Adiguzel Z et al. |
Evaluation of apoptotic molecular pathways for smooth muscle cells isolated from thoracic aortic aneurysms in response to oxidized sterols. |
2014 |
Mol. Biol. Rep. |
pmid:25266234
|
Son Y et al. |
7-Ketocholesterol induces the reduction of KCNMB1 in atherosclerotic blood vessels. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:25576871
|
Lee DH et al. |
Rotundarpene attenuates cholesterol oxidation product-induced apoptosis by suppressing the mitochondrial pathway and the caspase-8- and bid-dependent pathways. |
2015 |
Eur. J. Pharmacol. |
pmid:25592323
|
Lee JW et al. |
Extra-hepatic metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2α and SOAT1 followed by selective efflux to HDL. |
2015 |
Biochim. Biophys. Acta |
pmid:25617738
|
Rosales C et al. |
CD1d serves as a surface receptor for oxidized cholesterol induction of peroxisome proliferator-activated receptor-γ. |
2015 |
Atherosclerosis |
pmid:25618030
|
Shi G et al. |
Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow-Derived Cells Differ Markedly in Their Production of IL-1β and IL-18. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:25678688
|
Nury T et al. |
Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3). |
2015 |
Steroids |
pmid:25683890
|
Luchetti F et al. |
7-Ketocholesterol and 5,6-secosterol induce human endothelial cell dysfunction by differential mechanisms. |
2015 |
Steroids |
pmid:25697053
|
Guina T et al. |
The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics. |
2015 |
Food Funct |
pmid:25736858
|
Chen Y et al. |
THP1 macrophages oxidized cholesterol, generating 7-derivative oxysterols specifically released by HDL. |
2015 |
Steroids |
pmid:25742736
|
Karilainen T et al. |
Oxidation of cholesterol does not alter significantly its uptake into high-density lipoprotein particles. |
2015 |
J Phys Chem B |
pmid:25768721
|
Indaram M et al. |
7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration. |
2015 |
Sci Rep |
pmid:25775051
|
Klinke G et al. |
LC-MS/MS based assay and reference intervals in children and adolescents for oxysterols elevated in Niemann-Pick diseases. |
2015 |
Clin. Biochem. |
pmid:25819840
|
Lee DH et al. |
Quercetin-3-O-(2″-galloyl)-α-L-rhamnopyranoside attenuates cholesterol oxidation product-induced apoptosis by suppressing NF-κB-mediated cell death process in differentiated PC12 cells. |
2015 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:25845326
|
Moinard C et al. |
Citrulline Supplementation Induces Changes in Body Composition and Limits Age-Related Metabolic Changes in Healthy Male Rats. |
2015 |
J. Nutr. |
pmid:26019250
|
Davis S et al. |
α-Tocopherols modify the membrane dipole potential leading to modulation of ligand binding by P-glycoprotein. |
2015 |
J. Lipid Res. |
pmid:26026069
|
Laparra JM et al. |
7keto-stigmasterol and 7keto-cholesterol induce differential proteome changes to intestinal epitelial (Caco-2) cells. |
2015 |
Food Chem. Toxicol. |
pmid:26140950
|
Pajares S et al. |
Cholestane-3β,5α,6β-triol: high levels in Niemann-Pick type C, cerebrotendinous xanthomatosis, and lysosomal acid lipase deficiency. |
2015 |
J. Lipid Res. |
pmid:26239048
|
Xu M et al. |
Contribution of Nrf2 to Atherogenic Phenotype Switching of Coronary Arterial Smooth Muscle Cells Lacking CD38 Gene. |
2015 |
Cell. Physiol. Biochem. |
pmid:26315049
|
Telesford DM et al. |
Reduced Condensing and Ordering Effects by 7-Ketocholesterol and 5β,6β-Epoxycholesterol on DPPC Monolayers. |
2015 |
Langmuir |
pmid:26322794
|
Sudo R et al. |
7-Ketocholesterol-induced lysosomal dysfunction exacerbates vascular smooth muscle cell calcification via oxidative stress. |
2015 |
Genes Cells |
pmid:26419830
|
Rasmiena AA et al. |
High density lipoprotein efficiently accepts surface but not internal oxidised lipids from oxidised low density lipoprotein. |
2016 |
Biochim. Biophys. Acta |
pmid:26569052
|
Pataj Z et al. |
Quantification of oxysterols in human plasma and red blood cells by liquid chromatography high-resolution tandem mass spectrometry. |
2016 |
J Chromatogr A |
pmid:26607314
|
Gajewski A et al. |
Helicobacter pylori antigens, acetylsalicylic acid, LDL and 7-ketocholesterol - their potential role in destabilizing the gastric epithelial cell barrier. An in vitro model of Kato III cells. |
2016 |
Acta Biochim. Pol. |
pmid:26619253
|
Alba G et al. |
7-Keto-cholesterol and 25-hydroxy-1 cholesterol rapidly enhance ROS production in human neutrophils. |
2016 |
Eur J Nutr |
pmid:26715521
|
Boenzi S et al. |
Evaluation of plasma cholestane-3β,5α,6β-triol and 7-ketocholesterol in inherited disorders related to cholesterol metabolism. |
2016 |
J. Lipid Res. |
pmid:26733147
|
Romanello M et al. |
Comprehensive Evaluation of Plasma 7-Ketocholesterol and Cholestan-3β,5α,6β-Triol in an Italian Cohort of Patients Affected by Niemann-Pick Disease due to NPC1 and SMPD1 Mutations. |
2016 |
Clin. Chim. Acta |
pmid:26790753
|
Zarrouk A et al. |
Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158N murine oligodendrocytes. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:26921765
|
Tran J et al. |
Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells. |
2016 |
PLoS ONE |
pmid:26977592
|
Ghosh S and Khare SK |
Biodegradation of cytotoxic 7-Ketocholesterol by Pseudomonas aeruginosa PseA. |
2016 |
Bioresour. Technol. |
pmid:27020128
|
Leoni V et al. |
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:27020660
|
Nury T et al. |
7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:27041118
|
Silva SF et al. |
Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:27133385
|
Zhan X et al. |
[Blood 7-ketocholesterol level, clinical features and gene mutation analysis of 18 children with Niemann-Pick disease type C]. |
2016 |
Zhonghua Er Ke Za Zhi |
pmid:27256227
|
Sanda GM et al. |
Oxidized LDL-Exposed Human Macrophages Display Increased MMP-9 Expression and Secretion Mediated by Endoplasmic Reticulum Stress. |
2017 |
J. Cell. Biochem. |
pmid:27341688
|
Rosa Fernandes L et al. |
7-Ketocholesterol overcomes drug resistance in chronic myeloid leukemia cell lines beyond MDR1 mechanism. |
2017 |
J Proteomics |
pmid:27343758
|
Pang C et al. |
Biotransformation of cholesterol and 16,17-alpha epoxypregnenolone by novel Cladosporium sp. strain IS547. |
2017 |
J. Basic Microbiol. |
pmid:27690325
|
Chang MC et al. |
7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells. |
2016 |
Oncotarget |
pmid:27740938
|
Debbabi M et al. |
Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells. |
2016 |
Int J Mol Sci |
pmid:27897980
|
Musman J et al. |
Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice. |
2016 |
Free Radic. Biol. Med. |
pmid:27989751
|
Bezine M et al. |
Evidence of K homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes. |
2017 |
Chem. Phys. Lipids |
pmid:28322741
|
Cho HR et al. |
7α-Hydroxycholesterol induces monocyte/macrophage cell expression of interleukin-8 via C5a receptor. |
2017 |
PLoS ONE |
pmid:28323848
|
Ward LJ et al. |
Exposure to atheroma-relevant 7-oxysterols causes proteomic alterations in cell death, cellular longevity, and lipid metabolism in THP-1 macrophages. |
2017 |
PLoS ONE |
pmid:28350877
|
Song J et al. |
Association of Plasma 7-Ketocholesterol With Cardiovascular Outcomes and Total Mortality in Patients With Coronary Artery Disease. |
2017 |
Circ. Res. |
pmid:28381400
|
Debbabi M et al. |
Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells. |
2017 |
Chem. Phys. Lipids |
pmid:28408132
|
Wang M et al. |
Plasma 7-ketocholesterol levels and the risk of incident cardiovascular events. |
2017 |
Heart |
pmid:28490621
|
Ghosh S and Khare SK |
Biodegradation of 7-Ketocholesterol by Rhodococcus erythropolis MTCC 3951: Process optimization and enzymatic insights. |
2017 |
Chem. Phys. Lipids |
pmid:28571786
|
Wang Y et al. |
Mitochondrial Oxidative Stress Promotes Atherosclerosis and Neutrophil Extracellular Traps in Aged Mice. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28596373
|
Koka S et al. |
Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia. |
2017 |
Redox Biol |
pmid:28633109
|
Rosa-Fernandes L et al. |
Outside-in, inside-out: Proteomic analysis of endothelial stress mediated by 7-ketocholesterol. |
2017 |
Chem. Phys. Lipids |
pmid:28663071
|