| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abetalipoproteinemia | D000012 | 7 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Leukemia, Hairy Cell | D007943 | 5 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
Total
4
lanosterol
lanosterol is a lipid of Sterol Lipids (ST) class. Lanosterol is associated with abnormalities such as Infection, Atherosclerosis, Myocardial Infarction, Chagas Disease and Fatty Liver. The involved functions are known as Signal, Cytokinesis, physiological aspects, Stereochemistry and ergosterol biosynthetic process. Lanosterol often locates in Body tissue, Membrane, Plasma membrane, Tissue membrane and Cytoskeletal Filaments. The associated genes with lanosterol are Retinoic Acid Response Element, P4HTM gene, CYP51A1 gene, HM13 gene and SC4MOL gene. The related lipids are pneumocysterol, Sterols, lanosteryl acetate, ebericol and cycloartenol. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of lanosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with lanosterol?
lanosterol is suspected in Atherosclerosis, Chagas Disease, vaginalis, hypercholesterolemia, Obesity, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with lanosterol
PubChem Associated disorders and diseases
What pathways are associated with lanosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with lanosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with lanosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with lanosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with lanosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with lanosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with lanosterol?
Knock-out
Knock-out are used in the study 'Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis.' (Ohyama K et al., 2009), Knock-out are used in the study 'Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.' (Warrilow AG et al., 2010) and Knock-out are used in the study 'Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.' (D'Agostino J et al., 2012).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with lanosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Horvath SE et al. | Metabolic link between phosphatidylethanolamine and triacylglycerol metabolism in the yeast Saccharomyces cerevisiae. | 2011 | Biochim. Biophys. Acta | pmid:21875690 |
| Krasowski MD et al. | The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. | 2011 | BMC Biochem. | pmid:21291553 |
| Nes WD | Biosynthesis of cholesterol and other sterols. | 2011 | Chem. Rev. | pmid:21902244 |
| Gleason JE et al. | Analysis of hypoxia and hypoxia-like states through metabolite profiling. | 2011 | PLoS ONE | pmid:21931840 |
| Sawai S and Saito K | Triterpenoid biosynthesis and engineering in plants. | 2011 | Front Plant Sci | pmid:22639586 |
| Cantu D et al. | Next generation sequencing provides rapid access to the genome of Puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust. | 2011 | PLoS ONE | pmid:21909385 |
| Stottmann RW et al. | Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo. | 2011 | PLoS Genet. | pmid:21912524 |
| Idkowiak J et al. | Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. | 2011 | J. Clin. Endocrinol. Metab. | pmid:21190981 |
| Hoot SJ et al. | The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity. | 2011 | BMC Microbiol. | pmid:21951709 |
| Jensen PA et al. | TIGER: Toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks. | 2011 | BMC Syst Biol | pmid:21943338 |
| Reynaud EG and Devos DP | Transitional forms between the three domains of life and evolutionary implications. | 2011 | Proc. Biol. Sci. | pmid:21920985 |
| Cabrito TR et al. | The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance. | 2011 | Biochem. J. | pmid:21831043 |
| Bisi-Johnson MA et al. | Evaluation of the antibacterial and anticancer activities of some South African medicinal plants. | 2011 | BMC Complement Altern Med | pmid:21329526 |
| D'Souza CA et al. | Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. | 2011 | MBio | pmid:21304167 |
| Choi MH et al. | Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. | 2011 | BMC Cancer | pmid:21824401 |
| Fakheri RJ and Javitt NB | Autoregulation of cholesterol synthesis: physiologic and pathophysiologic consequences. | 2011 | Steroids | pmid:20951718 |
| Koturbash I et al. | Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene. | 2011 | Environ. Health Perspect. | pmid:21147608 |
| Chen NH and Zhong JJ | p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells. | 2011 | Phytomedicine | pmid:21353507 |
| Zhong XH et al. | Effects of inotodiol extracts from inonotus obliquus on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line A549. | 2011 | Chin J Integr Med | pmid:21359924 |
| Leichtle AB et al. | Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men. | 2011 | Am. J. Clin. Nutr. | pmid:21940598 |