Dahl CE et al. |
Effects of cycloartenol and lanosterol on artificial and natural membranes. |
1980 |
Biochem. Biophys. Res. Commun. |
pmid:7356454
|
Nagai J et al. |
Effects of thiamine and pyridoxine on the content and composition of sterols in Saccharomyces carlsbergensis 4228. |
1974 |
Biochem. Biophys. Res. Commun. |
pmid:4418731
|
Alexander KT et al. |
A possible role for cytochrome P-450 during the biosynthesis of zymosterol from lanosterol by Saccharomyces cerevisiae. |
1974 |
Biochem. Biophys. Res. Commun. |
pmid:4609128
|
Pinkerton FD et al. |
Inhibitors of sterol synthesis. 14 alpha-ethyl-5 alpha-cholest-7-ene-3 beta,15 alpha-diol induces changes in the sterol composition and the morphology of CHO-K1 cells. |
1988 |
Biochem. Biophys. Res. Commun. |
pmid:3196343
|
Ruf A et al. |
The monotopic membrane protein human oxidosqualene cyclase is active as monomer. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14766201
|
Wiss O |
Influence of fasting and cholesterol feeding on the cholesterol synthesis in rats in vivo. |
1976 |
Biochem. Biophys. Res. Commun. |
pmid:1252233
|
Gibbons GF et al. |
Lanosterol 14alpha-demethylase. The metabolism of some potential intermediates by cell-free systems from rat liver. |
1976 |
Biochem. Biophys. Res. Commun. |
pmid:1267815
|
Karst F and Lacroute F |
Yeast mutant requiring only a sterol as growth supplement. |
1974 |
Biochem. Biophys. Res. Commun. |
pmid:4601817
|
Cabello-Hurtado F et al. |
Cloning and functional expression in yeast of a cDNA coding for an obtusifoliol 14alpha-demethylase (CYP51) in wheat. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9016788
|
Trocha PJ et al. |
Novel sterols in ergosterol deficient yeast mutants. |
1974 |
Biochem. Biophys. Res. Commun. |
pmid:4604829
|
Ohba M et al. |
Involvement of cytochrome P-450 and a cyanide-sensitive enzyme in different steps of lanosterol demethylation by yeast microsomes. |
1978 |
Biochem. Biophys. Res. Commun. |
pmid:369554
|
Taylor FR and Parks LW |
Adaptation of Saccharomyces cerevisiae to growth on cholesterol: selection of mutants defective in the formation of lanosterol. |
1980 |
Biochem. Biophys. Res. Commun. |
pmid:6998481
|
Buttke TM and Van Cleave S |
Adaptation of a cholesterol deficient human T cell line to growth with lanosterol. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8166689
|
Gollub EG et al. |
Yeast mutants requiring ergosterol as only lipid supplement. |
1974 |
Biochem. Biophys. Res. Commun. |
pmid:4363054
|
Seliskar M et al. |
Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18466759
|
Bard M et al. |
Characterization of a cytochrome P450 deficient mutant of Candida albicans. |
1987 |
Biochem. Biophys. Res. Commun. |
pmid:3307785
|
Revankar SG et al. |
Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474487
|
Jiang J et al. |
Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:22033405
|
Wiss O and Wiss V |
The degradation of labelled lanosterol by homogenate of rat liver: evidence for the formation of lithocholic acid from lanosterol without cholesterol as intermediate. |
1978 |
Biochem. Biophys. Res. Commun. |
pmid:708435
|
Aoyama Y and Yoshida Y |
Interaction of lanosterol to cytochrome P-450 purified from yeast microscomes: evidence for contribution of cytochrome P-450 to lanosterol metabolism. |
1978 |
Biochem. Biophys. Res. Commun. |
pmid:27189
|
Aoyama Y and Yoshida Y |
The 14alpha-demethylation of lanosterol by a reconstituted cytochrome P-450 system from yeast microsomes. |
1978 |
Biochem. Biophys. Res. Commun. |
pmid:105731
|
Kimura M et al. |
Protostadienol synthase from Aspergillus fumigatus: functional conversion into lanosterol synthase. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:19951700
|
Kushiro M et al. |
Obtusifoliol 14alpha-demethylase (CYP51) antisense Arabidopsis shows slow growth and long life. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11437378
|
Jackson CJ et al. |
Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12565899
|
Buttke TM and Bloch K |
Comparative responses of the yeast mutant strain GL7 to lanosterol, cycloartenol, and cyclolaudenol. |
1980 |
Biochem. Biophys. Res. Commun. |
pmid:6986865
|
M'Baya B and Karst F |
In vitro assay of squalene epoxidase of Saccharomyces cerevisiae. |
1987 |
Biochem. Biophys. Res. Commun. |
pmid:3307781
|
Emmons GT et al. |
20,25-Diazacholesterol, clofibric acid and 2,4-dichlorophenoxyacetic acid--all inducers of myotonia--perturb the post-lanosterol sector of sterol biosynthesis in cultured chick embryo fibroblasts. |
1980 |
Biochem. Biophys. Res. Commun. |
pmid:7437038
|
Yoshida Y et al. |
Sterol 14-demethylase P450 activity expressed in rat gonads: contribution to the formation of mammalian meiosis-activating sterol. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8687430
|
Ortiz de Montellano PR et al. |
Regulation of sterol biosynthesis and lysis of cultured hepatoma cells: inhibition of lanosterol demethylation by hydroxysterols. |
1979 |
Biochem. Biophys. Res. Commun. |
pmid:508352
|
Maitra US et al. |
Purification of a terminal oxygenase in demethylation of C-30 of lanosterol. |
1982 |
Biochem. Biophys. Res. Commun. |
pmid:6816234
|
Aoyama Y et al. |
Buthiobate: a potent inhibitor for yeast cytochrome P-450 catalyzing 14 alpha-demethylation of lanosterol. |
1983 |
Biochem. Biophys. Res. Commun. |
pmid:6414474
|
Aoyama Y and Yoshida Y |
Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24-methylene-24,25-dihydrolanosterol and 24,25-dihydrolanosterol. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1872829
|
Tabacik C et al. |
Post-HMG CoA reductase regulation of cholesterol biosynthesis in normal human lymphocytes : lanosten-3 betal-ol-32-al, a natural inhibitor. |
1981 |
Biochem. Biophys. Res. Commun. |
pmid:7306125
|
Aoyama Y and Yoshida Y |
Evidence for the contribution of a sterol 14-reductase to the 14 alpha-demethylation of lanosterol by yeast. |
1986 |
Biochem. Biophys. Res. Commun. |
pmid:2418830
|
Gaylor JL |
Membrane-bound enzymes of cholesterol synthesis from lanosterol. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11969204
|
Clayton R |
My years with Konrad, a memoir. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11969210
|
Nes WD et al. |
Control of fungal sterol C-24 transalkylation: importance to developmental regulation. |
1986 |
Biochem. Biophys. Res. Commun. |
pmid:3767970
|
Yoshida Y et al. |
Spectral properties of a novel cytochrome P-450 of a Saccharomyces cerevisiae mutant SG1. A cytochrome P-450 species having a nitrogenous ligand trans to thiolate. |
1985 |
Biochem. Biophys. Res. Commun. |
pmid:3884012
|
Zhang X and Zhang K |
Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes. |
2012 |
Biochem Res Int |
pmid:22506114
|
Wyder MA et al. |
Clearance in vivo of instilled [h]cholesterol from the rat lung. |
2010 |
Biochem Res Int |
pmid:21188079
|
Neil HA et al. |
Impact of atorvastatin and omega-3 ethyl esters 90 on plasma plant sterol concentrations and cholesterol synthesis in type 2 diabetes: a randomised placebo controlled factorial trial. |
2010 |
Atherosclerosis |
pmid:21036355
|
Relas H et al. |
Dietary squalene increases cholesterol synthesis measured with serum non-cholesterol sterols after a single oral dose in humans. |
2000 |
Atherosclerosis |
pmid:10998465
|
Fassbender K et al. |
Moderately elevated plant sterol levels are associated with reduced cardiovascular risk--the LASA study. |
2008 |
Atherosclerosis |
pmid:17137582
|
Ranganathan S et al. |
Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts. |
1982 |
Atherosclerosis |
pmid:7150392
|
Dull BJ et al. |
The modulating effect of an inhibitor of cholesterolgenesis present in bovine milk upon the synthesis of cholesterol, dolichol and ubiquinone. |
1983 |
Atherosclerosis |
pmid:6661267
|
Zhao LW et al. |
Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells. |
2014 |
Asian Pac. J. Cancer Prev. |
pmid:24815470
|
Rozenberg O et al. |
Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12615663
|
Burkhardt R et al. |
Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice. |
2011 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:21252064
|
Burgess B et al. |
Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice. |
2008 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:18599800
|
Kojima M et al. |
Altered gene expression of hepatic lanosterol 14alpha-demethylase (CYP51) in lead nitrate-treated rats. |
2002 |
Arch. Toxicol. |
pmid:12111004
|
Sun B et al. |
Two novel A-seco-rearranged lanostane triterpenoids from Abies sachalinensis. |
2008 |
Arch. Pharm. Res. |
pmid:19099219
|
Wang W et al. |
Design, synthesis, and antifungal activity of novel conformationally restricted triazole derivatives. |
2009 |
Arch. Pharm. (Weinheim) |
pmid:19899102
|
Clayton PT |
Disorders of cholesterol biosynthesis. |
1998 |
Arch. Dis. Child. |
pmid:9579167
|
Johnson RC and Shah SN |
Microsomal synthesis of cholesterol from squalene, Lanosterol, and desmosterol. Evidence for the presence of two noncatalytic activator proteins in the 105,000 g supernatant fraction from brain, heart, and kidney. |
1974 |
Arch. Biochem. Biophys. |
pmid:4460877
|
Lepesheva GI et al. |
Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET. |
2007 |
Arch. Biochem. Biophys. |
pmid:17585868
|
Fryberg M et al. |
Sterol biosynthesis in antibiotic-resistant yeast: nystatin. |
1974 |
Arch. Biochem. Biophys. |
pmid:4597559
|
Kolesnikova MD et al. |
Lanosterol biosynthesis in plants. |
2006 |
Arch. Biochem. Biophys. |
pmid:16445886
|
Fryberg M et al. |
Sterol biosynthesis in antibiotic sensitive and resistant Candida. |
1976 |
Arch. Biochem. Biophys. |
pmid:769695
|
Li L and Porter TD |
Hepatic cytochrome P450 reductase-null mice reveal a second microsomal reductase for squalene monooxygenase. |
2007 |
Arch. Biochem. Biophys. |
pmid:17374357
|
Debeljak N et al. |
Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51. |
2003 |
Arch. Biochem. Biophys. |
pmid:12464255
|
Howard AL et al. |
Sterol C24-methyltransferase: Physio- and stereo-chemical features of the sterol C3 group required for catalytic competence. |
2012 |
Arch. Biochem. Biophys. |
pmid:22446159
|
Leonard DA et al. |
Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 3 beta-hydroxy-lanost-8-en-32-al, an intermediate in the conversion of lanosterol to cholesterol. |
1994 |
Arch. Biochem. Biophys. |
pmid:8161198
|
STOKES WM |
The separation of the compounds of the lanosterol group present in "isocholesterol" by chromatography of the p-iodobenzoates-I 131 and benzoates. |
1957 |
Arch. Biochem. Biophys. |
pmid:13425621
|
Anderson JA et al. |
15-substituted lanosterols: post-transcriptional suppressors of 3-hydroxy-3-methylglutaryl coenzyme A reductase. |
1995 |
Arch. Biochem. Biophys. |
pmid:7840615
|
Park HG et al. |
Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans. |
2011 |
Arch. Biochem. Biophys. |
pmid:21315684
|
Nes WD et al. |
Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. |
2009 |
Arch. Biochem. Biophys. |
pmid:19014901
|
Pikuleva I and Javitt NB |
Novel sterols synthesized via the CYP27A1 metabolic pathway. |
2003 |
Arch. Biochem. Biophys. |
pmid:14622972
|
Song MK and Dempsey ME |
Requirement for a major soluble protein in the conversion of lanosterol to cholesterol by membrane-bound enzymes. |
1981 |
Arch. Biochem. Biophys. |
pmid:7305386
|
Ness GC et al. |
Regulation of hepatic lanosterol 14 alpha-demethylase gene expression by dietary cholesterol and cholesterol-lowering agents. |
2001 |
Arch. Biochem. Biophys. |
pmid:11697861
|
Field RB and Holmlund CE |
Isolation of 2,3;22,23-dioxidosqualene and 24,25-oxidolanosterol from yeast. |
1977 |
Arch. Biochem. Biophys. |
pmid:327938
|
Nes WD et al. |
Metabolism of 24(R,S),25-epiminolanosterol to 25-aminolanosterol and lanosterol by Gibberella fujikuroi. |
1989 |
Arch. Biochem. Biophys. |
pmid:2751307
|
Rippon JW |
A new era in antimycotic agents. |
1986 |
Arch Dermatol |
pmid:3006601
|
Shi L et al. |
Current progress in the study on biosynthesis and regulation of ganoderic acids. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:20859739
|
Xu JW et al. |
Production of individual ganoderic acids and expression of biosynthetic genes in liquid static and shaking cultures of Ganoderma lucidum. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:19578843
|
Xu JW et al. |
Biotechnological production and application of ganoderic acids. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:20437236
|
Liang CX et al. |
Enhanced biosynthetic gene expressions and production of ganoderic acids in static liquid culture of Ganoderma lucidum under phenobarbital induction. |
2010 |
Appl. Microbiol. Biotechnol. |
pmid:20077112
|
Zhao Z et al. |
Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol. |
2011 |
Appl. Microbiol. Biotechnol. |
pmid:20809073
|
Price CL et al. |
Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase. |
2015 |
Appl. Environ. Microbiol. |
pmid:25746994
|
Parker JE et al. |
Mechanism of binding of prothioconazole to Mycosphaerella graminicola CYP51 differs from that of other azole antifungals. |
2011 |
Appl. Environ. Microbiol. |
pmid:21169436
|
Hajjaj H et al. |
Effect of 26-oxygenosterols from Ganoderma lucidum and their activity as cholesterol synthesis inhibitors. |
2005 |
Appl. Environ. Microbiol. |
pmid:16000773
|
Parker JE et al. |
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. |
2008 |
Antimicrob. Agents Chemother. |
pmid:18694951
|
Van den Bossche H et al. |
In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis. |
1980 |
Antimicrob. Agents Chemother. |
pmid:6250469
|
Warrilow AG et al. |
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme. |
2016 |
Antimicrob. Agents Chemother. |
pmid:27161631
|
Sagatova AA et al. |
Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase. |
2015 |
Antimicrob. Agents Chemother. |
pmid:26055382
|
Buurman ET et al. |
Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. |
2005 |
Antimicrob. Agents Chemother. |
pmid:15917573
|
Kaneshiro ES et al. |
Inhibitors of sterol biosynthesis and amphotericin B reduce the viability of pneumocystis carinii f. sp. carinii. |
2000 |
Antimicrob. Agents Chemother. |
pmid:10817720
|
Warrilow AG et al. |
S279 point mutations in Candida albicans Sterol 14-α demethylase (CYP51) reduce in vitro inhibition by fluconazole. |
2012 |
Antimicrob. Agents Chemother. |
pmid:22252802
|
Warrilow AG et al. |
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens. |
2013 |
Antimicrob. Agents Chemother. |
pmid:23274672
|
Vanden Bossche H et al. |
Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans. |
1993 |
Antimicrob. Agents Chemother. |
pmid:8257130
|
Warrilow AG et al. |
Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B. |
2010 |
Antimicrob. Agents Chemother. |
pmid:20660663
|
Sud IJ and Feingold DS |
Heterogeneity of action of mechanisms among antimycotic imidazoles. |
1981 |
Antimicrob. Agents Chemother. |
pmid:6269485
|
Nomura M et al. |
Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis. |
2008 Sep-Oct |
Anticancer Res. |
pmid:19035296
|
Schroepfer GJ |
Sterol biosynthesis. |
1982 |
Annu. Rev. Biochem. |
pmid:6810750
|
Ruzicka L |
In the borderland between bioorganic chemistry and biochemistry. |
1973 |
Annu. Rev. Biochem. |
pmid:4600996
|
Cooper AB et al. |
Synthesis and antifungal properties of 14-aminomethyl-substituted lanosterol derivatives. |
1988 |
Ann. N. Y. Acad. Sci. |
pmid:3214062
|
Krisans SK |
Cell compartmentalization of cholesterol biosynthesis. |
1996 |
Ann. N. Y. Acad. Sci. |
pmid:8993542
|
Gaylor JL and Delwiche CV |
Investigation of the multienzymic system of microsomal cholesterol biosynthesis. |
1973 |
Ann. N. Y. Acad. Sci. |
pmid:4532473
|
Stocker A |
Molecular mechanisms of vitamin E transport. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15753133
|
Barrett-Bee K et al. |
Biochemical studies with a novel antifungal agent, ICI 195,739. |
1988 |
Ann. N. Y. Acad. Sci. |
pmid:3063170
|
Marco-Jiménez F et al. |
Effects of lanosterol on in vitro maturation of porcine oocytes. |
2010 |
Anim. Reprod. Sci. |
pmid:19473792
|