Yan LP et al. |
Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. |
2006 |
Life Sci. |
pmid:16472823
|
Tang W et al. |
Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells. |
2006 |
Life Sci. |
pmid:17007887
|
Nes WD et al. |
Sterol utilization and metabolism by Heliothis zea. |
1997 |
Lipids |
pmid:9438243
|
Mouritsen OG and Zuckermann MJ |
What's so special about cholesterol? |
2004 |
Lipids |
pmid:15726825
|
Zhou W et al. |
Evidence for multiple sterol methyl transferase pathways in Pneumocystis carinii. |
2002 |
Lipids |
pmid:12617472
|
Sekigawa Y et al. |
Purification and characterization of a cytochrome P450 isozyme catalyzing lanosterol 14 alpha-demethylation (P45014DM) in hamster liver. |
1995 |
Lipids |
pmid:8614296
|
Parish EJ et al. |
Syntheses of ring C oxysterols: inhibitors of sterol biosynthesis. |
2007 |
Lipids |
pmid:17393208
|
Jeong TM et al. |
Analysis of methylsterol fractions from twenty vegetable oils. |
1975 |
Lipids |
pmid:1186450
|
Smiljanic K et al. |
Aging induces tissue-specific changes in cholesterol metabolism in rat brain and liver. |
2013 |
Lipids |
pmid:24057446
|
Nes WR |
Role of sterols in membranes. |
1974 |
Lipids |
pmid:4607429
|
Lees ND et al. |
Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. |
1995 |
Lipids |
pmid:7791529
|
Abe I and Prestwich GD |
Identification of the active site of vertebrate oxidosqualene cyclase. |
1995 |
Lipids |
pmid:7791531
|
Gibbons GF |
The role of cytochrome P450 in the regulation of cholesterol biosynthesis. |
2002 |
Lipids |
pmid:12617470
|
Trzaskos JM et al. |
Microsomal enzymes of cholesterol biosynthesis from lanosterol: a progress report. |
1982 |
Lipids |
pmid:6806557
|
Kaneshiro ES |
Sterol metabolism in the opportunistic pathogen Pneumocystis: advances and new insights. |
2004 |
Lipids |
pmid:15638243
|
Sarkar CP and Cenedella RJ |
Reactivity of key metabolic sterols in standard colorimetric assays for cholesterol. |
1982 |
Lipids |
pmid:6177997
|
Shackleton CH |
Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesis. |
2012 |
Lipids |
pmid:21874273
|
Cenedella RJ |
Digitonide precipitable sterols: a reevaluation with special attention to lanosterol. |
1982 |
Lipids |
pmid:7050581
|
Johnson RC and Shah SN |
Binding of squalene, lanosterol, desmosterol, and cholesterol to proteins in brain and liver 105,000 g supernatant fractions: evidence for specific binding sites. |
1976 |
Lipids |
pmid:994754
|
Martirosyan DM et al. |
Amaranth oil application for coronary heart disease and hypertension. |
2007 |
Lipids Health Dis |
pmid:17207282
|
Machaba KE et al. |
In vivo anti-hyperlipidemic activity of the triterpene from the stem bark of Protorhus longifolia (Benrh) Engl. |
2014 |
Lipids Health Dis |
pmid:25127687
|
Wong J et al. |
Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. |
2007 |
Lipids Health Dis |
pmid:17408498
|
Berger A et al. |
Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. |
2004 |
Lipids Health Dis |
pmid:14969592
|
Guan SH et al. |
Structure elucidation and complete NMR spectral assignments of three new lanostanoid triterpenes with unprecedented Delta(16, 17) double bond from Ganoderma lucidum. |
2007 |
Magn Reson Chem |
pmid:17640004
|
D'Souza CA et al. |
Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. |
2011 |
MBio |
pmid:21304167
|
Vasanthanathan P et al. |
Classical QSAR study on chromene derivatives as lanosterol 14alpha- demethylase inhibitor: a non azole antifungal target. |
2006 |
Med Chem |
pmid:16848747
|
Stäubert C et al. |
Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells. |
2016 |
Med. Oncol. |
pmid:26698156
|
De Luca C and Valacchi G |
Surface lipids as multifunctional mediators of skin responses to environmental stimuli. |
2010 |
Mediators Inflamm. |
pmid:20981292
|
Ottaviani M et al. |
Lipid mediators in acne. |
2010 |
Mediators Inflamm. |
pmid:20871834
|
Tint GS and Salen G |
Evidence for the early reduction of the 24,25 double bond in the conversion of lanosterol to cholesterol in cerebrotendinous xanthomatosis. |
1977 |
Metab. Clin. Exp. |
pmid:865281
|
Cuzzopoli M et al. |
Effect of nephrectomy and cholesterol feeding on the metabolism of intravenously administered DL-mevalonate in the rat. |
1972 |
Metab. Clin. Exp. |
pmid:4641957
|
Gylling H et al. |
Hypolipidemic effect and mechanism of ketoconazole without and with cholestyramine in familial hypercholesterolemia. |
1991 |
Metab. Clin. Exp. |
pmid:1984567
|
Lindenthal B and von Bergmann K |
Urinary excretion and serum concentration of mevalonic acid during acute intake of alcohol. |
2000 |
Metab. Clin. Exp. |
pmid:10647065
|
Clarenbach JJ et al. |
Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis. |
2005 |
Metab. Clin. Exp. |
pmid:15736111
|
Zuckermann MJ et al. |
Modeling lipid-sterol bilayers: applications to structural evolution, lateral diffusion, and rafts. |
2004 |
Meth. Enzymol. |
pmid:15063652
|
Baumann K et al. |
Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris. |
2011 |
Microb. Cell Fact. |
pmid:22050768
|
Ahmad A et al. |
Evolution of ergosterol biosynthesis inhibitors as fungicidal against Candida. |
2010 |
Microb. Pathog. |
pmid:19835945
|
Wang X et al. |
Ganoderic acid A inhibits proliferation and invasion, and promotes apoptosis in human hepatocellular carcinoma cells. |
2017 |
Mol Med Rep |
pmid:28731159
|
Wang L et al. |
Euphol arrests breast cancer cells at the G1 phase through the modulation of cyclin D1, p21 and p27 expression. |
2013 |
Mol Med Rep |
pmid:23969579
|
Buckner FS et al. |
Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. |
2003 |
Mol. Biochem. Parasitol. |
pmid:14599667
|
Goad LJ et al. |
Sterols of ketoconazole-inhibited Leishmania mexicana mexicana promastigotes. |
1985 |
Mol. Biochem. Parasitol. |
pmid:4033689
|
Liendo A et al. |
Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes. |
1999 |
Mol. Biochem. Parasitol. |
pmid:10589983
|
Buckner FS et al. |
Cloning and heterologous expression of the Trypanosoma brucei lanosterol synthase gene. |
2000 |
Mol. Biochem. Parasitol. |
pmid:11071292
|
Lamb DC et al. |
Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis. |
2007 |
Mol. Biol. Evol. |
pmid:17567593
|
Freitas HF et al. |
Cloning, expression, purification and spectrophotometric analysis of lanosterol 14-alpha demethylase from Leishmania braziliensis (LbCYP51). |
2018 |
Mol. Biol. Rep. |
pmid:29363024
|
Gill BS et al. |
Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. |
2016 |
Mol. Biol. Rep. |
pmid:27640015
|
Ye X et al. |
Characterization of a human Sec14-like protein cDNA SEC14L3 highly homologous to human SPF/TAP. |
2004 |
Mol. Biol. Rep. |
pmid:15040456
|
Ling H et al. |
Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells. |
2009 |
Mol. Carcinog. |
pmid:18973184
|
Otte K et al. |
Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol. |
2003 |
Mol. Cell. Biol. |
pmid:12529392
|
Jin S et al. |
Meiosis activating sterol (MAS) regulate FSH-induced meiotic resumption of cumulus cell-enclosed porcine oocytes via PKC pathway. |
2006 |
Mol. Cell. Endocrinol. |
pmid:16500744
|
Xie H et al. |
Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes. |
2004 |
Mol. Cell. Endocrinol. |
pmid:15130520
|
Lepesheva GI and Waterman MR |
CYP51--the omnipotent P450. |
2004 |
Mol. Cell. Endocrinol. |
pmid:15026190
|
Rozman D et al. |
Pre-cholesterol precursors in gametogenesis. |
2005 |
Mol. Cell. Endocrinol. |
pmid:15836952
|
Bokal EV et al. |
Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome. |
2006 |
Mol. Cell. Endocrinol. |
pmid:16516374
|
Rozman D et al. |
Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis. |
2002 |
Mol. Cell. Endocrinol. |
pmid:11988326
|
Byskov AG et al. |
Role of meiosis activating sterols, MAS, in induced oocyte maturation. |
2002 |
Mol. Cell. Endocrinol. |
pmid:11988327
|
Cho SY et al. |
Cholesterol biosynthesis from lanosterol: differential inhibition of sterol delta 8-isomerase and other lanosterol-converting enzymes by tamoxifen. |
1998 |
Mol. Cells |
pmid:9638657
|
Ning G et al. |
3',5'-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14alpha-demethylase expression involved in follicle-stimulating hormone-induced mouse oocyte maturation. |
2008 |
Mol. Endocrinol. |
pmid:18467523
|
Halder SK et al. |
A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51). |
2002 |
Mol. Endocrinol. |
pmid:12145339
|
Hubbert ML et al. |
Regulation of hepatic Insig-2 by the farnesoid X receptor. |
2007 |
Mol. Endocrinol. |
pmid:17440045
|
Liu Y et al. |
Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells. |
2005 |
Mol. Endocrinol. |
pmid:15761033
|
van Nistelrooy JG et al. |
Isolation and molecular characterisation of the gene encoding eburicol 14 alpha-demethylase (cYP51) from Penicillium italicum. |
1996 |
Mol. Gen. Genet. |
pmid:8628233
|
Kaneshiro ES et al. |
The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference. |
2002 |
Mol. Microbiol. |
pmid:12010494
|
Hooff GP et al. |
Brain isoprenoids farnesyl pyrophosphate and geranylgeranyl pyrophosphate are increased in aged mice. |
2012 |
Mol. Neurobiol. |
pmid:22692983
|
Zhang H et al. |
Lanosterol metabolic product(s) is involved in primordial folliculogenesis and establishment of primordial follicle pool in mouse fetal ovary. |
2009 |
Mol. Reprod. Dev. |
pmid:18937335
|
Andersen MR et al. |
Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger. |
2008 |
Mol. Syst. Biol. |
pmid:18364712
|
Spitzer M et al. |
Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. |
2011 |
Mol. Syst. Biol. |
pmid:21694716
|
Owens CM et al. |
Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication. |
2010 |
Mol. Syst. Biol. |
pmid:20531405
|
Wang XL et al. |
Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi. |
2016 |
Molecules |
pmid:27775633
|
Mosa RA et al. |
In vivo antihyperglycemic activity of a lanosteryl triterpene from Protorhus longifolia. |
2015 |
Molecules |
pmid:26205060
|
Zhang SS et al. |
Three new lanostanoids from the mushroom Ganoderma tropicum. |
2015 |
Molecules |
pmid:25690289
|
Brycki B et al. |
Synthesis, spectroscopic and semiempirical studies of new quaternary alkylammonium conjugates of sterols. |
2013 |
Molecules |
pmid:24317524
|
AÄimoviÄ J and Rozman D |
Steroidal triterpenes of cholesterol synthesis. |
2013 |
Molecules |
pmid:23558541
|
Liu J and Nes WD |
Steroidal triterpenes: design of substrate-based inhibitors of ergosterol and sitosterol synthesis. |
2009 |
Molecules |
pmid:19924096
|
Franzot SP and Hamdan JS |
Effects of three azole derivatives on the lipids of different strains of Cryptococcus neoformans. |
1995 May-Jun |
Mycoses |
pmid:8531929
|
Ogbuewu IP et al. |
The potentiality of medicinal plants as the source of new contraceptive principles in males. |
2011 |
N Am J Med Sci |
pmid:22540095
|
Rani S et al. |
Phytochemical investigation of the seeds of Althea officinalis L. |
2010 |
Nat. Prod. Res. |
pmid:20803381
|
Shiono Y et al. |
N-Phenethylhexadecanamide from the edible mushroom Laetiporus sulphureus. |
2005 |
Nat. Prod. Res. |
pmid:15938143
|
Li C et al. |
Ganoderic acid Sz, a new lanostanoid from the mushroom Ganoderma lucidum. |
2005 |
Nat. Prod. Res. |
pmid:15938193
|
Li C et al. |
New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum. |
2006 |
Nat. Prod. Res. |
pmid:17050181
|
Xie LR et al. |
A new cyclonerol derivative from a marine-derived fungus Ascotricha sp. ZJ-M-5. |
2013 |
Nat. Prod. Res. |
pmid:22840229
|
Susanti D et al. |
Friedelin and lanosterol from Garcinia prainiana stimulated glucose uptake and adipocytes differentiation in 3T3-L1 adipocytes. |
2013 |
Nat. Prod. Res. |
pmid:22988818
|
Jamila N et al. |
Molecular docking studies and in vitro cholinesterase enzyme inhibitory activities of chemical constituents of Garcinia hombroniana. |
2015 |
Nat. Prod. Res. |
pmid:25219673
|
Ruan W et al. |
Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growth. |
2014 |
Nat. Prod. Res. |
pmid:25032738
|
Zhang XQ et al. |
Triterpenoids with neurotrophic activity from Ganoderma lucidum. |
2011 |
Nat. Prod. Res. |
pmid:21671206
|
Thoma R et al. |
Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. |
2004 |
Nature |
pmid:15525992
|
DOREE C et al. |
Position of the hydroxyl group in lanosterol. |
1949 |
Nature |
pmid:18107580
|
Zhao L et al. |
Lanosterol reverses protein aggregation in cataracts. |
2015 |
Nature |
pmid:26200341
|
Hejtmancik JF |
Ophthalmology: Cataracts dissolved. |
2015 |
Nature |
pmid:26200338
|
Wang J et al. |
Eburicoic acid from Laetiporus sulphureus (Bull.:Fr.) Murrill attenuates inflammatory responses through inhibiting LPS-induced activation of PI3K/Akt/mTOR/NF-κB pathways in RAW264.7 cells. |
2017 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:28577049
|
van den Kommer TN et al. |
The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline. |
2012 |
Neurobiol. Aging |
pmid:21482441
|
Teunissen CE et al. |
Serum cholesterol, precursors and metabolites and cognitive performance in an aging population. |
2003 Jan-Feb |
Neurobiol. Aging |
pmid:12493560
|
Valenza M et al. |
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease. |
2007 |
Neurobiol. Dis. |
pmid:17702587
|
Kuehnle K et al. |
Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice. |
2009 |
Neurochem. Res. |
pmid:19115107
|
Dutra RC et al. |
Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system. |
2012 |
Neuropharmacology |
pmid:22613837
|
Besga A et al. |
Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms. |
2012 |
Neurosci. Lett. |
pmid:22281444
|
Solomon A et al. |
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. |
2009 |
Neurosci. Lett. |
pmid:19560513
|
Leoni V et al. |
Whole body cholesterol metabolism is impaired in Huntington's disease. |
2011 |
Neurosci. Lett. |
pmid:21406216
|
Thelen KM et al. |
Cholesterol synthesis rate in human hippocampus declines with aging. |
2006 |
Neurosci. Lett. |
pmid:16701946
|
Dutra RC et al. |
The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε. |
2015 |
Neuroscience |
pmid:26143011
|