Chien JT et al. |
Integral kinetic model for studying quercetin degradation and oxidation as affected by cholesterol during heating. |
2010 |
Int J Mol Sci |
pmid:21152275
|
Badreddine A et al. |
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N. |
2017 |
Int J Mol Sci |
pmid:29065513
|
Islam MO et al. |
Generation and characterization of a novel recombinant antibody against 15-ketocholestane isolated by phage-display. |
2012 |
Int J Mol Sci |
pmid:22606021
|
Kahn E et al. |
Iron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells. |
2010 |
Int J Nanomedicine |
pmid:20463934
|
Lyons MA and Brown AJ |
7-Ketocholesterol. |
1999 Mar-Apr |
Int. J. Biochem. Cell Biol. |
pmid:10224662
|
Kiss L et al. |
Effects of 7-ketocholesterol on the activity of endothelial poly(ADP-ribose) polymerase and on endothelium-dependent relaxant function. |
2006 |
Int. J. Mol. Med. |
pmid:17089016
|
Butterfield DA et al. |
Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. |
2012 |
Int. J. Neuropsychopharmacol. |
pmid:21767440
|
Luthra S et al. |
Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17122150
|
Rodriguez IR et al. |
Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol. |
2004 |
Invest. Ophthalmol. Vis. Sci. |
pmid:15277510
|
Wu M et al. |
Oxidative and endoplasmic reticulum stresses mediate apoptosis induced by modified LDL in human retinal Müller cells. |
2012 |
Invest. Ophthalmol. Vis. Sci. |
pmid:22678501
|
Moreira EF et al. |
7-Ketocholesterol is present in lipid deposits in the primate retina: potential implication in the induction of VEGF and CNV formation. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
pmid:18936140
|
Gramajo AL et al. |
Mitochondrial DNA damage induced by 7-ketocholesterol in human retinal pigment epithelial cells in vitro. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:19834037
|
Larrayoz IM et al. |
7-ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NFκB but independently of reactive oxygen species formation. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:20554621
|
Shi G et al. |
Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow-Derived Cells Differ Markedly in Their Production of IL-1β and IL-18. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:25678688
|
Neekhra A et al. |
Caspase-8, -12, and -3 activation by 7-ketocholesterol in retinal neurosensory cells. |
2007 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17325185
|
Zunin P et al. |
Sterol oxidation in meat- and fish-based homogenized baby foods containing vegetable oils. |
2006 Mar-Apr |
J AOAC Int |
pmid:16640291
|
Raith K et al. |
A new LC/APCI-MS method for the determination of cholesterol oxidation products in food. |
2005 |
J Chromatogr A |
pmid:15844526
|
Pataj Z et al. |
Quantification of oxysterols in human plasma and red blood cells by liquid chromatography high-resolution tandem mass spectrometry. |
2016 |
J Chromatogr A |
pmid:26607314
|
Shui G et al. |
Derivatization-independent cholesterol analysis in crude lipid extracts by liquid chromatography/mass spectrometry: applications to a rabbit model for atherosclerosis. |
2011 |
J Chromatogr A |
pmid:21621788
|
Lai YL et al. |
Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases. |
2012 |
J Clin Biochem Nutr |
pmid:22247606
|
Noguchi N |
Role of oxidative stress in adaptive responses in special reference to atherogenesis. |
2008 |
J Clin Biochem Nutr |
pmid:19015746
|
Katsuyama M et al. |
Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme. |
2012 |
J Clin Biochem Nutr |
pmid:22247596
|
Niki E |
Do free radicals play causal role in atherosclerosis? Low density lipoprotein oxidation and vitamin E revisited. |
2011 |
J Clin Biochem Nutr |
pmid:21297905
|
Pratt HP et al. |
Membrane sterols and the development of the preimplantation mouse embryo. |
1980 |
J Embryol Exp Morphol |
pmid:7031162
|
Ebrahimi KB and Handa JT |
Lipids, lipoproteins, and age-related macular degeneration. |
2011 |
J Lipids |
pmid:21822496
|
Cohen E et al. |
Increased Levels of Human Carotid Lesion Linoleic Acid Hydroperoxide in Symptomatic and Asymptomatic Patients Is Inversely Correlated with Serum HDL and Paraoxonase 1 Activity. |
2012 |
J Lipids |
pmid:22690338
|
Itabe H et al. |
The Dynamics of Oxidized LDL during Atherogenesis. |
2011 |
J Lipids |
pmid:21660303
|
Kim YJ et al. |
7-Ketocholesterol enhances 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells. |
2006 |
J Neural Transm |
pmid:16715209
|
Haider N et al. |
Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis. |
2009 Sep-Oct |
J Nucl Cardiol |
pmid:19662466
|
Vejux A et al. |
Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments. |
2011 |
J Ophthalmol |
pmid:21577274
|
Karilainen T et al. |
Oxidation of cholesterol does not alter significantly its uptake into high-density lipoprotein particles. |
2015 |
J Phys Chem B |
pmid:25768721
|
Rosa Fernandes L et al. |
7-Ketocholesterol overcomes drug resistance in chronic myeloid leukemia cell lines beyond MDR1 mechanism. |
2017 |
J Proteomics |
pmid:27343758
|
Mazalli MR and Bragagnolo N |
Increase of cholesterol oxidation and decrease of PUFA as a result of thermal processing and storage in eggs enriched with n-3 fatty acids. |
2009 |
J. Agric. Food Chem. |
pmid:19438228
|
Echarte M et al. |
Oxidation process affecting fatty acids and cholesterol in fried and roasted salmon. |
2001 |
J. Agric. Food Chem. |
pmid:11714374
|
Tian L et al. |
Red and white wines inhibit cholesterol oxidation induced by free radicals. |
2011 |
J. Agric. Food Chem. |
pmid:21563753
|
Lee HW et al. |
Formation of cholesterol oxidation products in marinated foods during heating. |
2006 |
J. Agric. Food Chem. |
pmid:16787042
|
Mazalli MR and Bragagnolo N |
Effect of storage on cholesterol oxide formation and fatty acid alterations in egg powder. |
2007 |
J. Agric. Food Chem. |
pmid:17348676
|
Bortolomeazzi R et al. |
Presence of phytosterol oxides in crude vegetable oils and their fate during refining. |
2003 |
J. Agric. Food Chem. |
pmid:12670187
|
Baggio SR et al. |
Cholesterol oxides, cholesterol, total lipid, and fatty acid composition in turkey meat. |
2002 |
J. Agric. Food Chem. |
pmid:12358469
|
Wong D and Wang M |
Inhibitory activities of some vitamins on the formation of cholesterol oxidation products in beef patties. |
2013 |
J. Agric. Food Chem. |
pmid:23937446
|
RodrÃguez-Carpena JG et al. |
Inhibition of cholesterol oxidation products (COPs) formation in emulsified porcine patties by phenolic-rich avocado (Persea americana Mill.) extracts. |
2012 |
J. Agric. Food Chem. |
pmid:22292505
|
Rosa A et al. |
Protective effect of vanilloids against tert-butyl hydroperoxide-induced oxidative stress in vero cells culture. |
2008 |
J. Agric. Food Chem. |
pmid:18439017
|
Suh MH et al. |
Antioxidative activity of microencapsulated gamma-oryzanol on high cholesterol-fed rats. |
2005 |
J. Agric. Food Chem. |
pmid:16332125
|
Petrón MJ et al. |
Identification and quantification of cholesterol and cholesterol oxidation products in different types of Iberian hams. |
2003 |
J. Agric. Food Chem. |
pmid:12952434
|
Xu G et al. |
Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants. |
2009 |
J. Agric. Food Chem. |
pmid:19754120
|
Miyashita Y et al. |
Apoptosis induced by 7-ketocholesterol is enhanced in smooth muscle cells derived from OLETF rats. |
2005 |
J. Atheroscler. Thromb. |
pmid:15942119
|
Ohtsuka M et al. |
Lipids deposited in human atheromatous lesions induce apoptosis of human vascular smooth muscle cells. |
2006 |
J. Atheroscler. Thromb. |
pmid:17146154
|
Saito E et al. |
7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells. |
2008 |
J. Atheroscler. Thromb. |
pmid:18603819
|
Oyama T et al. |
Effect of deposited lipids in atheromatous lesions on the migration of vascular smooth muscle cells. |
2002 |
J. Atheroscler. Thromb. |
pmid:12236314
|
Miyashita Y et al. |
Oxysterol-induced apoptosis of vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitor, pravastatin. |
2002 |
J. Atheroscler. Thromb. |
pmid:12238640
|
Hakamata H et al. |
Cytotoxic effect of oxidized low density lipoprotein on macrophages. |
1998 |
J. Atheroscler. Thromb. |
pmid:10855560
|
Hitsumoto T et al. |
Clinical significance of serum 7-ketocholesterol concentrations in the progression of coronary atherosclerosis. |
2009 |
J. Atheroscler. Thromb. |
pmid:19672027
|
Ozaki H et al. |
Enhancement of MMP-9 activity in THP-1 cells by 7-ketocholesterol and its suppression by the HMG-CoA reductase inhibitor fluvastatin. |
2005 |
J. Atheroscler. Thromb. |
pmid:16394614
|
Pang C et al. |
Biotransformation of cholesterol and 16,17-alpha epoxypregnenolone by novel Cladosporium sp. strain IS547. |
2017 |
J. Basic Microbiol. |
pmid:27690325
|
Prunet C et al. |
Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study. |
2005 |
J. Biochem. Mol. Toxicol. |
pmid:16292754
|
Kawai Y et al. |
Covalent binding of oxidized cholesteryl esters to protein: implications for oxidative modification of low density lipoprotein and atherosclerosis. |
2003 |
J. Biol. Chem. |
pmid:12663661
|
Gelissen IC et al. |
Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol. |
1996 |
J. Biol. Chem. |
pmid:8663356
|
Rusiñol AE et al. |
AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis. |
2004 |
J. Biol. Chem. |
pmid:14559920
|
Han J et al. |
Oxidized low density lipoprotein decreases macrophage expression of scavenger receptor B-I. |
2001 |
J. Biol. Chem. |
pmid:11278882
|
Sevanian A and McLeod LL |
Catalytic properties and inhibition of hepatic cholesterol-epoxide hydrolase. |
1986 |
J. Biol. Chem. |
pmid:3941086
|
Royer MC et al. |
7-ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death. |
2009 |
J. Biol. Chem. |
pmid:19351882
|
Savouret JF et al. |
7-ketocholesterol is an endogenous modulator for the arylhydrocarbon receptor. |
2001 |
J. Biol. Chem. |
pmid:11042205
|
Breuer O and Björkhem I |
Use of an 18O2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24-hydroxy-, and 25-hydroxycholesterol. |
1995 |
J. Biol. Chem. |
pmid:7657597
|
Brown AJ et al. |
Sterol 27-hydroxylase acts on 7-ketocholesterol in human atherosclerotic lesions and macrophages in culture. |
2000 |
J. Biol. Chem. |
pmid:10869358
|
Frick C et al. |
Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase. |
2004 |
J. Biol. Chem. |
pmid:15152005
|
Kimura T et al. |
Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11427538
|
Charvet C et al. |
Isolevuglandins and mitochondrial enzymes in the retina: mass spectrometry detection of post-translational modification of sterol-metabolizing CYP27A1. |
2011 |
J. Biol. Chem. |
pmid:21498512
|
Schweizer RA et al. |
Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme. |
2004 |
J. Biol. Chem. |
pmid:14973125
|
Moreira EF et al. |
Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina. |
2001 |
J. Biol. Chem. |
pmid:11278871
|
Zhang Y et al. |
Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1. |
2003 |
J. Biol. Chem. |
pmid:12533546
|
Shinkyo R et al. |
Conversion of 7-dehydrocholesterol to 7-ketocholesterol is catalyzed by human cytochrome P450 7A1 and occurs by direct oxidation without an epoxide intermediate. |
2011 |
J. Biol. Chem. |
pmid:21813643
|
Kritharides L et al. |
Hydroxypropyl-beta-cyclodextrin-mediated efflux of 7-ketocholesterol from macrophage foam cells. |
1996 |
J. Biol. Chem. |
pmid:8910326
|
Romeo GR and Kazlauskas A |
Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1. |
2008 |
J. Biol. Chem. |
pmid:18230613
|
Perales S et al. |
Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia. |
2009 |
J. Biomed. Biotechnol. |
pmid:19727411
|
Kim WK et al. |
Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells. |
2010 |
J. Bone Miner. Res. |
pmid:19839776
|
Son Y et al. |
Roles of 7-ketocholesterol on the homeostasis of intracellular cholesterol level. |
2012 |
J. Cardiovasc. Pharmacol. |
pmid:22622234
|
Sanda GM et al. |
Oxidized LDL-Exposed Human Macrophages Display Increased MMP-9 Expression and Secretion Mediated by Endoplasmic Reticulum Stress. |
2017 |
J. Cell. Biochem. |
pmid:27341688
|
Schrader C et al. |
Genistein as a potential inducer of the anti-atherogenic enzyme paraoxonase-1: studies in cultured hepatocytes in vitro and in rat liver in vivo. |
2012 |
J. Cell. Mol. Med. |
pmid:22304296
|
Ingueneau C et al. |
TRPC1 is regulated by caveolin-1 and is involved in oxidized LDL-induced apoptosis of vascular smooth muscle cells. |
2009 |
J. Cell. Mol. Med. |
pmid:20187291
|
Anticoli S et al. |
7-ketocholesterol and 5,6-secosterol modulate differently the stress-activated mitogen-activated protein kinases (MAPKs) in liver cells. |
2010 |
J. Cell. Physiol. |
pmid:19937729
|
Alkazemi D et al. |
Oxysterol as a marker of atherogenic dyslipidemia in adolescence. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18713821
|
Terasaka N et al. |
ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. |
2008 |
J. Clin. Invest. |
pmid:18924609
|
Diestel A et al. |
Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage. |
2003 |
J. Exp. Med. |
pmid:14657223
|
Mariutti LR et al. |
Lipid and cholesterol oxidation in chicken meat are inhibited by sage but not by garlic. |
2011 |
J. Food Sci. |
pmid:22417489
|
Gaspari AA and Rietschel RL |
Anti-inflammatory properties of an oxidized sterol. |
1985 |
J. Invest. Dermatol. |
pmid:3968446
|
Sankaranarayanan S et al. |
Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux. |
2009 |
J. Lipid Res. |
pmid:18827283
|
Vine DF et al. |
Dietary oxysterols are incorporated in plasma triglyceride-rich lipoproteins, increase their susceptibility to oxidation and increase aortic cholesterol concentration of rabbits. |
1998 |
J. Lipid Res. |
pmid:9788246
|
Hakamata H et al. |
Isolation of macrophage-like cell mutants resistant to the cytotoxic effect of oxidized low density lipoprotein. |
1998 |
J. Lipid Res. |
pmid:9548582
|
Gelissen IC et al. |
Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid. |
1999 |
J. Lipid Res. |
pmid:10484610
|
Brown AJ et al. |
Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells. Accumulation of oxidized esters in lysosomes. |
2000 |
J. Lipid Res. |
pmid:10681406
|
Hynynen R et al. |
OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids. |
2009 |
J. Lipid Res. |
pmid:19224871
|
Heo GY et al. |
Conversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells. |
2011 |
J. Lipid Res. |
pmid:21411718
|
Akiba S et al. |
Oxidized LDL activates phospholipase A2 to supply fatty acids required for cholesterol esterification. |
2003 |
J. Lipid Res. |
pmid:12777475
|
Boenzi S et al. |
Evaluation of plasma cholestane-3β,5α,6β-triol and 7-ketocholesterol in inherited disorders related to cholesterol metabolism. |
2016 |
J. Lipid Res. |
pmid:26733147
|
Pajares S et al. |
Cholestane-3β,5α,6β-triol: high levels in Niemann-Pick type C, cerebrotendinous xanthomatosis, and lysosomal acid lipase deficiency. |
2015 |
J. Lipid Res. |
pmid:26239048
|
Davis S et al. |
α-Tocopherols modify the membrane dipole potential leading to modulation of ligand binding by P-glycoprotein. |
2015 |
J. Lipid Res. |
pmid:26026069
|
Leoni V et al. |
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis. |
2005 |
J. Lipid Res. |
pmid:15576852
|
Kratzer A et al. |
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. |
2009 |
J. Lipid Res. |
pmid:18812595
|
McCourt MP et al. |
X-ray crystal structure of cytotoxic oxidized cholesterols: 7-ketocholesterol and 25-hydroxycholesterol. |
1997 |
J. Lipid Res. |
pmid:9186918
|
Lyons MA et al. |
Rapid hepatic metabolism of 7-ketocholesterol in vivo: implications for dietary oxysterols. |
1999 |
J. Lipid Res. |
pmid:10508204
|