Zhu J et al. |
Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway. |
2018 |
Chem. Biol. Interact. |
pmid:29852127
|
Teng Y et al. |
Hebecarposides A-K, antiproliferative lanostane-type triterpene glycosides from the leaves of Lyonia ovalifolia var. hebecarpa. |
2018 |
Phytochemistry |
pmid:29660562
|
Freitas HF et al. |
Cloning, expression, purification and spectrophotometric analysis of lanosterol 14-alpha demethylase from Leishmania braziliensis (LbCYP51). |
2018 |
Mol. Biol. Rep. |
pmid:29363024
|
Lu DL et al. |
Reproducibility of serum oxysterols and lanosterol among postmenopausal women: Results from EPIC-Heidelberg. |
2018 |
Clin. Biochem. |
pmid:29108727
|
Chen XQ et al. |
Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. |
2018 |
Phytochemistry |
pmid:29490285
|
Dai J et al. |
Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum. |
2017 |
Oncotarget |
pmid:28099150
|
Sidjui LS et al. |
Bioactive Seco-Lanostane-Type Triterpenoids from the Roots of Leplaea mayombensis. |
2017 |
J. Nat. Prod. |
pmid:28945373
|
Lv L et al. |
Quantitation of lanosterol in the vitreous humor of rabbits after ocular administration of lanosterol/thermogel formulation by ultra high performance liquid chromatography-tandem mass spectrometry with the electrospray ionization mode. |
2017 |
J Chromatogr A |
pmid:28888677
|
Vidal-Limon AM et al. |
Molecular Dynamics and Virtual Screening Analysis of Lanosterol Derivatives from Ganoderma Medicinal Mushrooms (Agaricomycetes) as Selective Ligands of Human Androgen Receptor. |
2017 |
Int J Med Mushrooms |
pmid:29199581
|
Park JW et al. |
Nitric oxide stimulates cellular degradation of human CYP51A1, the highly conserved lanosterol 14α-demethylase. |
2017 |
Biochem. J. |
pmid:28830911
|
Lin CH et al. |
Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice. |
2017 |
Int J Mol Sci |
pmid:29099085
|
Huang SZ et al. |
Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. |
2017 |
Phytochemistry |
pmid:28800421
|
Kidane ME et al. |
Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug design. |
2017 |
J. Lipid Res. |
pmid:29042405
|
Isaka M et al. |
Antitubercular Activity of Mycelium-Associated Ganoderma Lanostanoids. |
2017 |
J. Nat. Prod. |
pmid:28504879
|
Yusakul G et al. |
Bacterial Expression of a Single-Chain Variable Fragment (scFv) Antibody against Ganoderic Acid A: A Cost-Effective Approach for Quantitative Analysis Using the scFv-Based Enzyme-Linked Immunosorbent Assay. |
2017 |
Biol. Pharm. Bull. |
pmid:28966249
|
Cao FR et al. |
Plasma and brain pharmacokinetics of ganoderic acid A in rats determined by a developed UFLC-MS/MS method. |
2017 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:28346885
|
Wang X et al. |
Ganoderic acid A inhibits proliferation and invasion, and promotes apoptosis in human hepatocellular carcinoma cells. |
2017 |
Mol Med Rep |
pmid:28731159
|
Wang J et al. |
Eburicoic acid from Laetiporus sulphureus (Bull.:Fr.) Murrill attenuates inflammatory responses through inhibiting LPS-induced activation of PI3K/Akt/mTOR/NF-κB pathways in RAW264.7 cells. |
2017 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:28577049
|
Zhang DH et al. |
Overexpression of the homologous lanosterol synthase gene in ganoderic acid biosynthesis in Ganoderma lingzhi. |
2017 |
Phytochemistry |
pmid:27894599
|
Zhang G et al. |
Ethylene promotes mycelial growth and ganoderic acid biosynthesis in Ganoderma lucidum. |
2017 |
Biotechnol. Lett. |
pmid:27771819
|
Katja DG et al. |
Cytototoxic constituents from the bark of Chisocheton cumingianus (Meliaceae). |
2017 |
J Asian Nat Prod Res |
pmid:27329305
|
Gao Y et al. |
In Vitro and In Vivo Activity of Fomitopsis Pinicola (Sw. Ex Fr.) Karst Chloroform (Fpkc) Extract Against S180 Tumor Cells. |
2017 |
Cell. Physiol. Biochem. |
pmid:29241162
|
Wang XL et al. |
Efficient Accumulation and In Vitro Antitumor Activities of Triterpene Acids from Submerged Batch--Cultured Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes). |
2017 |
Int J Med Mushrooms |
pmid:28845771
|
Araldi E et al. |
Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages. |
2017 |
Cell Rep |
pmid:28658622
|
Tallman KA et al. |
Probes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor. |
2017 |
Redox Biol |
pmid:28258022
|
Kim JW et al. |
Effects of Ganodermanondiol, a New Melanogenesis Inhibitor from the Medicinal Mushroom Ganoderma lucidum. |
2016 |
Int J Mol Sci |
pmid:27801787
|
Wang XL et al. |
Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi. |
2016 |
Molecules |
pmid:27775633
|
Venkatesh R et al. |
Comment to: Effect of lanosterol on human nuclei. |
2016 |
Indian J Ophthalmol |
pmid:27488164
|
Hargrove TY et al. |
Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design. |
2016 |
J. Lipid Res. |
pmid:27313059
|
Kuo YH et al. |
Dehydroeburicoic Acid from Antrodia camphorata Prevents the Diabetic and Dyslipidemic State via Modulation of Glucose Transporter 4, Peroxisome Proliferator-Activated Receptor α Expression and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice. |
2016 |
Int J Mol Sci |
pmid:27271603
|
Warrilow AG et al. |
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme. |
2016 |
Antimicrob. Agents Chemother. |
pmid:27161631
|
Stäubert C et al. |
Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells. |
2016 |
Med. Oncol. |
pmid:26698156
|
Schrack S et al. |
Oxysterols in cosmetics-Determination by planar solid phase extraction and gas chromatography-mass spectrometry. |
2016 |
J Chromatogr A |
pmid:28314390
|
Suarez-Medellin J et al. |
In Silico Analysis of Lanostanoids Characterized in Ganoderma Mushrooms (Agaricomycetes) as Potential Ligands of the Vitamin D Receptor. |
2016 |
Int J Med Mushrooms |
pmid:28008815
|
Lai KH et al. |
Cytotoxic Lanostanoids from Poria cocos. |
2016 |
J. Nat. Prod. |
pmid:27808511
|
Hongthong S et al. |
Cytotoxic lanostanes from fruits of Garcinia wallichii Choisy (Guttiferae). |
2016 |
Bioorg. Med. Chem. Lett. |
pmid:27793565
|
Hu ZX et al. |
Rearranged 6/6/5/6-Fused Triterpenoid Acids from the Stems of Kadsura coccinea. |
2016 |
J. Nat. Prod. |
pmid:27704807
|
Gill BS et al. |
Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. |
2016 |
Mol. Biol. Rep. |
pmid:27640015
|
Sakamoto S et al. |
Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma lingzhi. |
2016 |
Fitoterapia |
pmid:27575328
|
Kwon J et al. |
Lanostane Triterpenes Isolated from Antrodia heteromorpha and Their Inhibitory Effects on RANKL-Induced Osteoclastogenesis. |
2016 |
J. Nat. Prod. |
pmid:27266877
|
Han J et al. |
Officimalonic acids A-H, lanostane triterpenes from the fruiting bodies of Fomes officinalis. |
2016 |
Phytochemistry |
pmid:27216472
|
Sakamoto S et al. |
Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay. |
2016 |
Planta Med. |
pmid:27093250
|
Li HJ et al. |
Enhancement of ganoderic acid production by constitutively expressing Vitreoscilla hemoglobin gene in Ganoderma lucidum. |
2016 |
J. Biotechnol. |
pmid:27080449
|
Amen YM et al. |
Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells. |
2016 |
J Nat Med |
pmid:26899240
|
Isaka M et al. |
Antitubercular Lanostane Triterpenes from Cultures of the Basidiomycete Ganoderma sp. BCC 16642. |
2016 |
J. Nat. Prod. |
pmid:26716912
|
Qiu J et al. |
Neuroprotective and antioxidant lanostanoid triterpenes from the fruiting bodies of Ganoderma atrum. |
2016 |
Fitoterapia |
pmid:26709153
|
Lee S et al. |
Lanosterol influences cytoplasmic maturation of pig oocytes in vitro and improves preimplantation development of cloned embryos. |
2016 |
Theriogenology |
pmid:26494176
|
OuYang Q et al. |
Transcriptional profiling analysis of Penicillium digitatum, the causal agent of citrus green mold, unravels an inhibited ergosterol biosynthesis pathway in response to citral. |
2016 |
BMC Genomics |
pmid:27514516
|
Novack GD |
Eyes on New Product Development. |
2016 |
J Ocul Pharmacol Ther |
pmid:27058691
|
AÄimoviÄ J et al. |
Cytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis. |
2016 |
Sci Rep |
pmid:27334049
|
Chen N et al. |
Biosynthetic Mechanism of Lanosterol: Cyclization. |
2015 |
Angew. Chem. Int. Ed. Engl. |
pmid:26069216
|
Das A et al. |
A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway. |
2015 |
Tumour Biol. |
pmid:25864108
|
Shanmugam PM et al. |
Effect of lanosterol on human cataract nucleus. |
2015 |
Indian J Ophthalmol |
pmid:26862091
|
Mendiara I et al. |
Online solid-phase extraction-liquid chromatography-mass spectrometry to determine free sterols in human serum. |
2015 |
Talanta |
pmid:25476366
|
Mosa RA et al. |
In vivo antihyperglycemic activity of a lanosteryl triterpene from Protorhus longifolia. |
2015 |
Molecules |
pmid:26205060
|
Sagatova AA et al. |
Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase. |
2015 |
Antimicrob. Agents Chemother. |
pmid:26055382
|
Price CL et al. |
Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase. |
2015 |
Appl. Environ. Microbiol. |
pmid:25746994
|
Zhang SS et al. |
Three new lanostanoids from the mushroom Ganoderma tropicum. |
2015 |
Molecules |
pmid:25690289
|
Dutra RC et al. |
The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε. |
2015 |
Neuroscience |
pmid:26143011
|
Zhao XR et al. |
Inhibitory Effects of Highly Oxygenated Lanostane Derivatives from the Fungus Ganoderma lucidum on P-Glycoprotein and α-Glucosidase. |
2015 |
J. Nat. Prod. |
pmid:26222905
|
Wang J et al. |
Protective Effect of Eburicoic Acid of the Chicken of the Woods Mushroom, Laetiporus sulphureus (Higher Basidiomycetes), Against Gastric Ulcers in Mice. |
2015 |
Int J Med Mushrooms |
pmid:26559696
|
Quinlan RA |
DRUG DISCOVERY. A new dawn for cataracts. |
2015 |
Science |
pmid:26542559
|
Kuo YH et al. |
Antidiabetic and Antihyperlipidemic Properties of a Triterpenoid Compound, Dehydroeburicoic Acid, from Antrodia camphorata in Vitro and in Streptozotocin-Induced Mice. |
2015 |
J. Agric. Food Chem. |
pmid:26503742
|
Gundersen BB |
Clearing cataracts without surgery. |
2015 |
Lab Anim (NY) |
pmid:26398599
|
Hu ZX et al. |
Kadcoccinones A-F, New Biogenetically Related Lanostane-Type Triterpenoids with Diverse Skeletons from Kadsura coccinea. |
2015 |
Org. Lett. |
pmid:26348535
|
Ruan W et al. |
Distinct Responses of Cytotoxic Ganoderma lucidum Triterpenoids in Human Carcinoma Cells. |
2015 |
Phytother Res |
pmid:26292672
|
Zhao L et al. |
Lanosterol reverses protein aggregation in cataracts. |
2015 |
Nature |
pmid:26200341
|
Hejtmancik JF |
Ophthalmology: Cataracts dissolved. |
2015 |
Nature |
pmid:26200338
|
Li G et al. |
Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
2015 |
J. Nat. Prod. |
pmid:26186257
|
Feng W and Yang JS |
A new drimane sesquiterpenoid and a new triterpene lactone from fungus of Fomes officinalis. |
2015 |
J Asian Nat Prod Res |
pmid:26123159
|
Wang GW et al. |
Lanostane-type triterpenoids from Abies faxoniana and their DNA topoisomerase inhibitory activities. |
2015 |
Phytochemistry |
pmid:25986863
|
Kürten C et al. |
Overexpression of functional human oxidosqualene cyclase in Escherichia coli. |
2015 |
Protein Expr. Purif. |
pmid:25962741
|
Yin X et al. |
Four lanostane-type triterpenes from the fruiting bodies of mushroom Laetiporus sulphureus var. miniatus. |
2015 |
J Asian Nat Prod Res |
pmid:25916960
|
O'Keeffe R et al. |
Synthesis of novel 24-amino-25,26,27-trinorlanost-8-enes: cytotoxic and apoptotic potential in U937 cells. |
2015 |
Bioorg. Med. Chem. |
pmid:25800433
|
Liu JY et al. |
Mechanisms of azole resistance in Candida albicans clinical isolates from Shanghai, China. |
2015 |
Res. Microbiol. |
pmid:25748216
|
Leoni V and Caccia C |
The impairment of cholesterol metabolism in Huntington disease. |
2015 |
Biochim. Biophys. Acta |
pmid:25596342
|
Zhang SS et al. |
Lanostanoids with acetylcholinesterase inhibitory activity from the mushroom Haddowia longipes. |
2015 |
Phytochemistry |
pmid:25577284
|
Jamila N et al. |
Molecular docking studies and in vitro cholinesterase enzyme inhibitory activities of chemical constituents of Garcinia hombroniana. |
2015 |
Nat. Prod. Res. |
pmid:25219673
|
Chen CL et al. |
Euphol from Euphorbia tirucalli Negatively Modulates TGF-β Responsiveness via TGF-β Receptor Segregation inside Membrane Rafts. |
2015 |
PLoS ONE |
pmid:26448474
|
Ren A et al. |
Transcript and metabolite alterations increase ganoderic acid content in Ganoderma lucidum using acetic acid as an inducer. |
2014 |
Biotechnol. Lett. |
pmid:25216642
|
Chiba T et al. |
Fomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. |
2014 |
PLoS ONE |
pmid:25551765
|
Machaba KE et al. |
In vivo anti-hyperlipidemic activity of the triterpene from the stem bark of Protorhus longifolia (Benrh) Engl. |
2014 |
Lipids Health Dis |
pmid:25127687
|
Zhao LW et al. |
Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells. |
2014 |
Asian Pac. J. Cancer Prev. |
pmid:24815470
|
Jennings GK et al. |
Spin equilibrium and Oâ‚‚-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine-threonine dyad. |
2014 |
J. Inorg. Biochem. |
pmid:24793591
|
Munhoz AC et al. |
Chemical and pharmacological investigation of the stem bark of Synadenium grantii. |
2014 |
Planta Med. |
pmid:24687740
|
Peng XR et al. |
Hepatoprotective effects of triterpenoids from Ganoderma cochlear. |
2014 |
J. Nat. Prod. |
pmid:24559087
|
Liu C et al. |
Chemical constituents from Inonotus obliquus and their biological activities. |
2014 |
J. Nat. Prod. |
pmid:24359303
|
Ying YM et al. |
Terpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquus. |
2014 |
Phytochemistry |
pmid:25446238
|
Mosa RA et al. |
In vitro antihyperlipidemic potential of triterpenes from stem bark of Protorhus longifolia. |
2014 |
Planta Med. |
pmid:25389058
|
Ruan W et al. |
Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growth. |
2014 |
Nat. Prod. Res. |
pmid:25032738
|
Gas-Pascual E et al. |
Plant oxidosqualene metabolism: cycloartenol synthase-dependent sterol biosynthesis in Nicotiana benthamiana. |
2014 |
PLoS ONE |
pmid:25343375
|
Marco-Jiménez F et al. |
Effect of lanosterol on the in vitro maturation in semi-defined culture system of prepubertal ewe oocytes. |
2014 |
Zygote |
pmid:21838962
|
Baila-Rueda L et al. |
Bile acid synthesis precursors in familial combined hyperlipidemia: the oxysterols 24S-hydroxycholesterol and 27-hydroxycholesterol. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24406166
|
Yajima Y et al. |
Production of Ginkgo leaf-shaped basidiocarps of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes), containing high levels of α- and β-D-glucan and ganoderic acid A. |
2013 |
Int J Med Mushrooms |
pmid:23557369
|
Lin KW et al. |
Xanthine oxidase inhibitory lanostanoids from Ganoderma tsugae. |
2013 |
Fitoterapia |
pmid:23769935
|
Kolesnikova SA et al. |
Isolation, structures, and biological activities of triterpenoids from a Penares sp. marine sponge. |
2013 |
J. Nat. Prod. |
pmid:23978047
|
Patkar P et al. |
C-24-methylation of 26-fluorocycloartenols by recombinant sterol C-24-methyltransferase from soybean: evidence for channel switching and its phylogenetic implications. |
2013 |
Biochem. J. |
pmid:23984880
|
Zhang Y et al. |
[Dynamic accumulation of three main triterpenic acids in submerged cultivation mycelium of Poria cocos]. |
2013 |
Zhongguo Zhong Yao Za Zhi |
pmid:23944068
|
Huang GJ et al. |
Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. |
2013 |
Food Chem |
pmid:23871054
|
Ha do T et al. |
In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress. |
2013 |
J Ethnopharmacol |
pmid:24140584
|