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J Neural Transm |
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2002 Jan-Feb |
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Mol. Psychiatry |
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2002 |
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2003 Jan-Feb |
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Pharmacopsychiatry |
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2003 |
Biochemistry |
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2004 |
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2004 |
Steroids |
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J Neural Transm |
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Effect of raloxifene and hormone therapy on serum markers of brain and whole-body cholesterol metabolism in postmenopausal women. |
2005 |
Maturitas |
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2005 |
Neuroreport |
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2006 |
J Neural Transm |
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The effects of gender and CYP46 and apo E polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients treated with statins. |
2004 |
Curr Alzheimer Res |
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A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease. |
2005 |
J Clin Psychiatry |
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Clin. Chim. Acta |
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2006 |
Clin Neurol Neurosurg |
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2006 |
Eur. J. Clin. Pharmacol. |
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2006 Apr 10-17 |
Neurosci. Lett. |
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24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. |
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2006 |
Expert Rev Neurother |
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High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels. |
2006 |
J Clin Pharmacol |
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J. Neuropathol. Exp. Neurol. |
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2006 |
Acta Neurol. Scand., Suppl.c |
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Oxysterols and Alzheimer's disease. |
2006 |
Acta Neurol. Scand., Suppl.c |
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24S-hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical- and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression. |
2007 |
J. Neurochem. |
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Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. |
2007 |
Atherosclerosis |
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2006 |
J. Intern. Med. |
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Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. |
2007 |
Cell Metab. |
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2007 |
J. Lipid Res. |
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2007 |
Lipids |
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24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis. |
2007 |
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Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. |
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2007 |
Curr. Eye Res. |
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[A new synthesis of cerebrosterol and its 24-epimer from lithocholic acid]. |
2007 Mar-Apr |
Bioorg. Khim. |
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2007 |
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Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation. |
2007 |
Hum. Mol. Genet. |
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2008 |
Neurochem. Res. |
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Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders. |
2007 |
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Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier. |
2007 |
J. Neurochem. |
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27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. |
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Nat. Med. |
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Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals. |
2009 |
Neurobiol. Aging |
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The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome. |
2008 |
J. Proteome Res. |
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Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol. |
2008 |
Anal. Biochem. |
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Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury. |
2008 |
Brain Inj |
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Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease. |
2008 |
Brain |
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Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. |
2009 |
J. Lipid Res. |
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Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. |
2008 |
J. Neurochem. |
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A comparison of the potential unfavorable effects of oxycholesterol and oxyphytosterol in mice: different effects, on cerebral 24S-hydroxychoelsterol and serum triacylglycerols levels. |
2008 |
Biosci. Biotechnol. Biochem. |
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Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. |
2009 |
Mol Neurodegener |
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2009 |
Scand. J. Clin. Lab. Invest. |
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CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism. |
2009 |
Eur. Psychiatry |
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Steroid and protein ligand binding to cytochrome P450 46A1 as assessed by hydrogen-deuterium exchange and mass spectrometry. |
2009 |
Biochemistry |
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2009 |
Free Radic. Biol. Med. |
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The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo. |
2010 |
J. Lipid Res. |
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Primary open-angle glaucoma: association with cholesterol 24S-hydroxylase (CYP46A1) gene polymorphism and plasma 24-hydroxycholesterol levels. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
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Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. |
2009 |
Neurosci. Lett. |
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24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor activation. |
2009 |
Drug Metab. Dispos. |
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Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. |
2010 |
Mol. Ther. |
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Polar metabolite of cholesterol induces rat cognitive dysfunctions. |
2009 |
Neuroscience |
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24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury. |
2010 |
Brain Res. |
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A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol). |
2010 |
Biochim. Biophys. Acta |
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