MeSH term | MeSH ID | Detail |
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Hyperlipoproteinemias | D006951 | 15 associated lipids |
Cholestane-3beta,5alpha,6beta-triol is a lipid of Sterol Lipids (ST) class. Cholestane-3beta,5alpha,6beta-triol is associated with abnormalities such as Niemann-Pick Diseases, Hypercholesterolemia, Familial, Xanthomatosis, Cerebrotendinous, Neurodegenerative Disorders and Metabolic Diseases. The involved functions are known as Adjudication, Oxidation, Mutation, cholesterol transport and Process. Cholestane-3beta,5alpha,6beta-triol often locates in Lysosomal, Blood, Body tissue, peroxisome and Cytoplasmic Granules. The associated genes with Cholestane-3beta,5alpha,6beta-triol are CALCA gene, NPC2 gene, Alleles, SNW1 Gene and ADRBK1 gene. The related lipids are 7-ketocholesterol, Sterols and Cholestanes.
To understand associated biological information of Cholestane-3beta,5alpha,6beta-triol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cholestane-3beta,5alpha,6beta-triol is suspected in Hypercholesterolemia, Familial, Galactosemias, Liver diseases, Niemann-Pick Diseases, Xanthomatosis, Cerebrotendinous, Metabolic Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Cholestane-3beta,5alpha,6beta-triol
MeSH term | MeSH ID | Detail |
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Hyperlipoproteinemias | D006951 | 15 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Zhou Q et al. | The accentuating effect of low magnesium concentration on cholestane-3 beta, 5 alpha, 6 beta-triol-induced decrease of LDL uptake by cultured endothelial cells. | 1999 | Magnes Res | pmid:10423703 |
Yoshida T et al. | Cholestan-3beta,5alpha,6beta-triol, but not 7-ketocholesterol, suppresses taurocholate-induced mucin secretion by cultured dog gallbladder epithelial cells. | 2000 | FEBS Lett. | pmid:10922480 |
D'Armas HT et al. | Steroidal compounds from the Caribbean octocoral Eunicea laciniata. | 2000 | J. Nat. Prod. | pmid:11141111 |
Yoshida T et al. | Effects of bile salts on cholestan-3beta,5alpha,6beta-triol-induced apoptosis in dog gallbladder epithelial cells. | 2001 | Biochim. Biophys. Acta | pmid:11239822 |
Huang K et al. | Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats. | 2002 | Atherosclerosis | pmid:11947907 |
Zhou Q et al. | Effect of low magnesium concentration and cholestane-3beta, 5alpha, 6beta-triol on levels of LDL receptor in cultured fibroblasts. | 2002 | Magnes Res | pmid:12030421 |
Ren D et al. | Effects of salvianolic acids on endothelial cells against damage induced by cholestane-3beta-5alpha-6beta-triol. | 2003 | Chin. Med. J. | pmid:12875737 |
Ramasamy S et al. | Oxysterol-induced endothelial cell dysfunction in culture. | 1992 | J Am Coll Nutr | pmid:1333499 |
Dorset DL | Binary phase behavior of angiotoxic oxidized cholesterols with cholesterol. | 1992 | Biochim. Biophys. Acta | pmid:1511006 |