Barker KS et al. |
Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans. |
2004 |
J. Antimicrob. Chemother. |
pmid:15201233
|
Kavtaradze LK et al. |
A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures. |
2004 |
Steroids |
pmid:15465116
|
Godio RP et al. |
Agrobacterium tumefaciens-mediated transformation of the antitumor clavaric acid-producing basidiomycete Hypholoma sublateritium. |
2004 |
Curr. Genet. |
pmid:15480676
|
Wu X et al. |
New lanostane-type triterpenes from Fomes officinalis. |
2004 |
Chem. Pharm. Bull. |
pmid:15516768
|
Adachi M et al. |
Compound heterozygous mutations of cytochrome P450 oxidoreductase gene (POR) in two patients with Antley-Bixler syndrome. |
2004 |
Am. J. Med. Genet. A |
pmid:15264278
|
Henriksen J et al. |
Vesicle fluctuation analysis of the effects of sterols on membrane bending rigidity. |
2004 |
Eur. Biophys. J. |
pmid:15221234
|
Sheng C et al. |
Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions. |
2004 |
J. Biomol. Struct. Dyn. |
pmid:15214809
|
Xie H et al. |
Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes. |
2004 |
Mol. Cell. Endocrinol. |
pmid:15130520
|
Chen YG et al. |
Ananosic acids B and C, two new 18(13-->12)-abeo-lanostane triterpenoids from Kadsura ananosma. |
2004 |
J. Nat. Prod. |
pmid:15165154
|
Moodley N et al. |
Eucosterol-type nortriterpenoids from Merwilla natalensis. |
2004 |
J. Nat. Prod. |
pmid:15165167
|
Kavtaradze LK et al. |
Efficient routes to epimerically-pure side-chain derivatives of lanosterol. |
2004 |
Steroids |
pmid:15183688
|
Shim SH et al. |
New lanostane-type triterpenoids from Ganoderma applanatum. |
2004 |
J. Nat. Prod. |
pmid:15270562
|
Martin-Creuzburg D and Von Elert E |
Impact of 10 dietary sterols on growth and reproduction of Daphnia galeata. |
2004 |
J. Chem. Ecol. |
pmid:15139303
|
Beattie ME et al. |
Sterol structure determines miscibility versus melting transitions in lipid vesicles. |
2005 |
Biophys. J. |
pmid:15951379
|
Beasley CL et al. |
Reductions in cholesterol and synaptic markers in association cortex in mood disorders. |
2005 |
Bipolar Disord |
pmid:16176438
|
Lodeiro S et al. |
Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase. |
2005 |
J. Am. Chem. Soc. |
pmid:16218577
|
Davenport RJ |
How low can you go? |
2005 |
Sci Aging Knowledge Environ |
pmid:15772415
|
Domeño C et al. |
Determination of sterols in biological samples by SPME with on-fiber derivatization and GC/FID. |
2005 |
Anal Bioanal Chem |
pmid:15827725
|
Gao PH et al. |
In vitro antifungal activity of ZJ-522, a new triazole restructured from fluconazole and butenafine, against clinically important fungi in comparison with fluconazole and butenafine. |
2005 |
Biol. Pharm. Bull. |
pmid:16079485
|
Shimokawa O et al. |
Relationship between MIC and minimum sterol 14{alpha}-demethylation-inhibitory concentration as a factor in evaluating activities of azoles against various fungal species. |
2005 |
J. Clin. Microbiol. |
pmid:16272484
|
Kwok Y et al. |
A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. |
2005 |
Anesth. Analg. |
pmid:16037156
|
Hucke O et al. |
The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease. |
2005 |
J. Med. Chem. |
pmid:16107140
|
Dantas-Leite L et al. |
Antiproliferative synergism of azasterols and antifolates against Toxoplasma gondii. |
2005 |
Int. J. Antimicrob. Agents |
pmid:15664482
|
Sakurai N et al. |
Cancer preventive agents. Part 1: chemopreventive potential of cimigenol, cimigenol-3,15-dione, and related compounds. |
2005 |
Bioorg. Med. Chem. |
pmid:15670948
|
Yoshikawa K et al. |
Lanostane triterpenoids and triterpene glycosides from the fruit body of Fomitopsis pinicola and their inhibitory activity against COX-1 and COX-2. |
2005 |
J. Nat. Prod. |
pmid:15679320
|
Chevy F et al. |
Sterol profiling of amniotic fluid: a routine method for the detection of distal cholesterol synthesis deficit. |
2005 |
Prenat. Diagn. |
pmid:16231320
|
Scheidt HA et al. |
Diffusion of cholesterol and its precursors in lipid membranes studied by 1H pulsed field gradient magic angle spinning NMR. |
2005 |
Biophys. J. |
pmid:16085761
|
Wada S and Tanaka R |
Synthetic lanostane-type triterpenoids as inhibitors of DNA topoisomerase II. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15914002
|
Li CH et al. |
Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. |
2005 |
Life Sci. |
pmid:15878354
|
Akihisa T et al. |
Oxygenated lanostane-type triterpenoids from the fungus ganodermalucidum. |
2005 |
J. Nat. Prod. |
pmid:15844948
|
Yoshikawa K et al. |
Cytotoxic constituents of the fruit body of Daedalea dickisii. |
2005 |
J. Nat. Prod. |
pmid:15974617
|
Shiono Y et al. |
N-Phenethylhexadecanamide from the edible mushroom Laetiporus sulphureus. |
2005 |
Nat. Prod. Res. |
pmid:15938143
|
Li C et al. |
Ganoderic acid Sz, a new lanostanoid from the mushroom Ganoderma lucidum. |
2005 |
Nat. Prod. Res. |
pmid:15938193
|
Buurman ET et al. |
Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. |
2005 |
Antimicrob. Agents Chemother. |
pmid:15917573
|
Huff MW and Telford DE |
Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear. |
2005 |
Trends Pharmacol. Sci. |
pmid:15951028
|
Shao HJ et al. |
A new cytotoxic lanostane triterpenoid from the basidiomycete Hebeloma versipelle. |
2005 |
J. Antibiot. |
pmid:16506701
|
Cournia Z et al. |
A molecular mechanics force field for biologically important sterols. |
2005 |
J Comput Chem |
pmid:16028234
|
Rukachaisirikul V et al. |
Friedolanostanes and lanostanes from the leaves of Garcinia hombroniana. |
2005 |
J. Nat. Prod. |
pmid:16124765
|
Dai HF et al. |
Norlanostane triterpenoidal saponins from the marine sponge melophlussarassinorum. |
2005 |
J. Nat. Prod. |
pmid:16124767
|
Ott RG et al. |
Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. |
2005 |
Biochim. Biophys. Acta |
pmid:15951236
|
Uthman A et al. |
Fluconazole upregulates sconC expression and inhibits sulphur metabolism in Microsporum canis. |
2005 |
Fungal Genet. Biol. |
pmid:15922636
|
Venteclef N et al. |
The imidazoline-like drug S23515 affects lipid metabolism in hepatocyte by inhibiting the oxidosqualene: lanosterol cyclase activity. |
2005 |
Biochem. Pharmacol. |
pmid:15763540
|
Prasad R and Kapoor K |
Multidrug resistance in yeast Candida. |
2005 |
Int. Rev. Cytol. |
pmid:15598470
|
O'Brien M et al. |
Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity. |
2005 |
Plant Physiol. |
pmid:16169959
|
Harwood HJ et al. |
Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase. |
2005 |
J. Lipid Res. |
pmid:15604516
|
Fink M et al. |
Cholesterogenic lanosterol 14alpha-demethylase (CYP51) is an immediate early response gene. |
2005 |
Endocrinology |
pmid:16123160
|
Pencer J et al. |
Bilayer thickness and thermal response of dimyristoylphosphatidylcholine unilamellar vesicles containing cholesterol, ergosterol and lanosterol: a small-angle neutron scattering study. |
2005 |
Biochim. Biophys. Acta |
pmid:16386704
|
Clarenbach JJ et al. |
Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis. |
2005 |
Metab. Clin. Exp. |
pmid:15736111
|
Song BL et al. |
Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol. |
2005 |
Cell Metab. |
pmid:16054061
|
Rozman D et al. |
Pre-cholesterol precursors in gametogenesis. |
2005 |
Mol. Cell. Endocrinol. |
pmid:15836952
|
Suárez Y et al. |
Sterol stringency of proliferation and cell cycle progression in human cells. |
2005 |
Biochim. Biophys. Acta |
pmid:15904877
|
Huster D et al. |
Desmosterol may replace cholesterol in lipid membranes. |
2005 |
Biophys. J. |
pmid:15596512
|
Ståhlberg N et al. |
Exploring hepatic hormone actions using a compilation of gene expression profiles. |
2005 |
BMC Physiol. |
pmid:15953391
|
Doddapaneni H et al. |
Genome-wide structural and evolutionary analysis of the P450 monooxygenase genes (P450ome) in the white rot fungus Phanerochaete chrysosporium: evidence for gene duplications and extensive gene clustering. |
2005 |
BMC Genomics |
pmid:15955240
|
Liu Y et al. |
Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells. |
2005 |
Mol. Endocrinol. |
pmid:15761033
|
Hildenbrand MF and Bayerl TM |
Differences in the modulation of collective membrane motions by ergosterol, lanosterol, and cholesterol: a dynamic light scattering study. |
2005 |
Biophys. J. |
pmid:15764657
|
Hajjaj H et al. |
Effect of 26-oxygenosterols from Ganoderma lucidum and their activity as cholesterol synthesis inhibitors. |
2005 |
Appl. Environ. Microbiol. |
pmid:16000773
|
Hajjaj H et al. |
Aspergillus oryzae produces compounds inhibiting cholesterol biosynthesis downstream of dihydrolanosterol. |
2005 |
FEMS Microbiol. Lett. |
pmid:15621432
|
Sun S et al. |
The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry. |
2005 |
Anal. Biochem. |
pmid:15582556
|
Zanno A et al. |
MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51. |
2005 Apr-May |
Biochim. Biophys. Acta |
pmid:15863094
|
Pemán J et al. |
Voriconazole in the management of nosocomial invasive fungal infections. |
2006 |
Ther Clin Risk Manag |
pmid:18360588
|
Bursill CA and Roach PD |
Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells. |
2006 |
J. Agric. Food Chem. |
pmid:16506810
|
Sharpe RL et al. |
Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol. |
2006 |
Reprod. Biol. Endocrinol. |
pmid:17118198
|
Jin S et al. |
Meiosis activating sterol (MAS) regulate FSH-induced meiotic resumption of cumulus cell-enclosed porcine oocytes via PKC pathway. |
2006 |
Mol. Cell. Endocrinol. |
pmid:16500744
|
Wang F et al. |
cDNA cloning, genomic structure and expression analysis of the bovine lanosterol 14alpha-demethylase (CYP51) in gonads. |
2006 |
Biol. Pharm. Bull. |
pmid:16508140
|
Trösken ER et al. |
Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. |
2006 |
Toxicology |
pmid:16989930
|
Walters KA et al. |
Host-specific response to HCV infection in the chimeric SCID-beige/Alb-uPA mouse model: role of the innate antiviral immune response. |
2006 |
PLoS Pathog. |
pmid:16789836
|
Vasanthanathan P et al. |
Influence of thermodynamic parameter in Lanosterol 14alpha-demethylase inhibitory activity as antifungal agents: a QSAR approach. |
2006 |
Biol. Pharm. Bull. |
pmid:16755030
|
Pietila MP et al. |
Cloning and characterization of CYP51 from Mycobacterium avium. |
2006 |
Am. J. Respir. Cell Mol. Biol. |
pmid:16543605
|
Tian Z et al. |
Cytotoxicity of cycloartane triterpenoids from aerial part of Cimicifuga foetida. |
2006 |
Fitoterapia |
pmid:16300906
|
Shahedi V et al. |
Domain-formation in DOPC/SM bilayers studied by pfg-NMR: effect of sterol structure. |
2006 |
Biophys. J. |
pmid:16829566
|
Bennati AM et al. |
Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis. |
2006 |
Biochim. Biophys. Acta |
pmid:16784888
|
Yan LP et al. |
Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. |
2006 |
Life Sci. |
pmid:16472823
|
Singh DK and Porter TD |
Inhibition of sterol 4alpha-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis. |
2006 |
J. Nutr. |
pmid:16484558
|
Polo MP and de Bravo MG |
Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. |
2006 |
Biochem. Cell Biol. |
pmid:16462894
|
Thyagarajan A et al. |
Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion. |
2006 |
Int. J. Mol. Med. |
pmid:16964420
|
de Silva ED et al. |
Lanostane triterpenoids from the Sri Lankan basidiomycete Ganoderma applanatum. |
2006 |
J. Nat. Prod. |
pmid:16933889
|
Riddle LA and Guiochon G |
Separation of free sterols by high temperature liquid chromatography. |
2006 |
J Chromatogr A |
pmid:17055522
|
Kolesnikova MD et al. |
Lanosterol biosynthesis in plants. |
2006 |
Arch. Biochem. Biophys. |
pmid:16445886
|
He K et al. |
Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products. |
2006 |
J Chromatogr A |
pmid:16515793
|
Ramachandran SA et al. |
Synthetic studies toward highly functionalized 5beta-lanosterol derivatives: a versatile approach utilizing anionic cycloaddition. |
2006 |
J. Org. Chem. |
pmid:16872199
|
Megha O et al. |
Cholesterol precursors stabilize ordinary and ceramide-rich ordered lipid domains (lipid rafts) to different degrees. Implications for the Bloch hypothesis and sterol biosynthesis disorders. |
2006 |
J. Biol. Chem. |
pmid:16735517
|
Li C et al. |
New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum. |
2006 |
Nat. Prod. Res. |
pmid:17050181
|
Suzuki M et al. |
Lanosterol synthase in dicotyledonous plants. |
2006 |
Plant Cell Physiol. |
pmid:16531458
|
Sawai S et al. |
Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes. |
2006 |
Plant Cell Physiol. |
pmid:16531457
|
Wu TK et al. |
Site-saturated mutagenesis of histidine 234 of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase demonstrates dual functions in cyclization and rearrangement reactions. |
2006 |
J. Am. Chem. Soc. |
pmid:16683806
|
Kojima M et al. |
Cloning of chicken lanosterol 14alpha-demethylase (CYP51) cDNA: discovery of a testis-specific CYP51 transcript. |
2006 |
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. |
pmid:16945562
|
Zhu J et al. |
Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14alpha-demethylase (CYP51) of fungi. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16905318
|
Vasanthanathan P et al. |
Classical QSAR study on chromene derivatives as lanosterol 14alpha- demethylase inhibitor: a non azole antifungal target. |
2006 |
Med Chem |
pmid:16848747
|
Wang C et al. |
Lanosterol 14alpha-demethylase expression in the mouse ovary and its participation in cumulus-enclosed oocyte spontaneous meiotic maturation in vitro. |
2006 |
Theriogenology |
pmid:16650467
|
Tang W et al. |
Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells. |
2006 |
Life Sci. |
pmid:17007887
|
David Nes W and Nichols SD |
Phytosterol biosynthesis pathway in Mortierella alpina. |
2006 |
Phytochemistry |
pmid:16647729
|
Sheng C et al. |
Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking. |
2006 |
J. Med. Chem. |
pmid:16610794
|
Wu TK et al. |
Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions. |
2006 |
Org. Lett. |
pmid:16562881
|
Rebolj K et al. |
Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers. |
2006 |
Biochim. Biophys. Acta |
pmid:16857161
|
Mannock DA et al. |
Comparative calorimetric and spectroscopic studies of the effects of lanosterol and cholesterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes. |
2006 |
Biophys. J. |
pmid:16905603
|
Henriksen J et al. |
Universal behavior of membranes with sterols. |
2006 |
Biophys. J. |
pmid:16326903
|
Bokal EV et al. |
Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome. |
2006 |
Mol. Cell. Endocrinol. |
pmid:16516374
|
Stottrup BL and Keller SL |
Phase behavior of lipid monolayers containing DPPC and cholesterol analogs. |
2006 |
Biophys. J. |
pmid:16461392
|
Thelen KM et al. |
Cholesterol synthesis rate in human hippocampus declines with aging. |
2006 |
Neurosci. Lett. |
pmid:16701946
|