Sugimoto H et al. |
Method development for the determination of 24S-hydroxycholesterol in human plasma without derivatization by high-performance liquid chromatography with tandem mass spectrometry in atmospheric pressure chemical ionization mode. |
2015 |
J Sep Sci |
pmid:26249017
|
Hughes TM et al. |
Brain cholesterol metabolism, oxysterols, and dementia. |
2013 |
J. Alzheimers Dis. |
pmid:23076077
|
Wang HL et al. |
Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-Analysis. |
2016 |
J. Alzheimers Dis. |
pmid:26836015
|
Hughes TM et al. |
Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease. |
2012 |
J. Alzheimers Dis. |
pmid:22377780
|
Pinçon A et al. |
Increased susceptibility of dyslipidemic LSR+/- mice to amyloid stress is associated with changes in cortical cholesterol levels. |
2015 |
J. Alzheimers Dis. |
pmid:25690661
|
Leoni V et al. |
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: candidate marker of brain health. |
2013 |
J. Alzheimers Dis. |
pmid:23666171
|
Saint-Pol J et al. |
Brain pericytes ABCA1 expression mediates cholesterol efflux but not cellular amyloid-β peptide accumulation. |
2012 |
J. Alzheimers Dis. |
pmid:22433669
|
Bodin K et al. |
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4. |
2001 |
J. Biol. Chem. |
pmid:11514559
|
Bjorkhem I et al. |
From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans. |
2001 |
J. Biol. Chem. |
pmid:11463788
|
Meir K et al. |
Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis. |
2002 |
J. Biol. Chem. |
pmid:12119285
|
Abildayeva K et al. |
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. |
2006 |
J. Biol. Chem. |
pmid:16524875
|
Li-Hawkins J et al. |
Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. |
2000 |
J. Biol. Chem. |
pmid:10748047
|
Lehmann JM et al. |
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. |
1997 |
J. Biol. Chem. |
pmid:9013544
|
Breuer O and Björkhem I |
Use of an 18O2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24-hydroxy-, and 25-hydroxycholesterol. |
1995 |
J. Biol. Chem. |
pmid:7657597
|
Björkhem I et al. |
Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro. |
1997 |
J. Biol. Chem. |
pmid:9374499
|
Mateos L et al. |
Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism. |
2011 |
J. Biol. Chem. |
pmid:21628469
|
Brown J et al. |
Differential expression of cholesterol hydroxylases in Alzheimer's disease. |
2004 |
J. Biol. Chem. |
pmid:15148325
|
Yamanaka K et al. |
24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis. |
2011 |
J. Biol. Chem. |
pmid:21613228
|
Björkhem I |
Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. |
2006 |
J. Intern. Med. |
pmid:17116000
|
Hansson M et al. |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. |
2007 |
J. Intern. Med. |
pmid:17444890
|