Arciello M et al. |
Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients. |
2012 |
Dig Liver Dis |
pmid:22154950
|
Clarion L et al. |
7β-Hydroxycholesterol-induced energy stress leads to sequential opposing signaling responses and to death of C6 glioblastoma cells. |
2012 |
Biochem. Pharmacol. |
pmid:21983033
|
Iborra RT et al. |
Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. |
2011 |
Lipids Health Dis |
pmid:21957962
|
Goldman A et al. |
The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cells. |
2011 |
PLoS ONE |
pmid:21887327
|
Liu C et al. |
Oxysterols direct B-cell migration through EBI2. |
2011 |
Nature |
pmid:21796211
|
Li W et al. |
Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21621514
|
Vestergaard MC et al. |
The effect of oxycholesterols on thermo-induced membrane dynamics. |
2011 |
Biochim. Biophys. Acta |
pmid:21600872
|
Seet RC et al. |
Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress? |
2011 |
Free Radic. Biol. Med. |
pmid:21420490
|
Jusakul A et al. |
Mechanisms of oxysterol-induced carcinogenesis. |
2011 |
Lipids Health Dis |
pmid:21388551
|
Gamba P et al. |
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime. |
2011 |
Aging Cell |
pmid:21272192
|
Carpenter KL et al. |
Oxidation of cholesteryl linoleate by human monocyte-macrophages in vitro. |
1990 |
Atherosclerosis |
pmid:2122906
|
Mascia C et al. |
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate. |
2010 |
Free Radic. Biol. Med. |
pmid:20923702
|
Wang Y et al. |
Isolation and identification of two steroid compounds from Oviductus Ranae. |
2010 |
Nat. Prod. Res. |
pmid:20835952
|
Tang Z and Guengerich FP |
Dansylation of unactivated alcohols for improved mass spectral sensitivity and application to analysis of cytochrome P450 oxidation products in tissue extracts. |
2010 |
Anal. Chem. |
pmid:20795636
|
Laskar A et al. |
Dimethyl sulfoxide prevents 7β-hydroxycholesterol-induced apoptosis by preserving lysosomes and mitochondria. |
2010 |
J. Cardiovasc. Pharmacol. |
pmid:20571430
|
Kahn E et al. |
Iron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells. |
2010 |
Int J Nanomedicine |
pmid:20463934
|
Laskar A et al. |
Prevention of 7β-hydroxycholesterol-induced cell death by mangafodipir is mediated through lysosomal and mitochondrial pathways. |
2010 |
Eur. J. Pharmacol. |
pmid:20452343
|
Jenner AM et al. |
The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice. |
2010 |
Neuroscience |
pmid:20416362
|
Axelson M et al. |
Ethanol has an acute effect on bile acid biosynthesis in man. |
1991 |
FEBS Lett. |
pmid:2015886
|
Behr P et al. |
Effect of 7 beta-hydroxycholesterol on astrocyte primary cultures and derived spontaneously transformed cell lines. Cytotoxicity and cholesterogenesis. |
1991 |
FEBS Lett. |
pmid:2013313
|
Wong WT et al. |
Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta. |
2011 |
Nutr Metab Cardiovasc Dis |
pmid:20005687
|
Trevisi L et al. |
Antiapoptotic and proliferative effects of low concentrations of 7β-hydroxycholesterol in human endothelial cells via ERK activation. |
2010 |
J. Vasc. Res. |
pmid:19893321
|
Lordan S et al. |
The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2009 Sep-Oct |
J. Biochem. Mol. Toxicol. |
pmid:19827036
|
Xu G et al. |
Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants. |
2009 |
J. Agric. Food Chem. |
pmid:19754120
|
Li W et al. |
7beta-hydroxycholesterol induces natural killer cell death via oxidative lysosomal destabilization. |
2009 |
Free Radic. Res. |
pmid:19707922
|
Mitomo H et al. |
Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease? |
2009 |
J. Am. Chem. Soc. |
pmid:19658396
|
Iuliano L et al. |
Association of cholesterol oxidation and abnormalities in fatty acid metabolism in cystic fibrosis. |
2009 |
Am. J. Clin. Nutr. |
pmid:19587087
|
Mazalli MR and Bragagnolo N |
Increase of cholesterol oxidation and decrease of PUFA as a result of thermal processing and storage in eggs enriched with n-3 fatty acids. |
2009 |
J. Agric. Food Chem. |
pmid:19438228
|
Seet RC et al. |
Oxidative damage in dengue fever. |
2009 |
Free Radic. Biol. Med. |
pmid:19427377
|
Tang Z et al. |
Elucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approaches. |
2009 |
Anal. Chem. |
pmid:19301915
|
Heiduschka G et al. |
7beta-hydroxycholesterol induces apoptosis and regulates cyclooxygenase 2 in head and neck squamous cell carcinoma. |
2009 |
Arch. Otolaryngol. Head Neck Surg. |
pmid:19289704
|
Zapolska-Downar D et al. |
Anthocyanin-rich Aronox extract from Aronia melanocarpa E protects against 7beta-hydroxycholesterol-induced apoptosis of endothelial cells. |
2008 |
Ann. Nutr. Metab. |
pmid:19142035
|
Pettersen KS et al. |
Toxicity of oxygenated cholesterol derivatives toward cultured human umbilical vein endothelial cells. |
1991 Mar-Apr |
Arterioscler. Thromb. |
pmid:1900193
|
Honda A et al. |
Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. |
2009 |
J. Lipid Res. |
pmid:18815436
|
Malvitte L et al. |
Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol. |
2008 |
Curr. Eye Res. |
pmid:18798080
|
Wamil M et al. |
7-oxysterols modulate glucocorticoid activity in adipocytes through competition for 11beta-hydroxysteroid dehydrogenase type. |
2008 |
Endocrinology |
pmid:18755798
|
Vejux A et al. |
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis. |
2008 |
Braz. J. Med. Biol. Res. |
pmid:18719735
|
Alkazemi D et al. |
Oxysterol as a marker of atherogenic dyslipidemia in adolescence. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18713821
|
Lordan S et al. |
Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis. |
2008 |
Int. J. Toxicol. |
pmid:18569169
|
Crosignani A et al. |
Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis. |
2008 |
Clin. Chim. Acta |
pmid:18538136
|
Rosa A et al. |
Protective effect of the oligomeric acylphloroglucinols from Myrtus communis on cholesterol and human low density lipoprotein oxidation. |
2008 |
Chem. Phys. Lipids |
pmid:18498764
|
Li W et al. |
Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis. |
2009 |
Atherosclerosis |
pmid:18495127
|
Kim DH and Frangos JA |
Effects of amyloid beta-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols. |
2008 |
Biophys. J. |
pmid:18390616
|
Menéndez-Carreño M et al. |
Inhibition of serum cholesterol oxidation by dietary vitamin C and selenium intake in high fat fed rats. |
2008 |
Lipids |
pmid:18335267
|
Lemaire-Ewing S et al. |
7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent. |
2009 |
Cell Biol. Toxicol. |
pmid:18317936
|
Lee CY et al. |
Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample. |
2008 |
Free Radic. Biol. Med. |
pmid:18226605
|
Lordan S et al. |
Effects of apigenin, lycopene and astaxanthin on 7 beta-hydroxycholesterol-induced apoptosis and Akt phosphorylation in U937 cells. |
2008 |
Br. J. Nutr. |
pmid:18186953
|
Li W et al. |
NK cell apoptosis in coronary artery disease: relation to oxidative stress. |
2008 |
Atherosclerosis |
pmid:18068708
|
Lordan S et al. |
Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2007 |
J. Biochem. Mol. Toxicol. |
pmid:17994574
|
Fuhrman B et al. |
Ox-LDL induces monocyte-to-macrophage differentiation in vivo: Possible role for the macrophage colony stimulating factor receptor (M-CSF-R). |
2008 |
Atherosclerosis |
pmid:17675037
|
Larsson H et al. |
In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress. |
2007 |
Free Radic. Biol. Med. |
pmid:17664133
|
Nashev LG et al. |
Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. |
2007 |
PLoS ONE |
pmid:17593962
|
Bravo E and Napolitano M |
Mechanisms involved in chylomicron remnant lipid uptake by macrophages. |
2007 |
Biochem. Soc. Trans. |
pmid:17511627
|
Crosignani A et al. |
Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease. |
2007 |
Clin. Chim. Acta |
pmid:17482152
|
Yoshida Y et al. |
Levels of lipid peroxidation in human plasma and erythrocytes: comparison between fatty acids and cholesterol. |
2007 |
Lipids |
pmid:17476548
|
Hansson M et al. |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. |
2007 |
J. Intern. Med. |
pmid:17444890
|
Engel T et al. |
Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol. |
2007 |
FEBS Lett. |
pmid:17408620
|
Kitano S et al. |
Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). |
2007 |
Anal. Chim. Acta |
pmid:17386651
|
Erridge C et al. |
25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages. |
2007 |
Free Radic. Res. |
pmid:17364953
|
Mazalli MR and Bragagnolo N |
Effect of storage on cholesterol oxide formation and fatty acid alterations in egg powder. |
2007 |
J. Agric. Food Chem. |
pmid:17348676
|
Arca M et al. |
Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy. |
2007 |
Free Radic. Biol. Med. |
pmid:17291993
|
Vejux A et al. |
Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation. |
2007 |
Histochem. Cell Biol. |
pmid:17226048
|
Roussi S et al. |
Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells. |
2007 |
Apoptosis |
pmid:17136497
|
Roussi S et al. |
Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. |
2006 |
Int. J. Oncol. |
pmid:17088995
|
Bai B et al. |
Combined effect of 25-hydroxycholesterol and IL-1beta on IL-8 production in human colon carcinoma cell line (Caco-2). |
2005 |
Inflammation |
pmid:17086498
|
Nakagawa K et al. |
Protective effect of daidzein against acute ethanol-induced lipid peroxidation in rat jejunum. |
2006 |
Kobe J Med Sci |
pmid:17006054
|
Hall MC |
The effect of oxysterols, individually and as a representative mixture from food, on in vitro cultured bovine ovarian granulosa cells. |
2006 |
Mol. Cell. Biochem. |
pmid:16983501
|
Steffen Y et al. |
Cytotoxicity of myeloperoxidase/nitrite-oxidized low-density lipoprotein toward endothelial cells is due to a high 7beta-hydroxycholesterol to 7-ketocholesterol ratio. |
2006 |
Free Radic. Biol. Med. |
pmid:16962939
|
Massey JB and Pownall HJ |
Structures of biologically active oxysterols determine their differential effects on phospholipid membranes. |
2006 |
Biochemistry |
pmid:16939227
|
Larsson DA et al. |
Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects. |
2006 |
Free Radic. Biol. Med. |
pmid:16934673
|
Rakotoarivelo C et al. |
7beta-hydroxycholesterol blocked at C-3-OH inhibits growth of rat glioblastoma in vivo: comparison between 7beta-hydroxycholesteryl-3beta (ester)-oleate and 7beta-hydroxycholesteryl-3-beta-O (ether)-oleyl. |
2006 May-Jun |
Anticancer Res. |
pmid:16827144
|
Lee HW et al. |
Formation of cholesterol oxidation products in marinated foods during heating. |
2006 |
J. Agric. Food Chem. |
pmid:16787042
|
Ruiz E et al. |
Human vascular smooth muscle cells from diabetic patients are resistant to induced apoptosis due to high Bcl-2 expression. |
2006 |
Diabetes |
pmid:16644678
|
Ferderbar S et al. |
Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. |
2007 |
Diabetes Metab. Res. Rev. |
pmid:16634125
|
Adachi J et al. |
Enhanced lipid peroxidation in tourniquet-release mice. |
2006 |
Clin. Chim. Acta |
pmid:16624265
|
Chen ZH et al. |
Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. |
2006 |
J. Biol. Chem. |
pmid:16565077
|
Ryan L et al. |
Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis. |
2006 Jan-Feb |
Int. J. Toxicol. |
pmid:16510355
|
Maeda Y et al. |
Species differences among various rodents in the conversion of 7alpha-hydroxycholesterol in liver microsomes. |
2006 |
Steroids |
pmid:16455124
|
Yao Y et al. |
7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats. |
2006 |
Neuroscience |
pmid:16442740
|
Prunet C et al. |
High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy. |
2006 |
Pathol. Biol. |
pmid:16376175
|
Ruiz E et al. |
Kaempferol inhibits apoptosis in vascular smooth muscle induced by a component of oxidized LDL. |
2006 |
Eur. J. Pharmacol. |
pmid:16325801
|
Adachi J et al. |
Skeletal muscle and liver oxysterols during fasting and alcohol exposure. |
2006 |
Metab. Clin. Exp. |
pmid:16324930
|
Prunet C et al. |
Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study. |
2005 |
J. Biochem. Mol. Toxicol. |
pmid:16292754
|
Corradini SG et al. |
High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation. |
2005 |
Liver Transpl. |
pmid:16258953
|
Nelson TJ and Alkon DL |
Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration. |
2005 |
Biochem. Soc. Trans. |
pmid:16246039
|
Guéguen Y et al. |
Short-term hepatic effects of depleted uranium on xenobiotic and bile acid metabolizing cytochrome P450 enzymes in the rat. |
2006 |
Arch. Toxicol. |
pmid:16231126
|
Ryan L et al. |
The role of the mitochondria in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2005 |
Br. J. Nutr. |
pmid:16197575
|
Lemaire-Ewing S et al. |
Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols. |
2005 |
Cell Biol. Toxicol. |
pmid:16142584
|
Li W et al. |
Foam cell death induced by 7beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma. |
2005 |
Free Radic. Biol. Med. |
pmid:16140207
|
Brunel JM et al. |
Synthesis and antifungal activity of oxygenated cholesterol derivatives. |
2005 |
Steroids |
pmid:16139854
|
Napolitano M and Bravo E |
Lipid metabolism and TNF-alpha secretion in response to dietary sterols in human monocyte derived macrophages. |
2005 |
Eur. J. Clin. Invest. |
pmid:16101668
|
Kang KA et al. |
Cytotoxic effect of 7beta-hydroxycholesterol on human NCI-H460 lung cancer cells. |
2005 |
Biol. Pharm. Bull. |
pmid:16079477
|
O'sullivan AJ et al. |
Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells. |
2005 May-Jun |
Int. J. Toxicol. |
pmid:16040570
|
Boaz M et al. |
Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort. |
2005 |
Nephron Clin Pract |
pmid:15849477
|
Raith K et al. |
A new LC/APCI-MS method for the determination of cholesterol oxidation products in food. |
2005 |
J Chromatogr A |
pmid:15844526
|
Del Puppo M et al. |
A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis. |
2005 |
Clin. Chim. Acta |
pmid:15820474
|
Mast N et al. |
Cholesterol binding to cytochrome P450 7A1, a key enzyme in bile acid biosynthesis. |
2005 |
Biochemistry |
pmid:15736936
|
Ryan L et al. |
Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. |
2004 |
Cell Biol. Toxicol. |
pmid:15685934
|
Li W and Yuan XM |
Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659826
|
Li W et al. |
Enhanced expression of natural resistance-associated macrophage protein 1 in atherosclerotic lesions may be associated with oxidized lipid-induced apoptosis. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659799
|