Cho HR et al. |
7-Oxygenated cholesterol molecules differentially affect the expression of zonula occludens-1 in vascular smooth muscle cells and monocyte/macrophage cells. |
2018 |
Biochem. Biophys. Res. Commun. |
pmid:29428726
|
Cho HR et al. |
7α-Hydroxycholesterol induces monocyte/macrophage cell expression of interleukin-8 via C5a receptor. |
2017 |
PLoS ONE |
pmid:28323848
|
Deiana M et al. |
Derangement of intestinal epithelial cell monolayer by dietary cholesterol oxidation products. |
2017 |
Free Radic. Biol. Med. |
pmid:29102636
|
Stellaard F et al. |
The value of surrogate markers to monitor cholesterol absorption, synthesis and bioconversion to bile acids under lipid lowering therapies. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:27060336
|
Park SH et al. |
α-Asarone blocks 7β-hydroxycholesterol-exposed macrophage injury through blocking elF2α phosphorylation and prompting beclin-1-dependent autophagy. |
2017 |
Oncotarget |
pmid:28088783
|
Keune WJ et al. |
Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. |
2016 |
Nat Commun |
pmid:27075612
|
Musman J et al. |
Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice. |
2016 |
Free Radic. Biol. Med. |
pmid:27989751
|
Park SH et al. |
Dietary compound α-asarone alleviates ER stress-mediated apoptosis in 7β-hydroxycholesterol-challenged macrophages. |
2016 |
Mol Nutr Food Res |
pmid:26893256
|
Pataj Z et al. |
Quantification of oxysterols in human plasma and red blood cells by liquid chromatography high-resolution tandem mass spectrometry. |
2016 |
J Chromatogr A |
pmid:26607314
|
Son HH et al. |
Hair sterol signatures coupled to multivariate data analysis reveal an increased 7β-hydroxycholesterol production in cognitive impairment. |
2016 |
J. Steroid Biochem. Mol. Biol. |
pmid:26385606
|
Rasmiena AA et al. |
High density lipoprotein efficiently accepts surface but not internal oxidised lipids from oxidised low density lipoprotein. |
2016 |
Biochim. Biophys. Acta |
pmid:26569052
|
Frank DJ et al. |
Cytochrome P450 125A4, the Third Cholesterol C-26 Hydroxylase from Mycobacterium smegmatis. |
2015 |
Biochemistry |
pmid:26522442
|
Nury T et al. |
Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3). |
2015 |
Steroids |
pmid:25683890
|
Wang Y et al. |
Determination of neuroprotective oxysterols in Calculus bovis, human gallstones, and traditional Chinese medicine preparations by liquid chromatography with mass spectrometry. |
2015 |
J Sep Sci |
pmid:25545614
|
Kim SM et al. |
7α-Hydroxycholesterol induces inflammation by enhancing production of chemokine (C-C motif) ligand 2. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26474699
|
Weingärtner O et al. |
Vascular effects of oxysterols and oxyphytosterols in apoEÂ -/- mice. |
2015 |
Atherosclerosis |
pmid:25765595
|
Kim SM et al. |
27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes. |
2014 |
Toxicol. Appl. Pharmacol. |
pmid:24370436
|
Helmschrodt C et al. |
Preanalytical standardization for reactive oxygen species derived oxysterol analysis in human plasma by liquid chromatography-tandem mass spectrometry. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24370823
|
Testa G et al. |
Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols. |
2014 |
PLoS ONE |
pmid:24802026
|
Khatib S and Vaya J |
Oxysterols and symptomatic versus asymptomatic human atherosclerotic plaque. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24393847
|
Ikegami T et al. |
Increased serum oxysterol concentrations in patients with chronic hepatitis C virus infection. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24525121
|
Saito Y and Noguchi N |
7-Hydroxycholestrol as a possible biomarker of cellular lipid peroxidation: difference between cellular and plasma lipid peroxidation. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24380859
|
Hammoud Y et al. |
Oxysterols modulate calcium signalling in the A7r5 aortic smooth muscle cell-line. |
2013 |
Biochimie |
pmid:22960205
|
Hirayama S et al. |
Ezetimibe decreases serum oxidized cholesterol without impairing bile acid synthesis in Japanese hypercholesterolemic patients. |
2013 |
Atherosclerosis |
pmid:23958251
|
Wang SF et al. |
7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells. |
2013 |
Biochem. Pharmacol. |
pmid:23792120
|
Chung ML et al. |
Profiling of oxidized lipid products of marine fish under acute oxidative stress. |
2013 |
Food Chem. Toxicol. |
pmid:23220612
|
Mitić T et al. |
11β-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7β-hydroxycholesterol. |
2013 |
Biochimie |
pmid:22940536
|
Miah S et al. |
Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53. |
2013 |
Exp. Toxicol. Pathol. |
pmid:22999639
|
Mitić T et al. |
11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo. |
2013 |
Biochem. Pharmacol. |
pmid:23415904
|
Ragot K et al. |
Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes. |
2013 |
Biochem. Pharmacol. |
pmid:23473804
|
Son Y et al. |
Oxysterols induce transition of monocytic cells to phenotypically mature dendritic cell-like cells. |
2013 |
Biochem. Biophys. Res. Commun. |
pmid:23876312
|
Loke SY et al. |
Comprehensive gene expression analyses of the rat prefrontal cortex after oxysterol treatment. |
2013 |
J. Neurochem. |
pmid:23294445
|
Seet RC et al. |
Biomarkers of oxidative damage are elevated among individuals with high cardiovascular risk: refining subject selection strategies for antioxidant trials. |
2013 |
Free Radic. Res. |
pmid:23343456
|
de Weille J et al. |
Similar pyruvate kinase modifications in glioblastoma cells by 7β-hydroxycholesterol and glutamine withdrawal. |
2013 |
Biochem. Pharmacol. |
pmid:23537700
|
Laskar A et al. |
Fodipir and its dephosphorylated derivative dipyridoxyl ethyldiamine are involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. |
2013 |
Pharmacology |
pmid:24080534
|
Helmschrodt C et al. |
Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque. |
2013 |
Clin. Chim. Acta |
pmid:23827692
|
Clarion L et al. |
7β-Hydroxycholesterol-induced energy stress leads to sequential opposing signaling responses and to death of C6 glioblastoma cells. |
2012 |
Biochem. Pharmacol. |
pmid:21983033
|
Catarino S et al. |
Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells. |
2012 |
Acta Ophthalmol |
pmid:22313893
|
Li W et al. |
Cell death induced by 7-oxysterols via lysosomal and mitochondrial pathways is p53-dependent. |
2012 |
Free Radic. Biol. Med. |
pmid:22985798
|
Arciello M et al. |
Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients. |
2012 |
Dig Liver Dis |
pmid:22154950
|
Gamba P et al. |
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime. |
2011 |
Aging Cell |
pmid:21272192
|
Iborra RT et al. |
Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. |
2011 |
Lipids Health Dis |
pmid:21957962
|
Li W et al. |
Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21621514
|
Seet RC et al. |
Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress? |
2011 |
Free Radic. Biol. Med. |
pmid:21420490
|
Goldman A et al. |
The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cells. |
2011 |
PLoS ONE |
pmid:21887327
|
Jusakul A et al. |
Mechanisms of oxysterol-induced carcinogenesis. |
2011 |
Lipids Health Dis |
pmid:21388551
|
Liu C et al. |
Oxysterols direct B-cell migration through EBI2. |
2011 |
Nature |
pmid:21796211
|
Vestergaard MC et al. |
The effect of oxycholesterols on thermo-induced membrane dynamics. |
2011 |
Biochim. Biophys. Acta |
pmid:21600872
|
Wong WT et al. |
Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta. |
2011 |
Nutr Metab Cardiovasc Dis |
pmid:20005687
|
Jenner AM et al. |
The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice. |
2010 |
Neuroscience |
pmid:20416362
|
Mascia C et al. |
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate. |
2010 |
Free Radic. Biol. Med. |
pmid:20923702
|
Tang Z and Guengerich FP |
Dansylation of unactivated alcohols for improved mass spectral sensitivity and application to analysis of cytochrome P450 oxidation products in tissue extracts. |
2010 |
Anal. Chem. |
pmid:20795636
|
Wang Y et al. |
Isolation and identification of two steroid compounds from Oviductus Ranae. |
2010 |
Nat. Prod. Res. |
pmid:20835952
|
Trevisi L et al. |
Antiapoptotic and proliferative effects of low concentrations of 7β-hydroxycholesterol in human endothelial cells via ERK activation. |
2010 |
J. Vasc. Res. |
pmid:19893321
|
Laskar A et al. |
Prevention of 7β-hydroxycholesterol-induced cell death by mangafodipir is mediated through lysosomal and mitochondrial pathways. |
2010 |
Eur. J. Pharmacol. |
pmid:20452343
|
Laskar A et al. |
Dimethyl sulfoxide prevents 7β-hydroxycholesterol-induced apoptosis by preserving lysosomes and mitochondria. |
2010 |
J. Cardiovasc. Pharmacol. |
pmid:20571430
|
Kahn E et al. |
Iron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells. |
2010 |
Int J Nanomedicine |
pmid:20463934
|
Lordan S et al. |
The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2009 Sep-Oct |
J. Biochem. Mol. Toxicol. |
pmid:19827036
|
Mazalli MR and Bragagnolo N |
Increase of cholesterol oxidation and decrease of PUFA as a result of thermal processing and storage in eggs enriched with n-3 fatty acids. |
2009 |
J. Agric. Food Chem. |
pmid:19438228
|
Heiduschka G et al. |
7beta-hydroxycholesterol induces apoptosis and regulates cyclooxygenase 2 in head and neck squamous cell carcinoma. |
2009 |
Arch. Otolaryngol. Head Neck Surg. |
pmid:19289704
|
Tang Z et al. |
Elucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approaches. |
2009 |
Anal. Chem. |
pmid:19301915
|
Li W et al. |
7beta-hydroxycholesterol induces natural killer cell death via oxidative lysosomal destabilization. |
2009 |
Free Radic. Res. |
pmid:19707922
|
Mitomo H et al. |
Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease? |
2009 |
J. Am. Chem. Soc. |
pmid:19658396
|
Lemaire-Ewing S et al. |
7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent. |
2009 |
Cell Biol. Toxicol. |
pmid:18317936
|
Iuliano L et al. |
Association of cholesterol oxidation and abnormalities in fatty acid metabolism in cystic fibrosis. |
2009 |
Am. J. Clin. Nutr. |
pmid:19587087
|
Li W et al. |
Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis. |
2009 |
Atherosclerosis |
pmid:18495127
|
Honda A et al. |
Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. |
2009 |
J. Lipid Res. |
pmid:18815436
|
Seet RC et al. |
Oxidative damage in dengue fever. |
2009 |
Free Radic. Biol. Med. |
pmid:19427377
|
Xu G et al. |
Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants. |
2009 |
J. Agric. Food Chem. |
pmid:19754120
|
Rosa A et al. |
Protective effect of the oligomeric acylphloroglucinols from Myrtus communis on cholesterol and human low density lipoprotein oxidation. |
2008 |
Chem. Phys. Lipids |
pmid:18498764
|
Lordan S et al. |
Effects of apigenin, lycopene and astaxanthin on 7 beta-hydroxycholesterol-induced apoptosis and Akt phosphorylation in U937 cells. |
2008 |
Br. J. Nutr. |
pmid:18186953
|
Li W et al. |
NK cell apoptosis in coronary artery disease: relation to oxidative stress. |
2008 |
Atherosclerosis |
pmid:18068708
|
Crosignani A et al. |
Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis. |
2008 |
Clin. Chim. Acta |
pmid:18538136
|
Lee CY et al. |
Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample. |
2008 |
Free Radic. Biol. Med. |
pmid:18226605
|
Vejux A et al. |
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis. |
2008 |
Braz. J. Med. Biol. Res. |
pmid:18719735
|
Kim DH and Frangos JA |
Effects of amyloid beta-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols. |
2008 |
Biophys. J. |
pmid:18390616
|
Malvitte L et al. |
Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol. |
2008 |
Curr. Eye Res. |
pmid:18798080
|
Zapolska-Downar D et al. |
Anthocyanin-rich Aronox extract from Aronia melanocarpa E protects against 7beta-hydroxycholesterol-induced apoptosis of endothelial cells. |
2008 |
Ann. Nutr. Metab. |
pmid:19142035
|
Fuhrman B et al. |
Ox-LDL induces monocyte-to-macrophage differentiation in vivo: Possible role for the macrophage colony stimulating factor receptor (M-CSF-R). |
2008 |
Atherosclerosis |
pmid:17675037
|
Lordan S et al. |
Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis. |
2008 |
Int. J. Toxicol. |
pmid:18569169
|
Menéndez-Carreño M et al. |
Inhibition of serum cholesterol oxidation by dietary vitamin C and selenium intake in high fat fed rats. |
2008 |
Lipids |
pmid:18335267
|
Alkazemi D et al. |
Oxysterol as a marker of atherogenic dyslipidemia in adolescence. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18713821
|
Wamil M et al. |
7-oxysterols modulate glucocorticoid activity in adipocytes through competition for 11beta-hydroxysteroid dehydrogenase type. |
2008 |
Endocrinology |
pmid:18755798
|
Lordan S et al. |
Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2007 |
J. Biochem. Mol. Toxicol. |
pmid:17994574
|
Mazalli MR and Bragagnolo N |
Effect of storage on cholesterol oxide formation and fatty acid alterations in egg powder. |
2007 |
J. Agric. Food Chem. |
pmid:17348676
|
Yoshida Y et al. |
Levels of lipid peroxidation in human plasma and erythrocytes: comparison between fatty acids and cholesterol. |
2007 |
Lipids |
pmid:17476548
|
Ferderbar S et al. |
Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. |
2007 |
Diabetes Metab. Res. Rev. |
pmid:16634125
|
Kitano S et al. |
Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). |
2007 |
Anal. Chim. Acta |
pmid:17386651
|
Nashev LG et al. |
Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. |
2007 |
PLoS ONE |
pmid:17593962
|
Vejux A et al. |
Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation. |
2007 |
Histochem. Cell Biol. |
pmid:17226048
|
Arca M et al. |
Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy. |
2007 |
Free Radic. Biol. Med. |
pmid:17291993
|
Erridge C et al. |
25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages. |
2007 |
Free Radic. Res. |
pmid:17364953
|
Hansson M et al. |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. |
2007 |
J. Intern. Med. |
pmid:17444890
|
Engel T et al. |
Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol. |
2007 |
FEBS Lett. |
pmid:17408620
|
Larsson H et al. |
In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress. |
2007 |
Free Radic. Biol. Med. |
pmid:17664133
|
Roussi S et al. |
Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells. |
2007 |
Apoptosis |
pmid:17136497
|
Crosignani A et al. |
Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease. |
2007 |
Clin. Chim. Acta |
pmid:17482152
|
Bravo E and Napolitano M |
Mechanisms involved in chylomicron remnant lipid uptake by macrophages. |
2007 |
Biochem. Soc. Trans. |
pmid:17511627
|
Rakotoarivelo C et al. |
7beta-hydroxycholesterol blocked at C-3-OH inhibits growth of rat glioblastoma in vivo: comparison between 7beta-hydroxycholesteryl-3beta (ester)-oleate and 7beta-hydroxycholesteryl-3-beta-O (ether)-oleyl. |
2006 May-Jun |
Anticancer Res. |
pmid:16827144
|
Ryan L et al. |
Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis. |
2006 Jan-Feb |
Int. J. Toxicol. |
pmid:16510355
|