermatol |
pmid:22121267
|
Hargrove TY et al. |
Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol. |
2012 |
J. Lipid Res. |
pmid:22135275
|
Howell SA and Mallet AI |
A novel lanosterol isomer produced in response to azole antifungals. |
1990 |
J. Steroid Biochem. |
pmid:2214765
|
Shichiri M et al. |
A novel role for α-tocopherol transfer protein (α-TTP) in protecting against chloroquine toxicity. |
2012 |
J. Biol. Chem. |
pmid:22147702
|
Dutra RC et al. |
Euphol prevents experimental autoimmune encephalomyelitis in mice: evidence for the underlying mechanisms. |
2012 |
Biochem. Pharmacol. |
pmid:22155310
|
Nes CR et al. |
Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms. |
2012 |
Biochem. J. |
pmid:22176028
|
Vandeputte P et al. |
Antifungal resistance and new strategies to control fungal infections. |
2012 |
Int J Microbiol |
pmid:22187560
|
Alvarez-Vasquez F et al. |
Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae. |
2011 |
PLoS ONE |
pmid:22194828
|
Silbernagel G et al. |
Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humans. |
2012 |
Exp Diabetes Res |
pmid:22203835
|
Loper JC |
Cytochrome P450 lanosterol 14α-demethylase (CYP51): insights from molecular genetic analysis of the ERG11 gene in Saccharomyces cerevisiae. |
1992 |
J. Steroid Biochem. Mol. Biol. |
pmid:22217856
|
Lou HY et al. |
Hepatic failure related to itraconazole use successfully treated by corticosteroids. |
2011 |
Hepat Mon |
pmid:22224084
|
Chandrasekar SB et al. |
Phytopharmacology of Ficus religiosa. |
2010 |
Pharmacogn Rev |
pmid:22228961
|
Oh HG et al. |
Effects of Ficus carica paste on constipation induced by a high-protein feed and movement restriction in beagles. |
2011 |
Lab Anim Res |
pmid:22232635
|
Warrilow AG et al. |
S279 point mutations in Candida albicans Sterol 14-α demethylase (CYP51) reduce in vitro inhibition by fluconazole. |
2012 |
Antimicrob. Agents Chemother. |
pmid:22252802
|
Cook CC et al. |
Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. |
2012 |
Cell Death Dis |
pmid:22258408
|
Besga A et al. |
Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms. |
2012 |
Neurosci. Lett. |
pmid:22281444
|
Yun SJ et al. |
Aberrant phenotypes of transgenic mice expressing dimeric human erythropoietin. |
2012 |
Reprod. Biol. Endocrinol. |
pmid:22284751
|
Wang Y et al. |
Simultaneous determination of cimicifugoside H-2, cimicifugoside H-1, 23-epi-26-deoxyactein, cimigenol xyloside and 25-O-acetylcimigenoside in beagle dog plasma by LC-MS/MS. |
2012 |
J Pharm Biomed Anal |
pmid:22285707
|
Takishita K et al. |
Lateral transfer of tetrahymanol-synthesizing genes has allowed multiple diverse eukaryote lineages to independently adapt to environments without oxygen. |
2012 |
Biol. Direct |
pmid:22296756
|
Barker BM et al. |
Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. |
2012 |
BMC Genomics |
pmid:22309491
|
Clark PJ et al. |
Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. |
2012 |
Hepatology |
pmid:22318926
|
Kirchmair J et al. |
Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms. |
2012 |
J Chem Inf Model |
pmid:22339582
|
Kořený L et al. |
Aerobic kinetoplastid flagellate Phytomonas does not require heme for viability. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22355128
|
Fakheri RJ and Javitt NB |
27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols. |
2012 |
Steroids |
pmid:22366074
|
Liu RM et al. |
Cytotoxic and pro-apoptotic effects of novel ganoderic acid derivatives on human cervical cancer cells in vitro. |
2012 |
Eur. J. Pharmacol. |
pmid:22366428
|
Froufe HJ et al. |
Virtual screening of low molecular weight mushrooms compounds as potential Mdm2 inhibitors. |
2013 |
J Enzyme Inhib Med Chem |
pmid:22380771
|
Kosir R et al. |
Novel insights into the downstream pathways and targets controlled by transcription factors CREM in the testis. |
2012 |
PLoS ONE |
pmid:22384077
|
Campbell BC et al. |
Chemosensitization as a means to augment commercial antifungal agents. |
2012 |
Front Microbiol |
pmid:22393330
|
Snelders E et al. |
Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus. |
2012 |
PLoS ONE |
pmid:22396740
|
Desnos-Ollivier M et al. |
Antifungal susceptibility profiles of 1698 yeast reference strains revealing potential emerging human pathogens. |
2012 |
PLoS ONE |
pmid:22396754
|
Ngamskulrungroj P et al. |
Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans. |
2012 |
PLoS ONE |
pmid:22412978
|
Singh R et al. |
HILIC quantification of oenotheralanosterol A and B from Oenothera biennis and their suppression of IL-6 and TNF-α expression in mouse macrophages. |
2012 |
J Ethnopharmacol |
pmid:22414479
|
Howard AL et al. |
Sterol C24-methyltransferase: Physio- and stereo-chemical features of the sterol C3 group required for catalytic competence. |
2012 |
Arch. Biochem. Biophys. |
pmid:22446159
|
D'Agostino J et al. |
Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes. |
2012 |
J. Biol. Chem. |
pmid:22453923
|
Valdes VJ et al. |
CUP-1 is a novel protein involved in dietary cholesterol uptake in Caenorhabditis elegans. |
2012 |
PLoS ONE |
pmid:22479487
|
Abela IA et al. |
Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies. |
2012 |
PLoS Pathog. |
pmid:22496655
|
Zhang X and Zhang K |
Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes. |
2012 |
Biochem Res Int |
pmid:22506114
|