Fan J et al. |
Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. |
2013 |
New Phytol. |
pmid:23442154
|
Madoui MA et al. |
Sterol metabolism in the oomycete Aphanomyces euteiches, a legume root pathogen. |
2009 |
New Phytol. |
pmid:19496952
|
Modica S et al. |
Deciphering the nuclear bile acid receptor FXR paradigm. |
2010 |
Nucl Recept Signal |
pmid:21383957
|
Sharman JL et al. |
IUPHAR-DB: updated database content and new features. |
2013 |
Nucleic Acids Res. |
pmid:23087376
|
Hu J et al. |
Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones. |
2010 |
Nutr Metab (Lond) |
pmid:20515451
|
Chung MJ et al. |
Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells. |
2010 |
Nutr Res Pract |
pmid:20607061
|
Dai J et al. |
Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum. |
2017 |
Oncotarget |
pmid:28099150
|
Skinner C and Miraldi Utz V |
Pharmacological approaches to restoring lens transparency: Real world applications. |
|
Ophthalmic Genet. |
pmid:27648776
|
Matsuda SP et al. |
Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies. |
2006 |
Org. Biomol. Chem. |
pmid:16446812
|
Winne JM et al. |
Nonenzymic polycyclization of analogues of oxidosqualene with a preformed C-ring. |
2008 |
Org. Biomol. Chem. |
pmid:18480904
|
Wu TK et al. |
Mutation of isoleucine 705 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae affects lanosterol's C/D-ring cyclization and 17α/β-exocyclic side chain stereochemistry. |
2011 |
Org. Biomol. Chem. |
pmid:21157613
|
Yang XW et al. |
Abiesatrines A-J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr. |
2010 |
Org. Biomol. Chem. |
pmid:20372737
|
Hess BA |
Formation of the C ring in the lanosterol biosynthesis from squalene. |
2003 |
Org. Lett. |
pmid:12529131
|
Wu TK et al. |
Importance of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase tyrosine 707 residue for chair-boat bicyclic ring formation and deprotonation reactions. |
2008 |
Org. Lett. |
pmid:18842050
|
Wu TK et al. |
Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions. |
2006 |
Org. Lett. |
pmid:16562881
|
Meyer MM et al. |
Directed evolution to generate cycloartenol synthase mutants that produce lanosterol. |
2002 |
Org. Lett. |
pmid:11950371
|
Joubert BM et al. |
Trypanosome and animal lanosterol synthases use different catalytic motifs. |
2001 |
Org. Lett. |
pmid:11405754
|
Segura MJ et al. |
Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis. |
2002 |
Org. Lett. |
pmid:12465912
|
Matsuda SP et al. |
Steric bulk at cycloartenol synthase position 481 influences cyclization and deprotonation. |
2000 |
Org. Lett. |
pmid:10930258
|
Hu ZX et al. |
Kadcoccinones A-F, New Biogenetically Related Lanostane-Type Triterpenoids with Diverse Skeletons from Kadsura coccinea. |
2015 |
Org. Lett. |
pmid:26348535
|
Ito R et al. |
Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases. |
2011 |
Org. Lett. |
pmid:21526825
|
Liu YT et al. |
Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase. |
2012 |
Org. Lett. |
pmid:23043506
|
Kaneshiro ES |
Biochemical research elucidating metabolic pathways in Pneumocystis. |
2010 |
Parasite |
pmid:21275234
|
Adachi M et al. |
Abnormal steroidogenesis in three patients with Antley-Bixler syndrome: apparent decreased activity of 17alpha-hydroxylase, 17,20-lyase and 21-hydroxylase. |
2004 |
Pediatr Int |
pmid:15491389
|
Chandrasekar SB et al. |
Phytopharmacology of Ficus religiosa. |
2010 |
Pharmacogn Rev |
pmid:22228961
|
Chen NH et al. |
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. |
2010 Jan-Feb |
Pharmacol Rep |
pmid:20360625
|
Du D et al. |
Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection. |
2011 Sep-Oct |
Phytochem Anal |
pmid:21433158
|
Ori K et al. |
Lanosterol and tetranorlanosterol glycosides from the bulbs of Muscari paradoxum. |
2003 |
Phytochemistry |
pmid:14629999
|
Mimaki Y et al. |
Lanosterol and 27-norlanosterol oligosaccharides from the bulbs of Chionodoxa gigantea. |
1993 |
Phytochemistry |
pmid:7764152
|
Haba H et al. |
Diterpenoids and triterpenoids from Euphorbia guyoniana. |
2007 |
Phytochemistry |
pmid:17337022
|
David Nes W and Nichols SD |
Phytosterol biosynthesis pathway in Mortierella alpina. |
2006 |
Phytochemistry |
pmid:16647729
|
Teng Y et al. |
Hebecarposides A-K, antiproliferative lanostane-type triterpene glycosides from the leaves of Lyonia ovalifolia var. hebecarpa. |
2018 |
Phytochemistry |
pmid:29660562
|
Majumder PL et al. |
Triterpenoids from the orchids Agrostophyllum brevipes and Agrostophyllum callosum. |
2003 |
Phytochemistry |
pmid:12560031
|
Huang SZ et al. |
Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. |
2017 |
Phytochemistry |
pmid:28800421
|
Zhang DH et al. |
Overexpression of the homologous lanosterol synthase gene in ganoderic acid biosynthesis in Ganoderma lingzhi. |
2017 |
Phytochemistry |
pmid:27894599
|
Han J et al. |
Officimalonic acids A-H, lanostane triterpenes from the fruiting bodies of Fomes officinalis. |
2016 |
Phytochemistry |
pmid:27216472
|
Wang GW et al. |
Lanostane-type triterpenoids from Abies faxoniana and their DNA topoisomerase inhibitory activities. |
2015 |
Phytochemistry |
pmid:25986863
|
Zhang SS et al. |
Lanostanoids with acetylcholinesterase inhibitory activity from the mushroom Haddowia longipes. |
2015 |
Phytochemistry |
pmid:25577284
|
Ying YM et al. |
Terpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquus. |
2014 |
Phytochemistry |
pmid:25446238
|
Handa N et al. |
An unusual lanostane-type triterpenoid, spiroinonotsuoxodiol, and other triterpenoids from Inonotus obliquus. |
2010 |
Phytochemistry |
pmid:20691456
|
Nguyen HD et al. |
Friedolanostane, friedocycloartane and benzophenone constituents of the bark and leaves of Garcinia benthami. |
2011 |
Phytochemistry |
pmid:21168174
|
Chen XQ et al. |
Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. |
2018 |
Phytochemistry |
pmid:29490285
|
Elfita E et al. |
Antiplasmodial and other constituents from four Indonesian Garcinia spp. |
2009 |
Phytochemistry |
pmid:19481231
|
Du YC et al. |
Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models. |
2012 |
Phytomedicine |
pmid:22516893
|
Fernandez-Arche A et al. |
Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex. |
2010 |
Phytomedicine |
pmid:19577446
|
Chen NH and Zhong JJ |
p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells. |
2011 |
Phytomedicine |
pmid:21353507
|
Ruan W et al. |
Distinct Responses of Cytotoxic Ganoderma lucidum Triterpenoids in Human Carcinoma Cells. |
2015 |
Phytother Res |
pmid:26292672
|
Suzuki M et al. |
Lanosterol synthase in dicotyledonous plants. |
2006 |
Plant Cell Physiol. |
pmid:16531458
|
Sawai S et al. |
Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes. |
2006 |
Plant Cell Physiol. |
pmid:16531457
|
Vanmierlo T et al. |
Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. |
2011 |
Plant Foods Hum Nutr |
pmid:21431910
|
Husselstein-Muller T et al. |
Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. |
2001 |
Plant Mol. Biol. |
pmid:11247608
|
Chen Q et al. |
Biosynthesis of phytosterol esters: identification of a sterol o-acyltransferase in Arabidopsis. |
2007 |
Plant Physiol. |
pmid:17885082
|
O'Brien M et al. |
Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity. |
2005 |
Plant Physiol. |
pmid:16169959
|
Wang Z et al. |
Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids. |
2011 |
Plant Physiol. |
pmid:21059824
|
Carland F et al. |
The sterol methyltransferases SMT1, SMT2, and SMT3 influence Arabidopsis development through nonbrassinosteroid products. |
2010 |
Plant Physiol. |
pmid:20421456
|
Koyama K et al. |
Antinociceptive components of Ganoderma lucidum. |
1997 |
Planta Med. |
pmid:9225603
|
Min BS et al. |
Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. |
2001 |
Planta Med. |
pmid:11745016
|
Yao X et al. |
Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin. |
2012 |
Planta Med. |
pmid:22961117
|
Wang N et al. |
Five new 3,4-seco-lanostane-type triterpenoids with antiproliferative activity in human leukemia cells isolated from the roots of Kadsura coccinea. |
2012 |
Planta Med. |
pmid:22948612
|
Sakamoto S et al. |
Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay. |
2016 |
Planta Med. |
pmid:27093250
|
Ha TB et al. |
New lanostanoids from Ganoderma lucidum that induce NAD(P)H:quinone oxidoreductase in cultured hepalcic7 murine hepatoma cells. |
2000 |
Planta Med. |
pmid:11105584
|
Munhoz AC et al. |
Chemical and pharmacological investigation of the stem bark of Synadenium grantii. |
2014 |
Planta Med. |
pmid:24687740
|
Mosa RA et al. |
In vitro antihyperlipidemic potential of triterpenes from stem bark of Protorhus longifolia. |
2014 |
Planta Med. |
pmid:25389058
|
Wang GJ et al. |
Lanostanes from Phellinus igniarius and their iNOS inhibitory activities. |
2009 |
Planta Med. |
pmid:19557671
|
Liu XT et al. |
Antibacterial compounds from mushrooms I: a lanostane-type triterpene and prenylphenol derivatives from Jahnoporus hirtus and Albatrellus flettii and their activities against Bacillus cereus and Enterococcus faecalis. |
2010 |
Planta Med. |
pmid:19644795
|
Liu J et al. |
Ganoderic acids from Ganoderma lucidum: inhibitory activity of osteoclastic differentiation and structural criteria. |
2010 |
Planta Med. |
pmid:19670160
|
Singh GB et al. |
Hypotensive activity of 8,24-euphadien-3 beta-ol (euphol). |
1989 |
Planta Med. |
pmid:2616667
|
Fatmawati S et al. |
Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. |
2010 |
Planta Med. |
pmid:20379959
|
Iskar M et al. |
Drug-induced regulation of target expression. |
2010 |
PLoS Comput. Biol. |
pmid:20838579
|
Thomas JH |
Rapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebrates. |
2007 |
PLoS Genet. |
pmid:17500592
|
Stottmann RW et al. |
Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo. |
2011 |
PLoS Genet. |
pmid:21912524
|
Selmecki AM et al. |
Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. |
2009 |
PLoS Genet. |
pmid:19876375
|
Ma LJ et al. |
Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication. |
2009 |
PLoS Genet. |
pmid:19578406
|
Chen CK et al. |
Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit. |
2009 |
PLoS Negl Trop Dis |
pmid:19190730
|
Chen CK et al. |
Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. |
2010 |
PLoS Negl Trop Dis |
pmid:20386598
|
Alvarez-Vasquez F et al. |
Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae. |
2011 |
PLoS ONE |
pmid:22194828
|
Jeschke MG et al. |
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes. |
2012 |
PLoS ONE |
pmid:22606232
|
Brumfield KM et al. |
Functional characterization of the Chlamydomonas reinhardtii ERG3 ortholog, a gene involved in the biosynthesis of ergosterol. |
2010 |
PLoS ONE |
pmid:20084111
|
Chiba T et al. |
Fomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. |
2014 |
PLoS ONE |
pmid:25551765
|
Alvarez-Rueda N et al. |
Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance. |
2011 |
PLoS ONE |
pmid:21698128
|
Cushion MT et al. |
Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. |
2007 |
PLoS ONE |
pmid:17487271
|
Vinci G et al. |
Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. |
2008 |
PLoS ONE |
pmid:18682733
|
Chauvigné F et al. |
Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis. |
2011 |
PLoS ONE |
pmid:22087261
|
Bozek K et al. |
Regulation of clock-controlled genes in mammals. |
2009 |
PLoS ONE |
pmid:19287494
|
Leszczynska A et al. |
Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. |
2009 |
PLoS ONE |
pmid:20041128
|
Gas-Pascual E et al. |
Plant oxidosqualene metabolism: cycloartenol synthase-dependent sterol biosynthesis in Nicotiana benthamiana. |
2014 |
PLoS ONE |
pmid:25343375
|
Vallejo MC et al. |
Lipidomic analysis of extracellular vesicles from the pathogenic phase of Paracoccidioides brasiliensis. |
2012 |
PLoS ONE |
pmid:22745761
|
Hartwig T et al. |
Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize. |
2012 |
PLoS ONE |
pmid:22590578
|
Tebbets B et al. |
Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay. |
2012 |
PLoS ONE |
pmid:22574132
|
Oliaro-Bosso S et al. |
Characterization of the channel constriction allowing the access of the substrate to the active site of yeast oxidosqualene cyclase. |
2011 |
PLoS ONE |
pmid:21811565
|
Straud S et al. |
Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines. |
2010 |
PLoS ONE |
pmid:20661293
|
Chadwick W et al. |
Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. |
2011 |
PLoS ONE |
pmid:21738745
|
Mullins JG et al. |
Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola. |
2011 |
PLoS ONE |
pmid:21738598
|
Singh A and Prasad R |
Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints. |
2011 |
PLoS ONE |
pmid:21559392
|
Guan W et al. |
Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogen. |
2010 |
PLoS ONE |
pmid:20593017
|
Dutra RC et al. |
Preventive and therapeutic euphol treatment attenuates experimental colitis in mice. |
2011 |
PLoS ONE |
pmid:22073270
|
Arendrup MC et al. |
Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence. |
2010 |
PLoS ONE |
pmid:20404915
|
Solberg R et al. |
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. |
2010 |
PLoS ONE |
pmid:20231903
|
Kaddurah-Daouk R et al. |
Enteric microbiome metabolites correlate with response to simvastatin treatment. |
2011 |
PLoS ONE |
pmid:22022402
|
Chen CL et al. |
Euphol from Euphorbia tirucalli Negatively Modulates TGF-β Responsiveness via TGF-β Receptor Segregation inside Membrane Rafts. |
2015 |
PLoS ONE |
pmid:26448474
|