Appukuttan A et al. |
Oxysterol-induced apoptosis of smooth muscle cells is under the control of a soluble adenylyl cyclase. |
2013 |
Cardiovasc. Res. |
pmid:23729662
|
Ni J et al. |
Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells. |
2013 |
Lipids Health Dis |
pmid:23570453
|
Eibinger G et al. |
On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment. |
2013 |
Exp. Cell Res. |
pmid:23541792
|
Ohgane K et al. |
Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site. |
2013 |
Chem. Biol. |
pmid:23521797
|
Shackleford G et al. |
Differential regulation of Wnt/beta-catenin signaling by Liver X Receptors in Schwann cells and oligodendrocytes. |
2013 |
Biochem. Pharmacol. |
pmid:23500534
|
Ichikawa T et al. |
25-hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κB dependent pathway. |
2013 |
Exp. Cell Res. |
pmid:23485764
|
Stulov SV et al. |
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells. |
2013 |
Bioorg. Med. Chem. Lett. |
pmid:23466231
|
Waltl S et al. |
25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line. |
2013 |
Neurosci. Lett. |
pmid:23347841
|
Wu CA et al. |
An evaluation of the mechanism of ABCA7 on cellular lipid release in ABCA7-HEC293 cell. |
2013 |
Chin. Med. J. |
pmid:23324282
|
Liu SY et al. |
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. |
2013 |
Immunity |
pmid:23273844
|
Blanc M et al. |
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. |
2013 |
Immunity |
pmid:23273843
|
Tanaka AR et al. |
p38MAPK and Rho-dependent kinase are involved in anoikis induced by anicequol or 25-hydroxycholesterol in DLD-1 colon cancer cells. |
2013 |
Biochem. Biophys. Res. Commun. |
pmid:23266613
|
Tuong ZK et al. |
Disruption of Rorα1 and cholesterol 25-hydroxylase expression attenuates phagocytosis in male Rorαsg/sg mice. |
2013 |
Endocrinology |
pmid:23239817
|
Rodriguez-Lafrasse C et al. |
Abnormal cholesterol metabolism in imipramine-treated fibroblast cultures. Similarities with Niemann-Pick type C disease. |
1990 |
Biochim. Biophys. Acta |
pmid:2317521
|
Appelqvist H et al. |
Sensitivity to lysosome-dependent cell death is directly regulated by lysosomal cholesterol content. |
2012 |
PLoS ONE |
pmid:23166840
|
Ludes B et al. |
Increased immunogenicity of human renal carcinoma cells following treatment with cholesterol derivatives. |
1990 |
Eur. Urol. |
pmid:2311641
|
Kivelä AM et al. |
Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A. |
2012 |
Atherosclerosis |
pmid:23102786
|
Rosca AM et al. |
Cardiomyocyte apoptosis in ischaemia-reperfusion due to the exogenous oxidants at the time of reperfusion. |
2012 |
Cell Biol. Int. |
pmid:22994946
|
Baker ME et al. |
3D models of human ERα and ERβ complexed with 5-androsten-3β,17β-diol. |
2012 |
Steroids |
pmid:22921477
|
Goto A et al. |
Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis. |
2012 |
Mol. Biol. Cell |
pmid:22875984
|
Koarai A et al. |
25-Hydroxycholesterol enhances cytokine release and Toll-like receptor 3 response in airway epithelial cells. |
2012 |
Respir. Res. |
pmid:22849850
|
Zhu L and Bakovic M |
Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2. |
2008 |
Res Lett Biochem |
pmid:22820672
|
Parisio G et al. |
Flip-flop of steroids in phospholipid bilayers: effects of the chemical structure on transbilayer diffusion. |
2012 |
J. Am. Chem. Soc. |
pmid:22738146
|
Diczfalusy U |
On the formation and possible biological role of 25-hydroxycholesterol. |
2013 |
Biochimie |
pmid:22732193
|
Bai Q et al. |
VEGF is involved in the increase of dermal microvascular permeability induced by tryptase. |
2012 |
ISRN Dermatol |
pmid:22666607
|
Kostopoulou F et al. |
Central role of SREBP-2 in the pathogenesis of osteoarthritis. |
2012 |
PLoS ONE |
pmid:22662110
|
Nishigori M et al. |
Highly potent binding and inverse agonist activity of bisphenol A derivatives for retinoid-related orphan nuclear receptor RORγ. |
2012 |
Toxicol. Lett. |
pmid:22659100
|
Zhang J et al. |
Effect of triptolide on progesterone production from cultured rat granulosa cells. |
2012 |
Arzneimittelforschung |
pmid:22592319
|
Gold ES et al. |
ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation. |
2012 |
J. Exp. Med. |
pmid:22473958
|
Roberg-Larsen H et al. |
High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry. |
2012 |
J Chromatogr A |
pmid:22410154
|
Yu PL et al. |
Antisteroidogenic effects of hydrogen peroxide on rat granulosa cells. |
2012 |
Free Radic. Res. |
pmid:22397630
|
Battista PJ et al. |
Differential control of placental lactogen release and progesterone production by ovine placental tissue in vitro. |
1990 Jul-Aug |
Placenta |
pmid:2235915
|
Schumacher M et al. |
Progesterone synthesis in the nervous system: implications for myelination and myelin repair. |
2012 |
Front Neurosci |
pmid:22347156
|
Catarino S et al. |
Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells. |
2012 |
Acta Ophthalmol |
pmid:22313893
|
Sugiura H et al. |
Increased 25-hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease. |
2012 |
Respirology |
pmid:22295989
|
Patel NT and Thompson EB |
Human oxysterol-binding protein. I. Identification and characterization in liver. |
1990 |
J. Clin. Endocrinol. Metab. |
pmid:2229319
|
RodrÃguez-Carpena JG et al. |
Inhibition of cholesterol oxidation products (COPs) formation in emulsified porcine patties by phenolic-rich avocado (Persea americana Mill.) extracts. |
2012 |
J. Agric. Food Chem. |
pmid:22292505
|
Koo MS et al. |
Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages. |
2012 |
Cell Commun. Signal |
pmid:22280836
|
Lange Y et al. |
Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells. |
2012 |
PLoS ONE |
pmid:22276143
|
Xu L et al. |
25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages. |
2012 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:22275753
|
Guo J et al. |
HCV NS5A and NS5B enhance expression of human ceramide glucosyltransferase gene. |
2012 |
Virol Sin |
pmid:22270805
|
van Deursen D et al. |
Activation of hepatic lipase expression by oleic acid: possible involvement of USF1. |
2009 |
Nutrients |
pmid:22253973
|
Pardali E and Ten Dijke P |
TGFβ signaling and cardiovascular diseases. |
2012 |
Int. J. Biol. Sci. |
pmid:22253564
|
Lai YL et al. |
Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases. |
2012 |
J Clin Biochem Nutr |
pmid:22247606
|
Keller M et al. |
Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury. |
2011 |
PLoS ONE |
pmid:22242129
|
Aye IL et al. |
Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB. |
2012 |
Mol. Hum. Reprod. |
pmid:22238372
|
Bai Q et al. |
Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease. |
2012 |
Metab. Clin. Exp. |
pmid:22225954
|
Girard E et al. |
The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages. |
2011 |
PLoS ONE |
pmid:22205993
|
Wang Y et al. |
Nifedipine protects INS-1 β-cell from high glucose-induced ER stress and apoptosis. |
2011 |
Int J Mol Sci |
pmid:22174617
|
Bhushan S et al. |
Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege. |
2011 |
PLoS ONE |
pmid:22164293
|
Yashiro T et al. |
Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins. |
2012 |
Atherosclerosis |
pmid:22153697
|
Vallianou I et al. |
Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. |
2011 |
PLoS ONE |
pmid:22073134
|
Catalgol B and Kartal Ozer N |
Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis. |
2010 |
Curr Cardiol Rev |
pmid:22043207
|
Latif R et al. |
Steroidogenesis in amlodipine treated purified Leydig cells. |
2012 |
Toxicol. Appl. Pharmacol. |
pmid:22032983
|
Mouzat K et al. |
A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia. |
2011 |
BMC Med. Genet. |
pmid:22029530
|
Guyton JR et al. |
Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region. |
1990 |
Am. J. Pathol. |
pmid:2201200
|
Subathra M et al. |
Sphingomyelin synthases regulate protein trafficking and secretion. |
2011 |
PLoS ONE |
pmid:21980337
|
Wang F et al. |
Interferon regulator factor 1/retinoic inducible gene I (IRF1/RIG-I) axis mediates 25-hydroxycholesterol-induced interleukin-8 production in atherosclerosis. |
2012 |
Cardiovasc. Res. |
pmid:21979142
|
Iborra RT et al. |
Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. |
2011 |
Lipids Health Dis |
pmid:21957962
|
Cho SY et al. |
Linalool reduces the expression of 3-hydroxy-3-methylglutaryl CoA reductase via sterol regulatory element binding protein-2- and ubiquitin-dependent mechanisms. |
2011 |
FEBS Lett. |
pmid:21944868
|
Pachikian BD et al. |
Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets. |
2011 |
PLoS ONE |
pmid:21853118
|
Dasari B et al. |
Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. |
2011 |
BMC Ophthalmol |
pmid:21851605
|
Ebrahimi KB and Handa JT |
Lipids, lipoproteins, and age-related macular degeneration. |
2011 |
J Lipids |
pmid:21822496
|
Burgett AW et al. |
Natural products reveal cancer cell dependence on oxysterol-binding proteins. |
2011 |
Nat. Chem. Biol. |
pmid:21822274
|
Davis W |
The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells. |
2011 |
Biochim. Biophys. Acta |
pmid:21810484
|
Leonard S et al. |
Inhibition of isoprenoid biosynthesis and the post-translational modification of pro-p21. |
1990 |
J. Biol. Chem. |
pmid:2180959
|
Mazzone T et al. |
Relation of growth- and sterol-related regulatory pathways for low density lipoprotein receptor gene expression. |
1990 |
J. Biol. Chem. |
pmid:2180958
|
Liu C et al. |
Oxysterols direct B-cell migration through EBI2. |
2011 |
Nature |
pmid:21796211
|
Weber H et al. |
Dietary protein restriction stress and adrenocortical function: evidence for transient and long-term induction of enhanced cellular function. |
1990 |
Endocrinology |
pmid:2174347
|
Thorsell AG et al. |
Comparative structural analysis of lipid binding START domains. |
2011 |
PLoS ONE |
pmid:21738568
|
Rehman S et al. |
Antiviral drugs against hepatitis C virus. |
2011 |
Genet Vaccines Ther |
pmid:21699699
|
Zhou T et al. |
OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62. |
2011 |
PLoS ONE |
pmid:21698267
|
Zhong W et al. |
OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability. |
2011 |
Exp. Cell Res. |
pmid:21669198
|
Diczfalusy U and Björkhem I |
Still another activity by the highly promiscuous enzyme CYP3A4: 25-hydroxylation of cholesterol. |
2011 |
J. Lipid Res. |
pmid:21652732
|
Gu Y et al. |
Inhibitory effect of gossypol on steroidogenic pathways in cultured bovine luteal cells. |
1990 |
Biochem. Biophys. Res. Commun. |
pmid:2162666
|
Vejux A et al. |
Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments. |
2011 |
J Ophthalmol |
pmid:21577274
|
Honda A et al. |
Cholesterol 25-hydroxylation activity of CYP3A. |
2011 |
J. Lipid Res. |
pmid:21576599
|
Kamisuki S et al. |
Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. |
2011 |
J. Med. Chem. |
pmid:21561152
|
Medina MW et al. |
Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake. |
2011 |
PLoS ONE |
pmid:21559365
|
Siam A et al. |
Comparative modeling of 25-hydroxycholesterol-7α-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations. |
2012 |
J Mol Model |
pmid:21541746
|
Bielska AA et al. |
Synthesis of the enantiomer of the oxysterol-antagonist LY295427. |
2011 Sep-Oct |
Steroids |
pmid:21470559
|
Shan PF et al. |
Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells. |
2011 |
PLoS ONE |
pmid:21437254
|
Clariana M and GarcÃa-Regueiro JA |
Effect of high pressure processing on cholesterol oxidation products in vacuum packaged sliced dry-cured ham. |
2011 |
Food Chem. Toxicol. |
pmid:21426921
|
Jusakul A et al. |
Mechanisms of oxysterol-induced carcinogenesis. |
2011 |
Lipids Health Dis |
pmid:21388551
|
Jo Y et al. |
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. |
2011 |
J. Biol. Chem. |
pmid:21343306
|
Nantia EA et al. |
Effects of the methanol extract of Basella alba L (Basellaceae) on steroid production in Leydig cells. |
2011 |
Int J Mol Sci |
pmid:21339992
|
Olsen BN et al. |
25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes. |
2011 |
Biophys. J. |
pmid:21320439
|
Sonawane PJ et al. |
Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension. |
2011 |
PLoS ONE |
pmid:21304971
|
Lappano R et al. |
The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes. |
2011 |
PLoS ONE |
pmid:21304949
|
Plasen D et al. |
Initial response of endothelial cells to acute stimulation with a lipid component: increase cyclooxygenase activity by induction of COX-2 through activation of tyrosine kinase. |
2010 |
J Med Assoc Thai |
pmid:21299081
|
Boyce S et al. |
Reconstructed skin from cultured human keratinocytes and fibroblasts on a collagen-glycosaminoglycan biopolymer substrate. |
1990 |
Skin Pharmacol. |
pmid:2127678
|
den Uyl D et al. |
(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis. |
2011 |
Arthritis Res. Ther. |
pmid:21241491
|
Aye IL et al. |
Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors. |
2011 |
Placenta |
pmid:21208656
|
Panini SR et al. |
Defective elongation of fatty acids in a recessive 25-hydroxycholesterol-resistant mutant cell line. |
1990 |
J. Biol. Chem. |
pmid:2117604
|
Matsui M et al. |
Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter. |
2010 |
Chem. Biol. |
pmid:21168770
|
Bai Q et al. |
Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells. |
2011 |
Atherosclerosis |
pmid:21146170
|
McDonald JG and Russell DW |
Editorial: 25-Hydroxycholesterol: a new life in immunology. |
2010 |
J. Leukoc. Biol. |
pmid:21123296
|
Seillan C |
Oxysterol mediated changes in fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells. |
1990 |
Lipids |
pmid:2110280
|
Roby KF and Terranova PF |
Effects of tumor necrosis factor-alpha in vitro on steroidogenesis of healthy and atretic follicles of the rat: theca as a target. |
1990 |
Endocrinology |
pmid:2109690
|
Nguyen VP et al. |
25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner. |
2010 |
J Angiogenes Res |
pmid:21070649
|