Zymosterol

Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zymosterol?

Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zymosterol

MeSH term MeSH ID Detail
Limb Deformities, Congenital D017880 4 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zymosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zymosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Zymosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Zymosterol?

Related references are published most in these journals:

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What genes are associated with Zymosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zymosterol?

Knock-out

Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Zymosterol

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Authors Title Published Journal PubMed Link
Snitkin ES et al. Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions. 2008 Genome Biol. pmid:18808699
de Souza W and Rodrigues JC Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. 2009 Interdiscip Perspect Infect Dis pmid:19680554
Kawashima H et al. Differences in sterol composition of gonads of the lottiid limpets Nipponacmea concinna and Nipponacmea fuscoviridis from northeastern Japan. 2011 J Oleo Sci pmid:21937849
Nakanishi S et al. Preparation of 14C-labeled and unlabeled sterol intermediates from yeast using metabolic inhibitors. 1984 J. Biochem. pmid:6397465
Nishino T et al. Subcellular localization of the enzymes involved in the late stage of ergosterol biosynthesis in yeast. 1981 J. Biochem. pmid:7024258
Nes WD et al. Active site mapping and substrate channeling in the sterol methyltransferase pathway. 2002 J. Biol. Chem. pmid:12196515
Lange Y Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone. 1994 J. Biol. Chem. pmid:8106380
Baudry K et al. The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae. 2001 J. Biol. Chem. pmid:11279045
Swain E et al. Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiae. 2002 J. Biol. Chem. pmid:12006573
Lusa S et al. Differential mobilization of newly synthesized cholesterol and biosynthetic sterol precursors from cells. 2003 J. Biol. Chem. pmid:12657643