Cholesta-4,6-dien-3-one

Cholesta-4,6-dien-3-one is a lipid of Sterol Lipids (ST) class. Cholesta-4,6-dien-3-one is associated with abnormalities such as Paracoccidioidomycosis and Acquired partial lipodystrophy. The involved functions are known as Stereochemistry, Oxidation, Saturated, Drug Interactions and Synthesis. Cholesta-4,6-dien-3-one often locates in Tissue membrane, Cell membrane, lipid raft, Membrane and Head. The related lipids are Sterols, cholesterol analog, cholesta-5,7,9-trien-3 beta-ol, stearic acid and Sphingolipids.

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Introduction

To understand associated biological information of Cholesta-4,6-dien-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cholesta-4,6-dien-3-one?

Cholesta-4,6-dien-3-one is suspected in Paracoccidioidomycosis, Acquired partial lipodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Cholesta-4,6-dien-3-one

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cholesta-4,6-dien-3-one?

Related references are published most in these journals:

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What functions are associated with Cholesta-4,6-dien-3-one?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cholesta-4,6-dien-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Cholesta-4,6-dien-3-one?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Cholesta-4,6-dien-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Cholesta-4,6-dien-3-one

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Authors Title Published Journal PubMed Link
Scheidt HA et al. The potential of fluorescent and spin-labeled steroid analogs to mimic natural cholesterol. 2003 J. Biol. Chem. pmid:12947110
Liu R et al. Characterization of fluorescent sterol binding to purified human NPC1. 2009 J. Biol. Chem. pmid:19029290
Sklar LA et al. Induced circular dichroism of incorporated fluorescent cholesteryl esters and polar lipids as a probe of human serum low density lipoprotein structure and melting. 1981 J. Biol. Chem. pmid:7217083
Skrede S et al. Hepatic 7 alpha-dehydroxylation of bile acid intermediates, and its significance for the pathogenesis of cerebrotendinous xanthomatosis. 1988 J. Lipid Res. pmid:3367085
Parish EJ et al. New chemical syntheses of cholest-4,6-dien-3-one. 2002 Lipids pmid:12617475
Jusakul A et al. Liver fluke-induced hepatic oxysterols stimulate DNA damage and apoptosis in cultured human cholangiocytes. 2012 Mutat. Res. pmid:22044627
Hebting Y et al. Biomarker evidence for a major preservation pathway of sedimentary organic carbon. 2006 Science pmid:16690819
Kim E and Ma E Chemoselective reduction of 1,4,6-cholestatrien-3-one and 1,4,6-androstatriene-3,17-dione by various hydride reagents. 2007 Steroids pmid:17303200