Xiong Q et al. |
Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway. |
2009 |
PLoS Pathog. |
pmid:19283084
|
Wada A et al. |
Expression of functional bovine cholesterol side chain cleavage cytochrome P450 (P450scc) in Escherichia coli. |
1991 |
Arch. Biochem. Biophys. |
pmid:1929405
|
Palaniappan M and Menon KM |
Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells. |
2009 |
Biol. Reprod. |
pmid:19299314
|
Sharma I et al. |
Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis. |
2010 |
Fertil. Steril. |
pmid:19324352
|
Olsen BN et al. |
Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation. |
2009 |
J. Am. Chem. Soc. |
pmid:19334779
|
Chatterjee S et al. |
Identification of novel genes and pathways regulating SREBP transcriptional activity. |
2009 |
PLoS ONE |
pmid:19381295
|
Romanelli RJ et al. |
Insulin-like growth factor-I-stimulated Akt phosphorylation and oligodendrocyte progenitor cell survival require cholesterol-enriched membranes. |
2009 |
J. Neurosci. Res. |
pmid:19382214
|
Morello F et al. |
LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms. |
2009 |
Atherosclerosis |
pmid:19426978
|
Villeneuve DL et al. |
Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor. |
2009 |
Environ. Health Perspect. |
pmid:19440503
|
Liu J et al. |
Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol. |
2009 |
Arch. Biochem. Biophys. |
pmid:19464253
|
Andreone L et al. |
Regulation of inhibin/activin expression in rat early antral follicles. |
2009 |
Mol. Cell. Endocrinol. |
pmid:19464342
|
Ma YB et al. |
[Activation of sterol regulatory element binding protein and its involvement in endothelial cell migration]. |
2009 |
Zhonghua Bing Li Xue Za Zhi |
pmid:19489226
|
Diczfalusy U et al. |
Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide. |
2009 |
J. Lipid Res. |
pmid:19502589
|
Trasino SE et al. |
Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells. |
2009 |
Mol. Cancer Ther. |
pmid:19531574
|
Perttilä J et al. |
OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. |
2009 |
J. Mol. Med. |
pmid:19554302
|
Kwon HJ et al. |
Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol. |
2009 |
Cell |
pmid:19563754
|
Lee PC and DeBose-Boyd RA |
Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells. |
2010 |
J. Lipid Res. |
pmid:19617589
|
Li T and Chiang JY |
Regulation of bile acid and cholesterol metabolism by PPARs. |
2009 |
PPAR Res |
pmid:19636418
|
Yu PL et al. |
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. |
2009 |
J. Cell. Biochem. |
pmid:19639602
|
Mitomo H et al. |
Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease? |
2009 |
J. Am. Chem. Soc. |
pmid:19658396
|
Li H et al. |
Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. |
2009 |
J. Biol. Chem. |
pmid:19687008
|
Calleros L et al. |
Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells. |
2009 |
Carcinogenesis |
pmid:19700418
|
Perales S et al. |
Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia. |
2009 |
J. Biomed. Biotechnol. |
pmid:19727411
|
Chisaki I et al. |
Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver. |
2009 |
Biochim. Biophys. Acta |
pmid:19728987
|
Owen DM et al. |
Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor. |
2009 |
Virology |
pmid:19751943
|
Crow JA et al. |
Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids. |
2010 |
Biochim. Biophys. Acta |
pmid:19761868
|
Bauman DR et al. |
25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805370
|
Schüle R et al. |
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis. |
2010 |
J. Lipid Res. |
pmid:19812052
|
Trousson A et al. |
Cross-talk between oxysterols and glucocorticoids: differential regulation of secreted phopholipase A2 and impact on oligodendrocyte death. |
2009 |
PLoS ONE |
pmid:19956653
|
Amirak E et al. |
Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:19958749
|
Jesch ED et al. |
Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells. |
2009 |
Nutr Res |
pmid:19963159
|
Krycer JR et al. |
Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3. |
2009 |
PLoS ONE |
pmid:20041144
|
Ando H et al. |
Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro. |
2010 |
Biochim. Biophys. Acta |
pmid:20045741
|
Constantino CX et al. |
Insulin-like growth factor-I stimulates steroidogenesis in rabbit luteal cells. |
1991 |
Endocrinology |
pmid:2004596
|
Bansal N et al. |
Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents. |
1991 |
FASEB J. |
pmid:2004665
|
Patel MB et al. |
Liver x receptor: a novel therapeutic target. |
2008 Mar-Apr |
Indian J Pharm Sci |
pmid:20046702
|
Leighton JK et al. |
Activation of the silent endogenous cholesterol-7-alpha-hydroxylase gene in rat hepatoma cells: a new complementation group having resistance to 25-hydroxycholesterol. |
1991 |
Mol. Cell. Biol. |
pmid:2005896
|
Stottrup BL et al. |
Taking another look with fluorescence microscopy: image processing techniques in Langmuir monolayers for the twenty-first century. |
2010 |
Biochim. Biophys. Acta |
pmid:20067758
|
Ishii H et al. |
Analysis of the 22-NBD-cholesterol transfer between liposome membranes and its relation to the intermembrane exchange of 25-hydroxycholesterol. |
2010 |
Colloids Surf B Biointerfaces |
pmid:20122819
|
Nunomura S et al. |
Oxysterol represses high-affinity IgE receptor-stimulated mast cell activation in Liver X receptor-dependent and -independent manners. |
2010 |
FEBS Lett. |
pmid:20138879
|
Furuita K et al. |
Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies. |
2010 |
J. Biol. Chem. |
pmid:20178991
|
Jin L et al. |
Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma. |
2010 |
Mol. Endocrinol. |
pmid:20203100
|
Wang Y et al. |
A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol). |
2010 |
Biochim. Biophys. Acta |
pmid:20211758
|
Vallim T and Salter AM |
Regulation of hepatic gene expression by saturated fatty acids. |
2010 Apr-Jun |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:20227267
|
Solberg R et al. |
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. |
2010 |
PLoS ONE |
pmid:20231903
|
Jiménez-López JM et al. |
Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids. |
2010 |
Lipids Health Dis |
pmid:20338039
|
Dugas B et al. |
Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol. |
2010 |
Eur J Nutr |
pmid:20339855
|
Dharmarajan AM et al. |
Estradiol regulation of the rabbit corpus luteum: in vivo and in vitro studies. |
1991 |
Endocrinology |
pmid:2036954
|
Ecker J et al. |
Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes. |
2010 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:20385828
|
Hartman IZ et al. |
Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets. |
2010 |
J. Biol. Chem. |
pmid:20406816
|
Ruchala P et al. |
Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids. |
2010 |
PLoS ONE |
pmid:20418958
|
Mintzer E et al. |
Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes. |
2010 |
Chem. Phys. Lipids |
pmid:20471966
|
Borthwick F et al. |
Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype. |
2010 |
Clin. Sci. |
pmid:20491656
|
Hu J et al. |
Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones. |
2010 |
Nutr Metab (Lond) |
pmid:20515451
|
Aye IL et al. |
Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity. |
2010 |
Biochim. Biophys. Acta |
pmid:20570635
|
Menon KM et al. |
Molecular regulation of gonadotropin receptor expression: relationship to sterol metabolism. |
2010 |
Mol. Cell. Endocrinol. |
pmid:20570710
|
Ullrich C et al. |
Effects of cholesterol and its 24S-OH and 25-OH oxysterols on choline acetyltransferase-positive neurons in brain slices. |
2010 |
Pharmacology |
pmid:20571288
|
Palozza P et al. |
Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression. |
2011 |
J. Nutr. Biochem. |
pmid:20573495
|
Shoemaker JE et al. |
Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk. |
2010 |
BMC Syst Biol |
pmid:20579396
|
Tao JL et al. |
Lipids-induced apoptosis is aggravated by acyl-coenzyme A: cholesterol acyltransferase inhibitor. |
2010 |
Chin. Med. Sci. J. |
pmid:20598228
|
Hess D et al. |
Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells. |
2010 |
PLoS ONE |
pmid:20613975
|
Perales S et al. |
Fish oil supplementation reverses the effect of cholesterol on apoptotic gene expression in smooth muscle cells. |
2010 |
Lipids Health Dis |
pmid:20630092
|
Gu Y et al. |
Gossypolone suppresses progesterone synthesis in bovine luteal cells. |
1991 |
J. Steroid Biochem. Mol. Biol. |
pmid:2064986
|
Kobuna H et al. |
Multivesicular body formation requires OSBP-related proteins and cholesterol. |
2010 |
PLoS Genet. |
pmid:20700434
|
Xu L et al. |
Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate. |
2010 |
Lipids |
pmid:20700770
|
Heretsch P et al. |
Modulators of the hedgehog signaling pathway. |
2010 |
Bioorg. Med. Chem. |
pmid:20708941
|
Dasari B et al. |
The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells. |
2010 |
BMC Ophthalmol |
pmid:20836858
|
Chang LL et al. |
Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells. |
2010 |
Toxicol. Sci. |
pmid:20837582
|
Berrodin TJ et al. |
Identification of 5α, 6α-epoxycholesterol as a novel modulator of liver X receptor activity. |
2010 |
Mol. Pharmacol. |
pmid:20837678
|
Rujoi M et al. |
Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells. |
2010 |
PLoS ONE |
pmid:20877719
|
Banerji S et al. |
Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα. |
2010 |
Mol. Biol. Cell |
pmid:20881054
|
Saucier SE et al. |
Oxygenation of desmosterol and cholesterol in cell cultures. |
1990 |
J. Lipid Res. |
pmid:2090711
|
Malik AK et al. |
5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis. |
2010 |
PLoS ONE |
pmid:21042414
|
Nguyen VP et al. |
25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner. |
2010 |
J Angiogenes Res |
pmid:21070649
|
Roby KF and Terranova PF |
Effects of tumor necrosis factor-alpha in vitro on steroidogenesis of healthy and atretic follicles of the rat: theca as a target. |
1990 |
Endocrinology |
pmid:2109690
|
Seillan C |
Oxysterol mediated changes in fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells. |
1990 |
Lipids |
pmid:2110280
|
McDonald JG and Russell DW |
Editorial: 25-Hydroxycholesterol: a new life in immunology. |
2010 |
J. Leukoc. Biol. |
pmid:21123296
|
Bai Q et al. |
Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells. |
2011 |
Atherosclerosis |
pmid:21146170
|
Matsui M et al. |
Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter. |
2010 |
Chem. Biol. |
pmid:21168770
|
Panini SR et al. |
Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line. |
1990 |
J. Biol. Chem. |
pmid:2117604
|
Aye IL et al. |
Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors. |
2011 |
Placenta |
pmid:21208656
|
den Uyl D et al. |
(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis. |
2011 |
Arthritis Res. Ther. |
pmid:21241491
|
Boyce S et al. |
Reconstructed skin from cultured human keratinocytes and fibroblasts on a collagen-glycosaminoglycan biopolymer substrate. |
1990 |
Skin Pharmacol. |
pmid:2127678
|
Plasen D et al. |
Initial response of endothelial cells to acute stimulation with a lipid component: increase cyclooxygenase activity by induction of COX-2 through activation of tyrosine kinase. |
2010 |
J Med Assoc Thai |
pmid:21299081
|
Lappano R et al. |
The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes. |
2011 |
PLoS ONE |
pmid:21304949
|
Sonawane PJ et al. |
Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension. |
2011 |
PLoS ONE |
pmid:21304971
|
Olsen BN et al. |
25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes. |
2011 |
Biophys. J. |
pmid:21320439
|
Nantia EA et al. |
Effects of the methanol extract of Basella alba L (Basellaceae) on steroid production in Leydig cells. |
2011 |
Int J Mol Sci |
pmid:21339992
|
Jo Y et al. |
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
2011 |
J. Biol. Chem. |
pmid:21343306
|
Jusakul A et al. |
Mechanisms of oxysterol-induced carcinogenesis. |
2011 |
Lipids Health Dis |
pmid:21388551
|
Clariana M and GarcÃa-Regueiro JA |
Effect of high pressure processing on cholesterol oxidation products in vacuum packaged sliced dry-cured ham. |
2011 |
Food Chem. Toxicol. |
pmid:21426921
|
Shan PF et al. |
Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells. |
2011 |
PLoS ONE |
pmid:21437254
|
Bielska AA et al. |
Synthesis of the enantiomer of the oxysterol-antagonist LY295427. |
2011 Sep-Oct |
Steroids |
pmid:21470559
|
Siam A et al. |
Comparative modeling of 25-hydroxycholesterol-7α-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations. |
2012 |
J Mol Model |
pmid:21541746
|
Medina MW et al. |
Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake. |
2011 |
PLoS ONE |
pmid:21559365
|
Kamisuki S et al. |
Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. |
2011 |
J. Med. Chem. |
pmid:21561152
|
Honda A et al. |
Cholesterol 25-hydroxylation activity of CYP3A. |
2011 |
J. Lipid Res. |
pmid:21576599
|
Vejux A et al. |
Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments. |
2011 |
J Ophthalmol |
pmid:21577274
|
Gu Y et al. |
Inhibitory effect of gossypol on steroidogenic pathways in cultured bovine luteal cells. |
1990 |
Biochem. Biophys. Res. Commun. |
pmid:2162666
|
Diczfalusy U and Björkhem I |
Still another activity by the highly promiscuous enzyme CYP3A4: 25-hydroxylation of cholesterol. |
2011 |
J. Lipid Res. |
pmid:21652732
|