|
|
|
|
pmid:
|
Ziedén B et al. |
Increased plasma 7 beta-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease. |
1999 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10195924
|
Lizard G et al. |
Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall. |
1999 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10323769
|
Zarev S et al. |
Major differences in oxysterol formation in human low density lipoproteins (LDLs) oxidized by *OH/O2*- free radicals or by copper. |
1999 |
FEBS Lett. |
pmid:10371147
|
Kuroki S et al. |
Effects of cholestyramine on hepatic cholesterol 7alpha-hydroxylase and serum 7alpha-hydroxycholesterol in the hamster. |
1999 |
Lipids |
pmid:10529092
|
O'Callaghan YC et al. |
Oxysterol-induced cell death in U937 and HepG2 cells at reduced and normal serum concentrations. |
1999 |
Eur J Nutr |
pmid:10784381
|
O'Brien NM et al. |
Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: modulatory effects of phytochemicals. |
2000 |
Biochem. Soc. Trans. |
pmid:10816093
|
Li D and Spencer TA |
Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. |
2000 |
Steroids |
pmid:10978732
|
Bochelen D et al. |
7beta-hydroxysterol is cytotoxic to neonatal rat astrocytes in primary culture when cAMP levels are increased. |
2000 |
J. Neurosci. Res. |
pmid:11002292
|
Ares MP et al. |
7beta-hydroxycholesterol induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. |
2000 |
Atherosclerosis |
pmid:11058697
|
Meaney S et al. |
Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study. |
2001 |
J. Lipid Res. |
pmid:11160367
|
Lee T and Chau L |
Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells. |
2001 |
Am. J. Physiol., Cell Physiol. |
pmid:11171590
|
Lee JI et al. |
Formation of cholesterol oxides in irradiated raw and cooked chicken meat during storage. |
2001 |
Poult. Sci. |
pmid:11214329
|
Del Puppo M et al. |
Cholesterol metabolism in primary biliary cirrhosis during simvastatin and UDCA administration. |
2001 |
J. Lipid Res. |
pmid:11254756
|
Yasunobu Y et al. |
Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols. |
2001 |
Atherosclerosis |
pmid:11254916
|
Yang SC and Chen KH |
The oxidation of cholesterol in the yolk of selective traditional Chinese egg products. |
2001 |
Poult. Sci. |
pmid:11261569
|
Miguet C et al. |
Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. |
2001 |
Cell Death Differ. |
pmid:11313706
|
O'Callaghan YC et al. |
Limitations of the single-cell gel electrophoresis assay to monitor apoptosis in U937 and HepG2 cells exposed to 7beta-hydroxycholesterol. |
2001 |
Biochem. Pharmacol. |
pmid:11322925
|
Li W et al. |
Apoptotic death of inflammatory cells in human atheroma. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11451740
|
Bertolotti M et al. |
Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans. |
2001 |
Hepatology |
pmid:11481606
|
O'Callaghan YC et al. |
Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols. |
2001 |
Cell Biol. Toxicol. |
pmid:11499696
|
Iuliano L et al. |
Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11597949
|
Beaudeux JL et al. |
Comparison of the effects of O2*-/HO* free radical- and copper ions-oxidized LDL or lipoprotein(a) on the endothelial cell releases of tissue plasminogen activator and plasminogen activator inhibitor-1. |
2001 |
Life Sci. |
pmid:11681624
|
Bansal G et al. |
Effect of 7beta-hydroxycholesterol on cellular redox status and heat shock protein 70 expression in macrophages. |
2001 |
Cell. Physiol. Biochem. |
pmid:11684812
|
Rosenblat M and Aviram M |
Oxysterol-induced activation of macrophage NADPH-oxidase enhances cell-mediated oxidation of LDL in the atherosclerotic apolipoprotein E deficient mouse: inhibitory role for vitamin E. |
2002 |
Atherosclerosis |
pmid:11755924
|
Hayden JM et al. |
Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol. |
2002 |
J. Lipid Res. |
pmid:11792719
|
Duane WC and Javitt NB |
Conversion of 7 alpha-hydroxycholesterol to bile acid in human subjects: is there an alternate pathway favoring cholic acid synthesis? |
2002 |
J. Lab. Clin. Med. |
pmid:11919549
|
Meynier A et al. |
Effects of dietary oxysterols on coronary arteries in hyperlipidaemic hamsters. |
2002 |
Br. J. Nutr. |
pmid:12010578
|
O'Callaghan YC et al. |
Characteristics of 7 beta-hydroxycholesterol-induced cell death in a human monocytic blood cell line, U937, and a human hepatoma cell line, HepG2. |
2002 |
Toxicol In Vitro |
pmid:12020597
|
Tomoyori H et al. |
Lymphatic transport of dietary cholesterol oxidation products, cholesterol and triacylglycerols in rats. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12036056
|
Maeda Y et al. |
A comparative study of the conversion of 7-hydroxycholesterol in rabbit, guinea pig, rat, hamster, and chicken. |
2002 |
Steroids |
pmid:12117617
|
Gregorio-King CC et al. |
Effect of oxysterols on hematopoietic progenitor cells. |
2002 |
Exp. Hematol. |
pmid:12135663
|
Miguet-Alfonsi C et al. |
Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals. |
2002 |
Biochem. Pharmacol. |
pmid:12147305
|
Ando M et al. |
Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis. |
2002 |
Br. J. Nutr. |
pmid:12323083
|
Baggio SR et al. |
Cholesterol oxides, cholesterol, total lipid, and fatty acid composition in turkey meat. |
2002 |
J. Agric. Food Chem. |
pmid:12358469
|
Csallany AS et al. |
Protection of superoxide-induced cholesterol oxidation by antioxidants in protic conditions. |
2002 |
Int J Food Sci Nutr |
pmid:12396465
|
Uemura M et al. |
Alpha-tocopherol prevents apoptosis of vascular endothelial cells via a mechanism exceeding that of mere antioxidation. |
2002 |
Eur. J. Pharmacol. |
pmid:12450566
|
Ringseis R and Eder K |
Insufficient dietary vitamin e increases the concentration of 7beta-hydroxycholesterol in tissues of rats fed salmon oil. |
2002 |
J. Nutr. |
pmid:12468614
|
Linseisen J et al. |
Plasma 7beta-hydroxycholesterol as a possible predictor of lung cancer risk. |
2002 |
Cancer Epidemiol. Biomarkers Prev. |
pmid:12496054
|
Lim HK et al. |
Oxysterols induce apoptosis and accumulation of cell cycle at G(2)/M phase in the human monocytic THP-1 cell line. |
2003 |
Life Sci. |
pmid:12527036
|
Iuliano L et al. |
Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status. |
2003 |
Anal. Biochem. |
pmid:12531208
|
Chang MY et al. |
Lysophosphatidylcholine regulates synthesis of biglycan and the proteoglycan form of macrophage colony stimulating factor. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12663372
|
Monier S et al. |
Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12670484
|
O'Sullivan AJ et al. |
Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol. |
2003 May-Jun |
J Appl Toxicol |
pmid:12794941
|
Adachi J et al. |
Consecutive administration of paraquat to rats induces enhanced cholesterol peroxidation and lung injury. |
2003 |
Arch. Toxicol. |
pmid:12799775
|
Martin S et al. |
Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis. |
2003 |
Br. J. Pharmacol. |
pmid:12871827
|
Adachi J et al. |
7-hydroperoxycholesterol and oxysterols as indices of oxidative stress: chronic ethanol feeding and rat skeletal muscle. |
2003 |
Leg Med (Tokyo) |
pmid:12935564
|
Flader D et al. |
Effects of megadoses of dietary vitamin E on the antioxidant status of rats fed lard or salmon oil. |
2003 |
Int J Vitam Nutr Res |
pmid:12951900
|
Petrón MJ et al. |
Identification and quantification of cholesterol and cholesterol oxidation products in different types of Iberian hams. |
2003 |
J. Agric. Food Chem. |
pmid:12952434
|
Meaney S et al. |
On the origin of the cholestenoic acids in human circulation. |
2003 |
Steroids |
pmid:12957664
|
Maguire L et al. |
Comparison of the cytotoxic effects of beta-sitosterol oxides and a cholesterol oxide, 7beta-hydroxycholesterol, in cultured mammalian cells. |
2003 |
Br. J. Nutr. |
pmid:13129445
|
Behr P et al. |
Effect of dibutyryl cyclic AMP and isoproterenol on 7 beta-hydroxycholesterol cytotoxicity and esterification in spontaneous transformed cell lines derived from astrocyte primary cultures. |
1992 |
FEBS Lett. |
pmid:1330703
|
Kupferberg A et al. |
Separation and purification of dolichol and dolichyl phosphate by anion-exchange paper chromatography: application to cultured cells. |
1992 |
Anal. Biochem. |
pmid:1443591
|
Kishinaka M et al. |
Metabolism of intravenously administered 7 alpha-hydroxycholesterol-3 beta-stearate in the hamster. |
1992 |
Biochim. Biophys. Acta |
pmid:1450217
|
Tuomainen TP et al. |
Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man. |
2003 |
Free Radic. Biol. Med. |
pmid:14556856
|
Micheletta F et al. |
Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:14592846
|
Ciuffreda P et al. |
Synthesis of deuterated isotopomers of 7alpha- and (25R,S)-26-hydroxycholesterol, internal standards for in vivo determination of the two biosynthetic pathways of bile acids. |
2003 |
Steroids |
pmid:14625005
|
Bochelen D et al. |
7 beta-hydroxycholesterol and 7 beta-hydroxycholesteryl-3-esters reduce the extent of reactive gliosis caused by an electrolytic lesion in rat brain. |
1992 |
Neuroscience |
pmid:1488125
|
Schweizer RA et al. |
Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme. |
2004 |
J. Biol. Chem. |
pmid:14973125
|
Biasi F et al. |
Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: implications for proatherogenic gene modulation. |
2004 |
FASEB J. |
pmid:14977888
|
Ryan L et al. |
Generation of an oxidative stress precedes caspase activation during 7beta-hydroxycholesterol-induced apoptosis in U937 cells. |
2004 |
J. Biochem. Mol. Toxicol. |
pmid:14994280
|
Hult M et al. |
Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism. |
2004 |
Cell. Mol. Life Sci. |
pmid:15095019
|
Kontush A et al. |
Vitamin E is not deficient in human atherosclerotic plaques. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15237091
|
Shiotsuki H et al. |
Purification and characterization of 7beta-hydroxysteroid dehydrogenase from rabbit liver microsomes. |
2004 |
J. Steroid Biochem. Mol. Biol. |
pmid:15276626
|
Rodriguez IR et al. |
Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol. |
2004 |
Invest. Ophthalmol. Vis. Sci. |
pmid:15277510
|
Ringseis R and Eder K |
Effects of dietary fat and oxidized cholesterol on gene expression in rat liver as assessed by cDNA expression array analysis. |
2005 |
Eur J Nutr |
pmid:15309417
|
Sato H et al. |
Oxysterol regulation of estrogen receptor alpha-mediated gene expression in a transcriptional activation assay system using HeLa cells. |
2004 |
Biosci. Biotechnol. Biochem. |
pmid:15322366
|
Roussi S et al. |
Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells. |
2005 |
Cell Death Differ. |
pmid:15550935
|
Nelson TJ and Alkon DL |
Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. |
2005 |
J. Biol. Chem. |
pmid:15591071
|
Li W et al. |
Enhanced expression of natural resistance-associated macrophage protein 1 in atherosclerotic lesions may be associated with oxidized lipid-induced apoptosis. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659799
|
Li W and Yuan XM |
Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659826
|
Ryan L et al. |
Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2004 |
Cell Biol. Toxicol. |
pmid:15685934
|
Mast N et al. |
Cholesterol binding to cytochrome P450 7A1, a key enzyme in bile acid biosynthesis. |
2005 |
Biochemistry |
pmid:15736936
|
Del Puppo M et al. |
A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis. |
2005 |
Clin. Chim. Acta |
pmid:15820474
|
Raith K et al. |
A new LC/APCI-MS method for the determination of cholesterol oxidation products in food. |
2005 |
J Chromatogr A |
pmid:15844526
|
Boaz M et al. |
Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort. |
2005 |
Nephron Clin Pract |
pmid:15849477
|
O'sullivan AJ et al. |
Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells. |
2005 May-Jun |
Int. J. Toxicol. |
pmid:16040570
|
Kang KA et al. |
Cytotoxic effect of 7beta-hydroxycholesterol on human NCI-H460 lung cancer cells. |
2005 |
Biol. Pharm. Bull. |
pmid:16079477
|
Napolitano M and Bravo E |
Lipid metabolism and TNF-alpha secretion in response to dietary sterols in human monocyte derived macrophages. |
2005 |
Eur. J. Clin. Invest. |
pmid:16101668
|
Brunel JM et al. |
Synthesis and antifungal activity of oxygenated cholesterol derivatives. |
2005 |
Steroids |
pmid:16139854
|
Li W et al. |
Foam cell death induced by 7beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma. |
2005 |
Free Radic. Biol. Med. |
pmid:16140207
|
Lemaire-Ewing S et al. |
Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols. |
2005 |
Cell Biol. Toxicol. |
pmid:16142584
|
Ryan L et al. |
The role of the mitochondria in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2005 |
Br. J. Nutr. |
pmid:16197575
|
Guéguen Y et al. |
Short-term hepatic effects of depleted uranium on xenobiotic and bile acid metabolizing cytochrome P450 enzymes in the rat. |
2006 |
Arch. Toxicol. |
pmid:16231126
|
Nelson TJ and Alkon DL |
Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration. |
2005 |
Biochem. Soc. Trans. |
pmid:16246039
|
Corradini SG et al. |
High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation. |
2005 |
Liver Transpl. |
pmid:16258953
|
Prunet C et al. |
Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study. |
2005 |
J. Biochem. Mol. Toxicol. |
pmid:16292754
|
Adachi J et al. |
Skeletal muscle and liver oxysterols during fasting and alcohol exposure. |
2006 |
Metab. Clin. Exp. |
pmid:16324930
|
Ruiz E et al. |
Kaempferol inhibits apoptosis in vascular smooth muscle induced by a component of oxidized LDL. |
2006 |
Eur. J. Pharmacol. |
pmid:16325801
|
Prunet C et al. |
High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy. |
2006 |
Pathol. Biol. |
pmid:16376175
|
Yao Y et al. |
7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats. |
2006 |
Neuroscience |
pmid:16442740
|
Maeda Y et al. |
Species differences among various rodents in the conversion of 7alpha-hydroxycholesterol in liver microsomes. |
2006 |
Steroids |
pmid:16455124
|
Ryan L et al. |
Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis. |
2006 Jan-Feb |
Int. J. Toxicol. |
pmid:16510355
|
Chen ZH et al. |
Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. |
2006 |
J. Biol. Chem. |
pmid:16565077
|
Adachi J et al. |
Enhanced lipid peroxidation in tourniquet-release mice. |
2006 |
Clin. Chim. Acta |
pmid:16624265
|
Ferderbar S et al. |
Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. |
2007 |
Diabetes Metab. Res. Rev. |
pmid:16634125
|
Ruiz E et al. |
Human vascular smooth muscle cells from diabetic patients are resistant to induced apoptosis due to high Bcl-2 expression. |
2006 |
Diabetes |
pmid:16644678
|
Lee HW et al. |
Formation of cholesterol oxidation products in marinated foods during heating. |
2006 |
J. Agric. Food Chem. |
pmid:16787042
|
Rakotoarivelo C et al. |
7beta-hydroxycholesterol blocked at C-3-OH inhibits growth of rat glioblastoma in vivo: comparison between 7beta-hydroxycholesteryl-3beta (ester)-oleate and 7beta-hydroxycholesteryl-3-beta-O (ether)-oleyl. |
2006 May-Jun |
Anticancer Res. |
pmid:16827144
|
Larsson DA et al. |
Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects. |
2006 |
Free Radic. Biol. Med. |
pmid:16934673
|